911 resultados para Presentation Objectives


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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em Educação - FFC

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O linfoma de células natural killers (NK)/T extranodal é um tumor maligno agressivo com características clinicopatológicas distintas, caracterizadas por invasão e destruição vasculares, necrose proeminente, fenótipo linfocítico citotóxico e uma forte associação com o vírus Epstein-Barr. Relatamos aqui um caso de linfoma de células NK/T nasal extranodal, envolvendo o seio maxilar, assoalho de órbita, e interessantemente estendendo-se para a cavidade oral através do osso alveolar e mucosa vestibular, preservando o palato, levando a um diagnóstico inicial equivocado de doença periodontal agressiva. Ainda, nós investigamos pela primeira vez a expressão imunoistoquímica das proteínas Fatty acid sinthase (FASN) e glucose transporter 1 (GLUT-1) nesta neoplasia. FASN revelou uma forte expressão citoplasmática nas células neoplásicas, enquanto GLUT-1 e CD44 foram negativas. Estes achados sugerem que a expressão de FASN e a perda de CD44 podem estar envolvidas na patogênese do linfoma de células NK/T nasal extranodal, e que GLUT-1 não deve participar da adaptação das células tumorais ao ambiente de hipóxia. Estudos adicionais com séries maiores são necessários para confirmar nossos resultados iniciais.

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Graft-versus-host disease is observed mainly in recipients of hematopoietic cell transplantation and is expressed by cutaneous or systemic signals and symptoms. Graft-versus-host disease is clinically classified as acute or chronic. Chronic Graft-versus-host disease occurs in up to 70% of hematopoietic cell transplanted patients and its clinical manifestations have important impact on morbidity and quality of life. The authors report an expressive cutaneous, oral and adnexal involvement in a patient with chronic Graft-versus-host disease with multiple lesions of lichenoid and atrophic pattern.

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Pós-graduação em Agronomia (Ciência do Solo) - FCAV

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Literature is a treasure for humanity and for the school. It causes psychological function of the individual, inserts it in the context of various cultures and historic moments, and, by having formative nature, School and Literature are intrinsecally related institutions. But literature is not the end of the first teaching, while the school has the purpose of teaching literature. Literature is not a source of good leads standards; have to be educated without this process to misrepresent. Thus, it was estalished is to investigate the inadequacy of schooling of Children's Literature pointed out by Soares in 2006, is still reality that becomes present in school or if there was any change in that status. Specific objectives were established: 1)Scanning separately in each of the books education system, from first to fifth grade of elementary school, according to the following categories involving education of literary reading: selection of genres and authors; presentation of these genres and no change from one genre to another; 2)analyze the way children's literature is presented by note-books analyzed education system develop the sensitivity of the student for pluris-signification and expressiveness of literary language, while fulfilling its social function and knowledge; 3)review the comprehension activities of literary reading proposed by notebooks to seize their educational goals. Therefore, we carried out basic theoretical research, demonstrating the functions of literature and the teaching of literature in school, and documentary research. Were analyzed 20 documents (the system apostilled notebooks), paying attention to classwork it to him of genres, authors and works chosen to be worked out, observing the cases of texts fragmentation and transport the genre to the page of the notebook system apostilled, and investigating the goals of literary reading instruction through the analysis of comprehension activities. The data received quantitative...

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Pós-graduação em Ciências Sociais - FFC

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Background: Human fungal infections have increased at an alarming rate in recent years, particularly in immunocompromised individuals. Cryptococcosis is the second most prevalent systemic fungal infection worldwide, and the most prevalent systemic infection in immunocompromised individuals, representing more than 70% of cases. The incidence of cryptococcosis is high in people with HIV/acquired immunodefi- ciency syndrome (AIDS), with recent estimates indicating that there are one million cases of cryptococcal meningitis globally per year in AIDS patients. Aims: The aim of this research was to develop a rapid flow cytometric antifungal susceptibility test and to compare the results with the standard methods. Methods: A reference strain and clinical isolates of Cryptococcus neoformans and Cryptococcus gattii were tested for susceptibility to amphotericin B by flow cytometry using propidium iodide as indicator of viability. Flow cytometry (FC) results were compared with the minimum inhibitory concentration (MIC) values determined by microdilution. Results: The antifungal activity of amphotericin B ranged from MICs of 0.06 to 2 g/ml for the 11 isolates studied. The same results were found by FC. Conclusions: The FC method allows same-day results, assisting in the selection of appropriate antifungal therapies. These results demonstrate an excellent correlation between FC and the classic methods of testing for susceptibility to antifungal agents. This rapid diagnosis method makes it possible to quickly administer effective therapeutic interventions, often saving lives.