SU-8 microprobes for biomedical applications

152 p. : il.

Solomons Sketches, Vol. 8 No. 3, Fall 2005: CBL ponders Katrina's aftermath

Articles by faculty: Death by a thousand cuts - Boesch; Revealing the cost of wetland loss - King; Contaminated Waste: an unprecedented disposal problem - Baker; Kay Simkins - volunteer extraordinaire - McGuire; Fisheries likely to revive - Houde; Teachers get hands into Chesapeake Research - Wolf. (PDF contains 6 pages)

Oceanographic Profiling and Spectroradiometer Observations from the MOCE-1 Cruise: 28 August to 8 October 1992

This report contains the frrst observations made for the Modis Optical Characterization Experiment (MOCE). Data presented here were obtained on the R/V DeSteiguer between 28 August and 8 October along the central California coast and in Monterey Bay. Three types of data are reported here: high spectral resolution radiometry at three depths for seven stations; salinity, temperature, fluorescence and beam attenuation profiles at the same stations; and total suspended matter and suspended organic carbon and nitrogen. [PDF contans 164 pages]

Transfer of Medical Sensor Technologies to Environmental Monitoring, Solomons, Maryland, April 6-8, 2005: workshop proceedings

(pdf contains 23 pages)

Legislação sobre o SUS : Lei nº 8.080, de 19 de setembro de 1990 (Lei Orgânica do SUS), que dispõe sobre as condições para a promoção, proteção e recuperação da saúde, a organização e o funcionamento dos serviços correspondentes e dá outras providências, e legislação correlata

Lei nº 8.080, de 19 de setembro de 1990 (Lei Orgânica do SUS), que dispõe sobre as condições para a promoção, proteção e recuperação da saúde, a organização e o funcionamento dos serviços correspondentes e dá outras providências, e legislação correlata. Atualizada até 13/10/2015.

Convergências e divergências acerca do Decreto nº 8.243/2014 : Participação Social

Analisa as controvérsias sobre a Política Nacional de Participação Social (PNPS), mediante a publicação do Decreto 8.243, de 2014.

Generating artificial homologous proteins according to the representative family character in molecular mechanics properties - an attempt in validating an underlying rule of protein evolution

The molecular mechanics property is the foundation of many characters of proteins. Based on intramolecular hydrophobic force network, the representative family character underlying a protein’s mechanics property is described by a simple two-letter scheme. The tendency of a sequence to become a member of a protein family is scored according to this mathematical representation. Remote homologs of the WW-domain family could be easily designed using such a mechanistic signature of protein homology. Experimental validation showed that nearly all artificial homologs have the representative folding and bioactivity of their assigned family. Since the molecular mechanics property is the only consideration in this study, the results indicate its possible role in the generation of new members of a protein family during evolution.

汶川8级地震前加卸载响应比的大尺度异常

孕震初期加卸载响应比(LURR)通常在1左右涨落,然后逐渐上升至峰值点。但强地震并不在峰值点上发生,而要滞后一段时间(T2)。T2与震级有关,震级越大,T2越长。对于8级地震,T2的计算值为28±8个月,汶川8级地震实际的T2是23个月。对于大地震,T2很长,峰值点后LURR通常迅速下降,在大地震前夕LURR常常降得很低,而预测的地震又迟迟没有发生,这种情况下很容易误导人们怀疑,甚至放弃原来的预测,殊不知,这时大地震正在迫近。这正是汶川8级地震给予人们血的教训。大地震不仅孕育时间长,孕震区面积也很大。大地震的前兆在时空上都是大尺度。基于这种认识,根据LURR的演化,中国大陆西南地区可能正在孕育一个特大地震。

Panama City Fisheries Resources Office: FY 2008 Annual Report

HIGHLIGHTS FOR FY 2008 1. Completed the first of a two-year Gulf sturgeon population study on the Choctawhatchee River, Florida. The sub adult and adult Gulf sturgeon population was estimated at 2,800 fish. 2. Gulf sturgeon eggs were collected at three hard bottom sites in the Apalachicola River, Florida; two sites were previously confirmed spawning areas and one was a newly confirmed spawning area. 3. Documented 55 potential environmental threats to Gulf sturgeon spawning habitat in the Pea River, Florida and Alabama. 4. Assigned the Eglin AFB Road-Stream Crossing Working Group to guide the closure, repair and maintenance of roads and road stream crossings that impact threatened and endangered species. 5. Conducted 81 assessments of fish and stream invertebrates on and in watersheds surrounding Eglin AFB. 6. Provided technical support for the 5-year status review and reclassification proposed rule for the Okaloosa darter. 7. Initiated an intensive population genetic analysis of the Okaloosa darter throughout its range. Tissues from over 200 Okaloosa darters were collected and analyzed. 8. Established a GIS database to serve as a host for data from any sites sampled for mussels in Northeast Gulf of Mexico drainages. 9. Conducted habitat surveys at 115 locations in the Apalachicola River to assess the effects of drought-related mussel mortality and strandings, evaluate habitat conditions, and assess population demography. 10. A land use/aerial imagery threats assessment data analysis was completed for the Chipola River. A total of 266 impoundments/borrow pits and 471 unpaved road crossings were identified among the threats. 11. Okaloosa darters marked with elastomeric dyes were monitored in Mill Creek, Eglin AFB, to determine movement and habitat use following completion of a fish passage project. 3 12. Partners for Fish and Wildlife funded a streambank and riparian restoration project on Econfina Creek consisting of 3,900 feet of streambank fencing to exclude cattle access. One acre of riparian floodplain was planted with native trees. 13. We provided design and on-the-ground assistance for restoring surface hydrology at St. Vincent NWR. The project restored approximately 1.5 miles of tidal stream and 100 acres of wetlands. 14. A study was completed on 11 coastal streams to document large wood debris relationships with fluvial geomorphic characteristics. 15. We developed a Population Viability Analysis model for the fat threeridge mussel to determine current and future risk of extinction. 17. A Gulf Sturgeon Friends Group, “Gulf Sturgeon Preservation Society” was organized in FY 08. 18. Multiple outreach projects were completed to detail aquatic resource conservation needs and opportunities, including National Fishing Week, Earth Day, several festivals and school outreach.

IL-8-induced L-selectin shedding regulates its binding kinetics to PSGL-1

L-selectin plays a crucial role in inflammation cascade by initiating the tethering and rolling of leukocytes on endothelium wall. While many L-selectin molecules are rapidly shed from the cell surface upon activation, the remaining membrane-anchored L-selectin may still play an important role in regulating leukocyte rolling and adhesion with different binding kinetics. Here we developed an in vitro model to activate Jurkat cells via interlukin-8 (IL-8) and quantified the two-dimensional (2D) binding kinetics, using a micropipette aspiration assay, of membrane-anchored L-selectin to P-selectin glycoprotein ligand 1 (PSGL-1) ligand coupled onto human red blood cells (RBCs). The data indicated that L-selectin shedding reduced the amount of membrane-anchored L-selectin and lowered both its reverse and forward rates. These results suggested that the rolling dynamics of activated leukocytes was determined by two opposite impacts: reducing the surface presentation would enhance the rolling but lowering the kinetic rates would decrease the rolling. This finding provides a new insight into understanding how L-selectin shedding regulates leukocyte rolling and adhesion.

IL-8刺激L-选择素水解断裂对细胞膜拓扑结构和刚度的影响

目的 研究IL-8刺激所致的L-选择素水解断裂是否会引起细胞膜结构和刚度的变化,进而影响L广选择素-配体的反应动力学.方法 分别用IL-8、TAPI-0+IL-8和TAPI-0处理本构表达L-选择素的Jurkat细胞,用以构建L-选择素水解断裂、阻断水解断裂和阻断剂对照的细胞-分子模型.采用扫描电镜观察其表面拓扑结构,采用微管吸吮方法测量其刚度.结果 与正常组相比,水解断裂组和阻断水解断裂组细胞微绒毛减少、表面趋于光滑,而阻断剂对照组则无明显变化;无论是水解断裂组,阻断水解断裂组还是阻断剂对照组,细胞膜刚度与正常组相比均无显著性差异.结论 IL-8刺激所致L-选择素水解断裂会引发细胞膜拓扑结构的变化,进而影响L一选择素一配体反应动力学的变化;而细胞膜刚度未见明显变化,表明载体刚度不是水解断裂引发L-选择素-配体反应动力学变化的因索.

Rule the World

Rule the World es una aplicación para móviles Android. Consiste en introducir al jugador en una realidad aumentada, mediante el uso de su localización, debe de recoger diferentes objetos para darles diferentes usos, como llevarlos equipados, usarlos para construir otros objetos o enviárselos a amigos. En el siguiente documento se muestra el completo desarrollo de este proyecto, como se ha realizado la gestión, en que partes se ha dividido, la planificación que se ha llevado para realizar el trabajo, el análisis que se hizo de la aplicación, junto con su diseño, como se ha realizado el desarrollo y las pruebas. Este proyecto ha servido para afianzar conocimientos adquiridos a lo largo del grado, como el desarrollo de bases de datos, seguridad y arquitecturas y algoritmos software. Pero también ha servido para aprender nuevas cosas, como programar para un sistema diferente, utilizar elementos poco vistos en el grado, como la geolocalización y los mapas.