616 resultados para Metabólitos fecais de glicocorticóides


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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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The use of medicinal plants is common in many Brazil's ethnic groups, because the diversity of plant species in the country is large. But the utilization of these plants as standardized herbal doesn't occur with de same frequency, due the lack of studies related to these therapies, classified as alternatives. Due to the high cost of some synthetic medicines for the treatment of chronic diseases, phytotherapy is a low-cost alternative and efficient, since the phytomedication has proven scientific studies and its production meets strict criteria for manufacturing and quality control to ensure its safety and efficacy. Among the medicinal species used for the treatment of chronic diseases, such as pain and inflammation, is Eugenia speciosa Cambess, popularly known as the bush laranjinha. Against this context, this paper held preliminary studies and developed the chromatographic profile of the hydroalcoholic extract of the leaves of E. speciosa by High Performance Liquid Chromatography coupled to photodiode array detector (CLAE-DAD). Preliminary qualitative results and the chromatographic profile have identified some metabolites classes present and some constituent as: homogentisic acid, homorientina, isovitexin and quercetrin

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Research on natural products is extremely important either for new compound discovery with possible pharmacology uses or for its impact on economy, which moves millions of dollars for year. Scientific studies related on utilization and characterization of bioactive substances are important due to the fact that many drugs currently used by the population were synthetized from isolated compounds of natural products. Among many medicinal species commonly used, there are that ones from the genus Eugenia, witch belongs to Myrtaceae family. Eugenia is one of the biggest genus from this family and has about 5000 species and Brazil has 400 of them, which are appreciated on gastronomy for its fruits, for example, pitanga (Eugenia uniflora), cherry (Eugenia involucrata), clove (Eugenia caryophyllata) and cagaita (Eugenia dysinterica). Phytochemical studies of plants from this genus report the presence of several secondary metabolites like flavonoids, tannins, coumarins, anthocyanins and more. Eugenia species have important pharmacology activity as antioxidant, hypothermic, antidiarrheal, antihypertensive, antimicrobial and fungicide. Thus, Eugenia is a genus which has species with potencial phytotherapic products

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Pós-graduação em Medicina Veterinária - FCAV

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A água é um recurso vital para a existência de todos os organismos vivos, e a captação para uso doméstico, produção agrícola, mineração, produção industrial, geração de energia, atividades de lazer e práticas florestais podem levar à deterioração da sua qualidade, atingindo o ecossistema aquático e também a disponibilidade de água potável disponível para consumo humano. O presente trabalho teve como objetivo monitorar a qualidade da água do Córrego Chumbeadinha no município de Ourinhos-SP, que perpassa pela área urbana da cidade e é desprovido de mata ciliar em quase todo seu percurso, além de sofrer dois represamentos artificiais. O Córrego Chumbeadinha é um afluente de segunda ordem do Rio Paranapanema, percorrendo cerca 4 km de sua nascente até sua foz. Foram realizadas amostragens das seguintes variáveis: Sólidos em Suspensão, pH, concentração de oxigênio dissolvido, condutividade elétrica, temperatura da água, coliformes fecais, transparência da água, além do cálculo do índice de estado trófico, em quatro locais no curso do córrego, de setembro de 2009 a abril de 2010. Dessa forma, o córrego Chumbeadinha nasce com uma qualidade boa, apesar de sofrer forte pressão da expansão urbana, porém os demais pontos foram classificados como eutróficos, sendo registrada a presença de coliformes fecais em todas as amostragens. A falta de vegetação nas margens do lago pode ser a grande causadora da eutrofização, pois os sedimentos não encontram dificuldades para chegar até o curso d'água, assim interferindo diretamente no IET do lago.

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Milk that is adequate for consumption must be of hygienic quality, nutritional value, and should maintain its organoleptic properties. Isolation of fecal and/or total coliforms from bovine milk is considered an indicator of hygiene and good management practices, and can be used as a quality indicator. This study aimed to isolate, identify, and assess the resistance profile of coliforms isolated from collective bulk tanks and individual milk tanks. A total of 89 milk samples were collected from collective bulk tanks and, from these, 21 Klebsiella spp., one E. coli, and 29 Enterobacter spp. were isolated, whereas 102 milk samples from individual tanks showed isolation of one Klebsiella spp. and seven Enterobacter spp. In collective bulk tanks, at least 47% of Klebsiella spp. and Enterobacter spp. were resistant to cephalexin and 30% to ampicillin. From these, at least 24% showed multidrug resistance. Among the microorganisms isolated from the individual tanks, 85% or more were resistant to ampicillin. The ESBL phenotype and the blaTEM gene were detected in strains of Klebsiella spp. isolated from both tanks. It was concluded that contamination of milk with resistant total coliforms, and especially the storage of raw milk from several small producers in the collective bulk tank increase the risk of contamination.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em Química - IQ