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Aquest qüestionari pretén valorar l’experiència dels estudiants dins del projecte d’Aprenentatge i Servei que promous. El qüestionari és confidencial i no trigaràs més de 15 minuts en respondre'l.

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Aquest qüestionari pretén valorar l’experiència dels estudiants dins del projecte d’Aprenentatge i Servei que promous. El qüestionari és confidencial i no trigaràs més de 15 minuts en respondre'l.

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Aquest qüestionari pretén valorar la teva experiència en la participació del projecte que desenvolupes en la universitat. El qüestionari és anònim i no trigaràs més de 15 minuts en respondre'l.

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Aquest qüestionari pretén valorar la teva experiència en la participació del projecte que desenvolupes en la universitat. El qüestionari és anònim i no trigaràs més de 15 minuts en respondre'l.

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Aquest qüestionari pretén valorar l’experiència dels estudiants dins del projecte d’Aprenentatge i Servei que promous. El qüestionari és confidencial i no trigaràs més de 15 minuts en respondre'l.

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Aquest qüestionari pretén valorar la teva experiència en la participació del projecte que desenvolupes en la universitat. El qüestionari és anònim i no trigaràs més de 15 minuts en respondre'l.

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Aquest qüestionari pretén valorar l’experiència dels estudiants dins del projecte d’Aprenentatge i Servei que promous. El qüestionari és confidencial i no trigaràs més de 15 minuts en respondre'l.

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Aquest qüestionari pretén valorar l’experiència dels estudiants dins del projecte d’Aprenentatge i Servei que promous. El qüestionari és confidencial i no trigaràs més de 15 minuts en respondre'l.

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Aquest qüestionari pretén valorar l’experiència dels estudiants dins del projecte d’Aprenentatge i Servei que promous. El qüestionari és confidencial i no trigaràs més de 15 minuts en respondre'l.

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Aquest qüestionari pretén valorar l’experiència dels estudiants dins del projecte d’Aprenentatge i Servei que promous. El qüestionari és confidencial i no trigaràs més de 15 minuts en respondre'l.

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Aquest qüestionari pretén valorar l’experiència dels estudiants dins del projecte d’Aprenentatge i Servei que promous. El qüestionari és confidencial i no trigaràs més de 15 minuts en respondre'l.

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The RAD52 epistasis group was identified in yeast as a group of genes required to repair DNA damaged by ionizing radiation [1]. Genetic evidence indicates that Rad52 functions in Rad51-dependent and Rad51-independent recombination pathways [2] [3] [4]. Consistent with this, purified yeast and human Rad52 proteins have been shown to promote single-strand DNA annealing [5] [6] [7] and to stimulate Rad51-mediated homologous pairing [8] [9] [10] [11]. Electron microscopic examinations of the yeast [12] and human [13] Rad52 proteins have revealed their assembly into ring-like structures in vitro. Using both conventional transmission electron microscopy and scanning transmission electron microscopy (STEM), we found that the human Rad52 protein forms heptameric rings. A three-dimensional (3D) reconstruction revealed that the heptamer has a large central channel. Like the hexameric helicases such as Escherichia coli DnaB [14] [15], bacteriophage T7 gp4b [16] [17], simian virus 40 (SV40) large T antigen [18] and papilloma virus E1 [19], the Rad52 rings show a distinctly chiral arrangement of subunits. Thus, the structures formed by the hexameric helicases may be a more general property of other proteins involved in DNA metabolism, including those, such as Rad52, that do not bind and hydrolyze ATP.

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PURPOSE: To study prospectively the success rate and complications of deep sclerectomy with collagen implant (DSCI). SETTING: Glaucoma Unit, Department of Ophthalmology, Hôpital Ophtalmique Jules Gonin, University of Lausanne, Lausanne, Switzerland. METHODS: This nonrandomized prospective trial comprised 105 eyes of 105 patients with medically uncontrolled primary and secondary open-angle glaucoma. Visual acuity, intraocular pressure (IOP), and slitlamp examinations were performed before surgery and after surgery at 1 and 7 days, and 1, 3, 6, 9, 12, 18, 24, 30, 36, 48, 54, 60, 66, 72, 78, 84, 90, and 96 months. Visual field examinations were repeated every 6 months. RESULTS: Mean follow-up period was 64 months +/- 26.6 (SD). Mean preoperative IOP was 26.8 +/- 7.7 mm Hg, and mean postoperative IOP was 5.2 +/- 3.35 mm Hg at day 1 and 12 +/- 3 mm Hg at month 78. At 96 months, the qualified success rate (ie, patients who achieved IOP <21 mm Hg with and without medication) was 91%, and the complete success rate (ie, IOP <21 mm Hg without medication) was 57%. At 96 months, 34% of patients had an IOP <21 mm Hg with medication. Fifty-one patients (49%) achieved an IOP < or =15 mm Hg without medication. Neodymium:YAG goniopuncture was performed in 54 patients (51%); mean time of goniopuncture performance was 21 months, and mean IOP before goniopuncture was 20 mm Hg, dropping to 11 mm Hg after goniopuncture. No shallow or flat anterior chamber, endophthalmitis, or surgery-induced cataract was observed. However, 26 patients (25%) showed a progression of preexisting senile cataract (mean time 26 months; range 18 to 37 months). Injections of 5-fluorouracil were administered to 25 patients (23%) who underwent DSCI to salvage encysted blebs. Mean number of medications per patient was reduced from 2.3 +/- 0.7 to 0.5 +/- 0.7 (signed rank P<.0001). CONCLUSION: Deep sclerectomy with collagen implant appears to provide stable and reasonable control of IOP at long-term follow-up with few immediate postoperative complications.

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Autopsy-negative sudden cardiac deaths (SCD) seen in forensic practice are most often thought to be the result of sudden arrhythmic death syndrome. Postmortem genetic analysis is recommended in such cases, but is currently performed in only a few academic centers. In order to determine actual current practice, an on-line questionnaire was sent by e-mail to members of various forensic medical associations. The questions addressed routine procedures employed in cases of sudden cardiac death (autopsy ordering, macroscopic and microscopic cardiac examination, conduction tissue examination, immunohistochemistry and electron microscopy, biochemical markers, sampling and storage of material for genetic analyses, toxicological analyses, and molecular autopsy). Some questions concerned the legal and ethical aspects of genetic analyses in postmortem examinations, as well as any existing multidisciplinary collaborations in SCD cases. There were 97 respondents, mostly from European countries. Genetic testing in cases of sudden cardiac death is rarely practiced in routine forensic investigation. Approximately 60% of respondents reported not having the means to perform genetic postmortem testing and 40% do not collect adequate material to perform these investigations at a later date, despite working at university hospitals. The survey demonstrated that many of the problems involved in the adequate investigation of SCD cases are often financial in origin, due to the fact that activities in forensic medicine are often paid by and dependent on the judicial authorities. Problems also exist concerning the contact with family members and/or the family doctor, as well as the often-nonexistent collaboration with others clinicians with special expertise beneficial in the investigation of SCD cases, such as cardiologists and geneticists. This study highlights the importance in establishing guidelines for molecular autopsies in forensic medicine.

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This questionnaire aims to evaluate your experience of taking part in the project you are carrying out at the university. The questionnaire is anonymous and will not take more than 10 minutes of your time to complete. We would appreciate your honest opinion, in order that the data we gather here can be as useful as possible for improving the project.