Modeling and Analysis of Noise and Interconnects for On-Chip Communication Link Design

This thesis considers modeling and analysis of noise and interconnects in onchip communication. Besides transistor count and speed, the capabilities of a modern design are often limited by on-chip communication links. These links typically consist of multiple interconnects that run parallel to each other for long distances between functional or memory blocks. Due to the scaling of technology, the interconnects have considerable electrical parasitics that affect their performance, power dissipation and signal integrity. Furthermore, because of electromagnetic coupling, the interconnects in the link need to be considered as an interacting group instead of as isolated signal paths. There is a need for accurate and computationally effective models in the early stages of the chip design process to assess or optimize issues affecting these interconnects. For this purpose, a set of analytical models is developed for on-chip data links in this thesis. First, a model is proposed for modeling crosstalk and intersymbol interference. The model takes into account the effects of inductance, initial states and bit sequences. Intersymbol interference is shown to affect crosstalk voltage and propagation delay depending on bus throughput and the amount of inductance. Next, a model is proposed for the switching current of a coupled bus. The model is combined with an existing model to evaluate power supply noise. The model is then applied to reduce both functional crosstalk and power supply noise caused by a bus as a trade-off with time. The proposed reduction method is shown to be effective in reducing long-range crosstalk noise. The effects of process variation on encoded signaling are then modeled. In encoded signaling, the input signals to a bus are encoded using additional signaling circuitry. The proposed model includes variation in both the signaling circuitry and in the wires to calculate the total delay variation of a bus. The model is applied to study level-encoded dual-rail and 1-of-4 signaling. In addition to regular voltage-mode and encoded voltage-mode signaling, current-mode signaling is a promising technique for global communication. A model for energy dissipation in RLC current-mode signaling is proposed in the thesis. The energy is derived separately for the driver, wire and receiver termination.

Spatial variability of noise level in agricultural machines

The knowledge of the spatial variability of noise levels and the build of kriging maps can help the evaluation of the salubrity of environments occupied by agricultural workers. Therefore, the objective of this research was to characterize the spatial variability of the noise level generated by four agricultural machines, using geostatistics, and to verify if the values are within the limits of human comfort. The evaluated machines were: harvester, chainsaw, brushcutter and tractor. The data were collected at the height of the operator's ear and at different distances. Through the results, it was possible to verify that the use of geostatistics, by kriging technique, made it possible to define areas with different levels for the data collected. With exception of the harvester, all of machines presented noise levels above than 85 dB (A) near to the operator, demanding the use of hearing protection.

”AMERICAN ENVIRONMENTS”. Ympäristön merkitykset Don DeLillon romaanissa White Noise

Pro gradu -tutkielmani tavoitteena on analysoida ympäristön merkityksiä yhdysvaltalaiskirjailija Don DeLillon (1936-) romaanissa White Noise (1985). Lähestyn romaania ekokriittisen kirjallisuudentutkimuksen näkökulmasta ja kytken sen ekokriitikko Lawrence Buellin ajatukseen nk. ympäristöalitajunnasta. Analysoin DeLillon romaania myös yhteydessä filosofi Jean Baudrillardin ajatukseen postmodernin ajan länsimaisessa ja erityisesti amerikkalaisessa yhteiskunnassa vallalla olevasta simulaatioiden järjestelmästä. White Noise -romaanin todellisuus vastaa Baudrillardin ajatusta yhteiskunnasta, jossa representaatiot ja simulaatiot ovat korvanneet todellisuuden. Media, erityisesti televisio, tuottaa jatkuvasti kuvia ja simulaatioita, joiden kyllästämässä todellisuudessa aineellinen maailma ja luonto jäävät tavoittamattomiin. White Noise -romaanin henkilöiden yhteys aineelliseen ympäristöönsä ja luonnonilmiöihin on katkennut, sillä heidän arkensa pyörii pitkälti kuluttamisen ja televisionkatselun ympärillä. Romaanin todellisuudessa myös identiteetistä on tullut eräänlainen tuote, jonka jokainen voi rakentaa mieleisekseen kulutusvalinnoillaan. Identiteettiproblematiikan ohella myös kuolemalla on keskeinen asema tutkielmassani. White Noise -romaanin päähenkilö Jack Gladney kärsii paniikinomaisesta kuolemanpelosta, jota pyrkii torjumaan erilaisin keinoin siinä kuitenkaan onnistumatta. Tavoitteenani on osoittaa, että tämä piinaava pelko kuolemaa kohtaan on syntynyt simulaatioyhteiskunnan tuloksena. Vieraantuminen aineellisesta maailmasta ja luonnon prosesseista on johtanut vieraantumiseen ruumiista ja kuolemasta. Analysoin kuolemaa romaanissa eräänlaisena simulaatioiden maailman äärirajana, viimeisenä luonnollisena tapahtumana. White Noise -romaanin päähenkilö Jack Gladney ahdistuu kulutuskeskeisessä, simulaatioiden kyllästämässä elinympäristössään. Tulkitsen tämän ahdistuksen tarpeena tunnistaa tärkeä vuorovaikutussuhde yksilön ja hänen aineellisen ympäristönsä välillä. Jack ei ole vielä täysin sulautunut osaksi simulaatioiden maailmaa, vaan hän tiedostaa kytköksen itsensä ja aineellisen maailman välillä. Tämä romaanista implisiittisesti esiin nouseva tiedostamisen tunne korostaa ihmisen ja ympäristön sekä laajemmin kulttuurin ja luonnon välttämätöntä yhteyttä. DeLillon romaanista on löydettävissä ajatus ympäristöalitajunnasta, joka alleviivaa ympäristön ja luonnon merkitystä ihmiselle.

Noise and vibration damping of Fe-Cr-x alloys

The aim of the present work is to study the noise and vibration damping capacity of ferromagnetic Fe-16%Cr base alloys (before and after heat treatment) with different Al and Mo contents. The noise damping was evaluated by the level of sound emission after an impact. The vibration damping was studied using a cantilever device. In addition to these tests, the magnetic structure of the materials was also investigated by Kerr effect. It was verified that the materials can decrease noise level in the frequency range of human earring. The vibration damping is influenced by heat treatment and chemical composition of the alloy. The improvement of vibration damping after heat treatment is ascribed to the decrease of internal stresses in materials and changes in magnetic domain structures.

Estimating Attractor Dimension on the Nonlinear Pendulum Time Series

Chaotic dynamical systems exhibit trajectories in their phase space that converges to a strange attractor. The strangeness of the chaotic attractor is associated with its dimension in which instance it is described by a noninteger dimension. This contribution presents an overview of the main definitions of dimension discussing their evaluation from time series employing the correlation and the generalized dimension. The investigation is applied to the nonlinear pendulum where signals are generated by numerical integration of the mathematical model, selecting a single variable of the system as a time series. In order to simulate experimental data sets, a random noise is introduced in the time series. State space reconstruction and the determination of attractor dimensions are carried out regarding periodic and chaotic signals. Results obtained from time series analyses are compared with a reference value obtained from the analysis of mathematical model, estimating noise sensitivity. This procedure allows one to identify the best techniques to be applied in the analysis of experimental data.

Exit times for some processes with normally distributed noise

Denna avhandling handlar om metoder för att hitta begränsningar för det asymptotiska beteendet hos en förväntad uthoppstid från ett område omkring en xpunkt för processer som har normalfördelad störning. I huvudsak behandlas olika typer av autoregressiva processer. Fyra olika metoder används. En metod som använder principen för stora avvikelser samt en metod som jämför uthoppstiden med en återkomsttid ger övre begränsningar för den förväntade uthoppstiden. En martingalmetod och en metod för normalfördelade stokastiska variabler ger undre begränsningar. Metoderna har alla både förtjänster och nackdelar. Genom att kombinera de olika metoderna får man de bästa resultaten. Vi får fram gränsvärdet för det asymptotiska beteendet hos en uthoppstid för den multivariata autoregressiva processen, samt motsvarande gränsvärde för den univariata autoregressiva processen av ordning n.

Random amplified polymorphic DNA profiles as a tool for the characterization of Brazilian keratitis isolates of the genus Acanthamoeba

The genus Acanthamoeba comprises free-living amebae identified as opportunistic pathogens of humans and other animal species. Morphological, biochemical and molecular approaches have shown wide genetic diversity within the genus. In an attempt to determine the genetic relatedness among isolates of Acanthamoeba we analyzed randomly amplified polymorphic DNA (RAPD) profiles of 11 Brazilian isolates from cases of human keratitis and 8 American type culture collection (ATCC) reference strains. We found that ATCC strains belonging to the same species present polymorphic RAPD profiles whereas strains of different species show very similar profiles. Although most Brazilian isolates could not be assigned with certainty to any of the reference species, they could be clustered according to pattern similarities. The results show that RAPD analysis is a useful tool for the rapid characterization of new isolates and the assessment of genetic relatedness of Acanthamoeba spp. A comparison between RAPD analyses and morphological characteristics of cyst stages is also discussed.

Eisenbahn-Karte von Europa zu Hendschel's Telegraph

Kartta kuuluu A. E. Nordenskiöldin kokoelmaan

Eisenbahn-Karte von Deutschland zu Hendschel's Telegraph

Kartta kuuluu A. E. Nordenskiöldin kokoelmaan

Eisenbahn-Karte von Europa zu Hendschel's Telegraph

Kartta kuuluu A. E. Nordenskiöldin kokoelmaan

Eisenbahn-Karte von Deutschland zu Hendschel's Telegraph

Kartta kuuluu A. E. Nordenskiöldin kokoelmaan

Random amplification of polymorphic DNA reveals clonal relationships among enteropathogenic Escherichia coli isolated from non-human primates and humans

Enteropathogenic Escherichia coli (EPEC) strains are important agents of infantile diarrhea all over the world, gaining even greater importance in developing countries. EPEC have also been isolated from various animal species, but most isolates belong to serotypes that differ from those recovered from humans. However, it has been demonstrated that several isolates from non-human primates belong to the serogroups and/or serotypes related to those implicated in human disease. The objective of this study was to evaluate the genetic differences between thirteen strains isolated from non-human primates and the same number of strains isolated from human infections. Human isolates belonged to the same serogroup/serotype as the monkey strains and the evaluation was done by analysis of random amplified polymorphic DNA. Dendrogram analysis showed that there was no clustering between human and monkey strains. Human and non-human isolates of the EPEC serotypes O127:H40 and O128:H2 shared 90 and 87% of their bands, respectively, indicating strong genomic similarity between the strains, leading to the speculation that they may have arisen from the same pathogenic clone. To our knowledge, this study is the first one comparing genomic similarity between human and non-human primate strains and the results provide further evidence that monkey EPEC strains correlate with human EPEC, as suggested in a previous investigation.

Effect of scanner acoustic background noise on strict resting-state fMRI

Functional MRI (fMRI) resting-state experiments are aimed at identifying brain networks that support basal brain function. Although most investigators consider a ‘resting-state’ fMRI experiment with no specific external stimulation, subjects are unavoidably under heavy acoustic noise produced by the equipment. In the present study, we evaluated the influence of auditory input on the resting-state networks (RSNs). Twenty-two healthy subjects were scanned using two similar echo-planar imaging sequences in the same 3T MRI scanner: a default pulse sequence and a reduced “silent” pulse sequence. Experimental sessions consisted of two consecutive 7-min runs with noise conditions (default or silent) counterbalanced across subjects. A self-organizing group independent component analysis was applied to fMRI data in order to recognize the RSNs. The insula, left middle frontal gyrus and right precentral and left inferior parietal lobules showed significant differences in the voxel-wise comparison between RSNs depending on noise condition. In the presence of low-level noise, these areas Granger-cause oscillations in RSNs with cognitive implications (dorsal attention and entorhinal), while during high noise acquisition, these connectivities are reduced or inverted. Applying low noise MR acquisitions in research may allow the detection of subtle differences of the RSNs, with implications in experimental planning for resting-state studies, data analysis, and ergonomic factors.

Random-start controlled ovarian stimulation for emergency fertility preservation in a patient with myelodysplastic syndrome: a case report

This study reports a case of a gonadotropin-releasing hormone agonist trigger in a young female with myelodysplastic syndrome (MDS) who underwent fertility preservation using random-start controlled ovarian stimulation. This method involves the stimulation of the ovary regardless of a patient's menstrual-cycle phase. A review of the related literature is also provided. A 17-year-old patient was diagnosed with MDS and required initiation of peripheral blood stem cell transplantation within a maximum of 3 weeks and was in the luteal phase of the menstrual cycle when the possibility of attempting preservation of fertility was presented to her. She opted for a random-start controlled ovarian stimulation with gonadotropins. With successful hemorrhagic prophylaxis, 17 oocytes were retrieved including 10 mature and 7 immature oocytes. Of the immature oocytes, 3 were successfully matured in vitro and a vitrification protocol was used to freeze the 13 mature oocytes.

Optimization of random amplified polymorphic DNA protocol for molecular identification of Lophius gastrophysus

Lophius gastrophysus has important commercial value in Brazil particularly for foreign trade. In this study, we described the optimization of Random Amplified Polymorphic DNA (RAPD) protocol for identification of L. gastrophysus. Different conditions (annealing temperatures, MgCl concentrations, DNA quantity) were tested to find reproducible and adequate profiles. Amplifications performed with primers A01, ² A02 and A03 generate the best RAPD profiles when the conditions were annealing temperature of 36ºC, 25 ng of DNA quantity and 2.5 mM MgCl2. Exact identification of the species and origin of marine products is necessary and RAPD could be used as an accurate, rapid tool to expose commercial fraud.