Between the rose and the shoulders of giants

The following are thoughts on 2 of the most well-known phrases in the English language, recognized as universal academic icons. That of Juliet Capuleto’s in Act II, scene II, “The Balcony”, in the immortal work of William shakespeare’s Romeo and Juliet about “A rose by any other name”, and “On the shoulders of giants”, traditionally attributed to Isaac Newton, the discoverer of the Mechanical Universal Laws, including that of Universal Law of Gravitation, in the 17th Century, but in reality first said by the humanistic philosopher and theologist Bernard of Chartres in the 12th Century

An updated evolutionary classification of CRISPR–Cas systems

The evolution of CRISPR–cas loci, which encode adaptive immune systems in archaea and bacteria, involves rapid changes, in particular numerous rearrangements of the locus architecture and horizontal transfer of complete loci or individual modules. These dynamics complicate straightforward phylogenetic classification, but here we present an approach combining the analysis of signature protein families and features of the architecture of cas loci that unambiguously partitions most CRISPR–cas loci into distinct classes, types and subtypes. The new classification retains the overall structure of the previous version but is expanded to now encompass two classes, five types and 16 subtypes. The relative stability of the classification suggests that the most prevalent variants of CRISPR–Cas systems are already known. However, the existence of rare, currently unclassifiable variants implies that additional types and subtypes remain to be characterized.

A gravitação da ética do cuidado na mediação : intervenção social e escolar nas escolas

Na resolução de conflitos, no incumprimento de normas e nas situações de indisciplina escolar, exigem-se mediadores e programas de mediação. Na implementação destes programas é essencial formar mediadores para intervirem em contexto socioeducativo com alunos, professores e família, sendo exigido a esses profissionais uma ética profissional mediadora. A necessidade de educar os alunos para integrarem as equipes de mediação implica a promoção de valores de convivência e uma ética do cuidado com os outros. A ética do cuidado e do encontro permite mais possibilidades de convívio e novas formas de existência humana. Procuramos interpretar os pontos de vista de alguns autores sobre a mediação (modelos e programas), destacando a educação para a tolerância, solidariedade, responsabilidade e cidadania, que são exigências da escola no âmbito da educação para os valores. A mediação contribui para resolver conflitos, melhorar a comunicação, as relações e a convivência.