903 resultados para VESTIBULAR DYSFUNCTION
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The maintenance of a given body orientation is obtained by the complex relation between sensory information and muscle activity. Therefore, this study purpose was to review the role of visual, somatosensory, vestibular and auditory information in the maintenance and control of the posture. Method. a search by papers for the last 24 years was done in the PubMed and CAPES databases. The following keywords were used: postural control, sensory information, vestibular system, visual system, somatosensory system, auditory system and haptic system. Results. the influence of each sensory system and its integration were analyzed for the maintenance and control of the posture. Conclusion. the literature showed that there is information redundancy provided by sensory channels. Thus, the central nervous system chooses the main source for the posture control.
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A study was performed to evaluate the influence of mandibular lateral excursion, group function and canine guidance on vestibular cervical dental abfraction (VCDA). Thirty-six individuals of both sexes, aged 20 to 45 years, with full natural dentition with at least one tooth with VCDA were selected at the San Marcos University Clinic. We evaluated number of teeth with VCDA per side (left and right), tooth type and lateral excursive movement (canine guidance or group function) affecting it. The results showed no statistical difference (p > 0.05). The tooth type most often showing VCDA was the first lower premolar, with 30.8% on the right side and 36.4% on the left. Moderate positive correlation was found between age and VCDA (R = 0.40). It is concluded that group function during lateral excursion may contribute to presence of VCDA.
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Canine visceral leishmaniosis (CVL) causes a dependent-stage alteration in neutrophil oxidative metabolism. When production of reactive oxygen species (ROS) exceeds the antioxidant capacity of neutrophils, apoptosis is triggered, impairing the viability and function of these cells, which can predispose dogs to infection. However, the uremic condition observed in late-stage CVL can also alter the viability and function of human neutrophils. To more clearly understand this relationship, the apoptosis rate and oxidative metabolism of neutrophils from control dogs (n= 20) were compared to dogs in moderate (n= 15) and very severe (n= 15) stage CVL, classified according to LeishVet Consensus. To assess neutrophil oxidative metabolism, superoxide production was measured using the nitroblue tetrazolium reduction test (NBT) in isolated neutrophils. The apoptosis rate of neutrophils was estimated using the morphological method. Moderate-stage dogs presented increased superoxide production, while dogs with very severe stage CVL presented decreased superoxide production and an increase neutrophil apoptosis rate. Leishmaniosis causes differential neutrophil dysfunction according to disease stage. In moderate stage CVL, increased superoxide production is observed with no change in neutrophil viability. However, in very severe stage CVL, decreased superoxide production and increased apoptosis occur associated with uremia. © 2013 Elsevier B.V.
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Aims: The renin-angiotensin system (RAS) plays a major role in cardiovascular diseases in postmenopausal women, but little is known about its importance to lower urinary tract symptoms. In this study we have used the model of ovariectomized (OVX) estrogen-deficient rats to investigate the role of RAS in functional and molecular alterations in the urethra and bladder. Main methods: Responses to contractile and relaxant agents in isolated urethra and bladder, as well as cystometry were evaluated in 4-month OVX Sprague-Dawley rats. Angiotensin-converting enzyme activity and Western blotting for AT1/AT2 receptors were examined. Key findings: Cystometric evaluations in OVX rats showed increases in basal pressure, capacity and micturition frequency, as well as decreased voiding pressure. Angiotensin II and phenylephrine produced greater urethral contractions in OVX compared with Sham group. Carbachol-induced bladder contractions were significantly reduced in OVX group. Relaxations of urethra and bladder to sodium nitroprusside and BAY 41-2272 were unaffected by OVX. Angiotensin-converting enzyme activity was 2.6-fold greater (p < 0.05) in urethral tissue of OVX group, whereas enzyme activity in plasma and bladder remained unchanged. Expressions of AT1 and AT2 receptors in the urethra were markedly higher in OVX group. In bladder, AT1 receptors were not detected, whereas AT2 receptor expression was unchanged between groups. 17β-Estradiol replacement (0.1 mg/kg, weekly) or losartan (30 mg/kg/day) largely attenuated most of the alterations seen in OVX group. Significance: Prolonged estrogen deprivation leads to voiding dysfunction and urethral hypercontractility that are associated with increased ACE activity and up-regulation of angiotensin AT1/AT2 receptor in the urethral tissue. © 2013 Elsevier Inc. All rights reserved.
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Pós-graduação em Física - IGCE
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Pós-graduação em Física - IGCE
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Pós-graduação em Linguística e Língua Portuguesa - FCLAR
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Pós-graduação em Pediatria - FMB
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Apresenta o resultado de um estudo sobre a contribuição das estruturas de Tema para a organização da informação em dissertações. Para essa pesquisa, foram utilizados 44 textos produzidos por alunos do Convênio Especial (CE) do extinto sistema de Ensino Elite. Os textos foram divididos em dois grupos: o primeiro grupo (01 – 22) traz textos com média maior que 6,0, e o segundo (23 – 44) textos com média igual ou menor que 6,0. A base teórica assenta-se nos estudos de Halliday (1994), Thompson (1996), Eggins (1994), Neves (1997, 2002), Bakhtin (1992), Marcuschi (1999, 2002), Travaglia (2002), Rojo (2005), Koch (2002, 2006), Souza (2003), Bronckart (2003), Pillar (2002) e Fries (1994). Nos textos analisados, identifico as estruturas de Tema presentes em cada parte do texto (introdução, desenvolvimento e conclusão) e os elementos que formam essas estruturas. Os resultados apontam para o fato de que não há diferença entre os tipos de Temas escolhidos nos dois grupos, mas os elementos temáticos e o método de desenvolvimento diferem. No que diz respeito aos padrões de desenvolvimento, nos textos do primeiro grupo, a maior incidência foi do padrão zig-zag e, nos do segundo grupo, do tema reiterado. A análise dos textos mostra que não é a escolha de determinada estrutura de Tema que garante uma boa organização do texto, mas sim a escolha de qual elemento é escolhido para ocupar a posição temática.
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Analisa quantitativa e qualitativamente a avaliação da compreensão leitora do Espanhol Língua Estrangeira em provas de vestibular da região norte do Brasil, para assim evidenciar os tipos de operações e, dessa maneira, os tipos de modelos de leitura privilegiados nos testes analisados; estabelecer uma relação entre as provas coletadas e as concepções didáticas subjacentes; identificar problemas nos itens das provas com base em uma série de parâmetros de qualidade; analisar a validade dos testes selecionados; e detectar possíveis diferenças entre as provas elaboradas por Instituições de Ensino Superior públicas e privadas. Essa análise evidencia, por um lado, a tendência a se priorizarem, nessas provas, modelos ascendentes de leitura, com valorização das operações cognitivas de baixo nível e de aspectos léxico-gramaticais da língua, como conseqüência de uma concepção didática de leitura baseada em um enfoque estruturalista. Por outro lado, o estudo empreendido mostra a existência de sérias deficiências nos itens das provas de vestibular, afetando assim sua validade.
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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This study aimed at evaluating the effectiveness of partial use of anterior repositioning appliances in the management of TMJ pain and dysfunction when compared to stabilization splints and a control group in a one-year follow-up. Sample was initially constituted by 60 patients, randomly divided into three groups: I- stabilization splints, II- repositioning splints and III- no treatment. The whole sample was evaluated by means of TMJ and muscle palpation, mandibular AROM, analysis of occlusal contacts, joint sounds inspection and Visual Analogue Scale (VAS) for one year; 52 patients composed the final sample. A significant (after 15 days) improvement in pain report (VAS) and palpation index was found for group II (p≤0.01). The occurrence of occlusal alterations as posterior open bite or gross interferences after the splint therapy and increased muscle tenderness were not problems in this study. Similar results in joint noises reduction were observed for the entire sample. It was concluded that controlled partial use of repositioning splints is a beneficial tool in the management of intra-articular pain and dysfunction, with no risks of irreversible occlusal changes.
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The brainstem auditory evoked potential is an electrodiagnostic test that allows a functional assessment of the auditory pathways from the middle ear to the brainstem. This test, in veterinary medicine, is not commonly used in Brazil. This paper reports the use of auditory evoked potential for deafness detection in a cat with unilateral peripheral vestibular syndrome secondary to otitis media.