Techniques for Estimating Flood-Frequency Discharges for Streams in Iowa, HR-395A, 2001

A statewide study was conducted to develop regression equations for estimating flood-frequency discharges for ungaged stream sites in Iowa. Thirty-eight selected basin characteristics were quantified and flood-frequency analyses were computed for 291 streamflow-gaging stations in Iowa and adjacent States. A generalized-skew-coefficient analysis was conducted to determine whether generalized skew coefficients could be improved for Iowa. Station skew coefficients were computed for 239 gaging stations in Iowa and adjacent States, and an isoline map of generalized-skew-coefficient values was developed for Iowa using variogram modeling and kriging methods. The skew map provided the lowest mean square error for the generalized-skew- coefficient analysis and was used to revise generalized skew coefficients for flood-frequency analyses for gaging stations in Iowa. Regional regression analysis, using generalized least-squares regression and data from 241 gaging stations, was used to develop equations for three hydrologic regions defined for the State. The regression equations can be used to estimate flood discharges that have recurrence intervals of 2, 5, 10, 25, 50, 100, 200, and 500 years for ungaged stream sites in Iowa. One-variable equations were developed for each of the three regions and multi-variable equations were developed for two of the regions. Two sets of equations are presented for two of the regions because one-variable equations are considered easy for users to apply and the predictive accuracies of multi-variable equations are greater. Standard error of prediction for the one-variable equations ranges from about 34 to 45 percent and for the multi-variable equations range from about 31 to 42 percent. A region-of-influence regression method was also investigated for estimating flood-frequency discharges for ungaged stream sites in Iowa. A comparison of regional and region-of-influence regression methods, based on ease of application and root mean square errors, determined the regional regression method to be the better estimation method for Iowa. Techniques for estimating flood-frequency discharges for streams in Iowa are presented for determining ( 1) regional regression estimates for ungaged sites on ungaged streams; (2) weighted estimates for gaged sites; and (3) weighted estimates for ungaged sites on gaged streams. The technique for determining regional regression estimates for ungaged sites on ungaged streams requires determining which of four possible examples applies to the location of the stream site and its basin. Illustrations for determining which example applies to an ungaged stream site and for applying both the one-variable and multi-variable regression equations are provided for the estimation techniques.

Satisfaction survey with DNA cards method to collect genetic samples for pharmacogenetics studies

Background: Pharmacogenetic studies are essential in understanding the interindividual variability of drug responses. DNA sample collection for genotyping is a critical step in genetic studies. A method using dried blood samples from finger-puncture, collected on DNA-cards, has been described as an alternative to the usual venepuncture technique. The purpose of this study is to evaluate the implementation of the DNA cards method in a multicentre clinical trial, and to assess the degree of investigators' satisfaction and the acceptance of the patients perceived by the investigators.Methods: Blood samples were collected on DNA-cards. The quality and quantity of DNA recovered were analyzed. Investigators were questioned regarding their general interest, previous experience, safety issues, preferences and perceived patient satisfaction. Results: 151 patients' blood samples were collected. Genotyping of GST polymorphisms was achieved in all samples (100%). 28 investigators completed the survey. Investigators perceived patient satisfaction as very good (60.7%) or good (39.3%), without reluctance to finger puncture. Investigators preferred this method, which was considered safer and better than the usual methods. All investigators would recommend using it in future genetic studies. Conclusion: Within the clinical trial setting, the DNA-cards method was very well accepted by investigators and patients (in perception of investigators), and was preferred to conventional methods due to its ease of use and safety.

Highway Applications for Rammed Aggregate Piers in Iowa Soils, TR-443, 2003

This report describes a study to evaluate Geopier® soil reinforcement technology in transportation construction. Three projects requiring settlement control were chosen for evaluation—an embankment foundation, a box culvert, and a bridge approach fill. For each project, construction observations, in situ soil testing, laboratory material characterization, and performance monitoring were carried out. For the embankment foundation project, Geopier elements were installed within and around an abutment footprint for the new I-35 overpass at the US Highway 5/Interstate 35 interchange in Des Moines, Iowa. Although the main focus of this investigation was to evaluate embankment foundation reinforcement using Geopier elements, a stone column reinforced soil provided an opportunity to compare systems. In situ testing included cone penetration tests (CPTs), pressuremeter tests (PMTs), Ko stepped blade tests, and borehole shear tests (BSTs), as well as laboratory material testing. Comparative stiffness and densities of Geopier elements and stone columns were evaluated based on full-scale modulus load tests and standard penetration tests. Vibrating wire settlement cells and total stress cells were installed to monitor settlement and stress concentration on the reinforcing elements and matrix soil. Settlement plates were also monitored by conventional optical survey methods. Results show that the Geopier system and the stone columns performed their intended functions. The second project involved settlement monitoring of a 4.2 m wide x 3.6 m high x 50 m long box culvert constructed beneath a bridge on Iowa Highway 191 south of Neola, Iowa. Geopier elements were installed to reduce total and differential settlement while ensuring the stability of the existing bridge pier foundations. Benefits of the box culvert and embankment fill included (1) ease of future roadway expansion and (2) continual service of the roadway throughout construction. Site investigations consisted of in situ testing including CPTs, PMTs, BSTs, and dilatometer tests. Consolidated drained triaxial compression tests, unconsolidated undrained triaxial compression test, oedometer tests, and Atterberg limit tests were conducted to define strength and consolidation parameters and soil index properties for classification. Vibrating wire settlement cells, total stress cells, and piezometers were installed for continuous monitoring during and after box culvert construction and fill placement. This project was successful at controlling settlement of the box culvert and preventing downdrag of the bridge foundations, but could have been enhanced by reducing the length of Geopier elements at the ends of the box culvert. This would have increased localized settlement while reducing overall differential settlement. The third project involved settlement monitoring of bridge approach fill sections reinforced with Geopier elements. Thirty Geopier elements, spaced 1.8 m apart in six rows of varying length, were installed on both sides of a new bridge on US Highway 18/218 near Charles City, Iowa. Based on the results of this project, it was determined that future applications of Geopier soil reinforcement should consider extending the elements deeper into the embankment foundation fill, not just the fill itself.

Final Report (SPR Project 90-00-RB10-012) on the Maintenance Asset Management Project Phase I, 2012

This project resulted in the development of a proof of concept for a features inventory process to be used by field staff. The resulting concept is adaptable for different asset classes (e.g. culverts, guardrail) and able to leverage existing DOT resources such as the videolog and LRS and our current technology platforms including Oracle and our GIS web infrastructure. The concept examined the feasibility of newly available technologies, such as mobile devices, while balancing ease of use in the field. Implementation and deployment costs were also important considerations in evaluating the success of the project. These project funds allowed the pilot to address the needs of two DOT districts. A report of findings was prepared, including recommendations for or against full deployment of the pilot solution.

Final Report (SPR Project 90-00-RB10-012) on the Maintenance Asset Management Project Phase II, 2013

This project resulted in the development of a proof of concept for a features inventory process to be used by field staff. The resulting concept is adaptable for different asset classes (e.g. culverts, guardrail) and able to leverage existing DOT resources such as the videolog and LRS and our current technology platforms including Oracle and our GIS web infrastructure. The concept examined the feasibility of newly available technologies, such as mobile devices, while balancing ease of use in the field. Implementation and deployment costs were also important considerations in evaluating the success of the project. These project funds allowed the pilot to address the needs of two DOT districts. A report of findings was prepared, including recommendations for a full deployment of a field data collection.

Free-breathing whole-heart coronary MRA with 3D radial SSFP and self-navigated image reconstruction.

Respiratory motion is a major source of artifacts in cardiac magnetic resonance imaging (MRI). Free-breathing techniques with pencil-beam navigators efficiently suppress respiratory motion and minimize the need for patient cooperation. However, the correlation between the measured navigator position and the actual position of the heart may be adversely affected by hysteretic effects, navigator position, and temporal delays between the navigators and the image acquisition. In addition, irregular breathing patterns during navigator-gated scanning may result in low scan efficiency and prolonged scan time. The purpose of this study was to develop and implement a self-navigated, free-breathing, whole-heart 3D coronary MRI technique that would overcome these shortcomings and improve the ease-of-use of coronary MRI. A signal synchronous with respiration was extracted directly from the echoes acquired for imaging, and the motion information was used for retrospective, rigid-body, through-plane motion correction. The images obtained from the self-navigated reconstruction were compared with the results from conventional, prospective, pencil-beam navigator tracking. Image quality was improved in phantom studies using self-navigation, while equivalent results were obtained with both techniques in preliminary in vivo studies.

Iowa Cultural Leadership Partners 2013 Interview Highlights, September 2013

The Cultural Leadership Partners Program of the Iowa Arts Council and Iowa Department of Cultural Affairs (IAC/DCA) engages leaders in Iowa’s arts and cultural community that have demonstrated an exemplary record of programming and managerial excellence, as well as exceptional community service to the citizens of Iowa on a year-round basis. After a rigorous application process, organizations selected to become Cultural Leadership Partners (CLPs) receive annual operating support from IAC/DCA. This document will not only serve to communicate to CLPs what the IAC/DCA has learned from these conversations, but that it will act as a catalyst for further development of the program and inform how IAC/DCA can support, challenge, connect, and partner with Iowa’s leading arts and cultural institutions.

Non-viral ocular gene therapy: potential ocular therapeutic avenues.

Non-viral vectors for potential gene replacement and therapy have been developed in order to overcome the drawbacks of viral vectors. The diversity of non-viral vectors allows for a wide range of various products, flexibility of application, ease of use, low-cost of production and enhanced "genomic" safety. Using non-viral strategies, oligonucleotides (ODNs) can be delivered naked (less efficient) or entrapped in cationic lipids, polymers or peptides forming slow release delivery systems, which can be adapted according to the organ targeted and the therapy purposes. Tissue and cell internalization can be further enhanced by changing by physical or chemical means. Moreover, a specific vector can be selected according to disease course and intensity of manifestations fulfilling specific requirements such as the duration of drug release and its level along with cells and tissues specific targeting. From accumulating knowledge and experience, it appears that combination of several non-viral techniques may increase the efficacy and ensure the safety of these evolving and interesting gene therapy strategies.

Monipolttoainekattilan päästöjen tarkkailu ja raportointi

Suurten polttolaitosten päästöjen tarkkailu- ja raportointivaatimukset ovat uudistuneet viime vuosina paljon. Suurimpia muutosten aiheuttajia ovat Valtioneuvoston asetus 1017/2002 ja standardi EN-14181. Tässä työssä kuvataan uudet vaatimukset täyttävän päästöjen tarkkailu- ja raportointijärjestelmän rakentaminen monipolttoainekattilalle. Aluksi esitellään mitä uusia vaatimuksia päästöjen tarkkailulle ja raportoinnille on tullut viime aikoina. Lisäksi selvitetään vaatimusten mahdolliset ristiriidat ja ristiriitatilanteiden ratkaisutavat. Seuraavaksi esitellään vaatimukset täyttävän järjestelmän määritelmät. Erityisestiselvitetään kattilan erityispiirteiden vaatimia ratkaisuja. Lopuksi esitellään päästöjen tarkkailu- ja raportointijärjestelmän käyttökokemuksia ja parantamismahdollisuuksia. Kaikki tarkastelut tehdään ensisijaisesti toiminnanharjoittajan näkökulmasta. Järjestelmä toteutettiin Stora Enso Oyj:n Heinolan Flutingtehtaan voimalaitoksen pääkattilalle, jossa käytetään laajaa polttoainevalikoimaa. Toteutuspaikan valinta tehtiin sillä perusteella, että uudet päästöjen tarkkailu- ja raportointivaatimukset ovat erityisen haasteellisia monipolttoainekattiloiden tapauksessa. Työssä selvitetään järjestelmän soveltamismahdollisuuksia myös kahdella muulla Stora Enson tehtaalla. Käyttöönottovaiheen johtopäätöksenä todettiin päästöjen tarkkailu- ja raportointijärjestelmän täyttävän sille asetetut vaatimukset. Lisäksi havaittiin, että toiminnanharjoittajan kannattaa panostaa erityisesti järjestelmän joustavuuteen, luotettavuuteen, helppokäyttöisyyteen ja vikasietoisuuteen. Toiminnanharjoittaja pystyy määrittelyvaiheessa vaikuttamaan järjestelmän ominaisuuksiin helpommin ja edullisemmin kuin käyttöönoton jälkeen. Toiminnanharjoittajalta vaadittu työtuntimäärä arvioitiin Heinolan Flutingtehtaan tapauksen perusteella. Lopuksi selvitettiin mahdollisia tulevaisuuden kehityskohteita vastaavissa järjestelmissä.

Electric bicycles as a new active transportation modality to promote health.

GOJANOVIC, B., J. WELKER, K. IGLESIAS, C. DAUCOURT, and G. GREMION. Electric Bicycles as a New Active Transportation Modality to Promote Health. Med. Sci. Sports Exerc., Vol. 43, No. 11, pp. 2204-2210, 2011. Electrically assisted bicycles (EAB) are an emerging transportation modality favored for environmental reasons. Some physical effort is required to activate the supporting engine, making it a potential active commuting option. Purpose: We hypothesized that using an EAB in a hilly city allows sedentary subjects to commute comfortably, while providing a sufficient effort for health-enhancing purposes. Methods: Sedentary subjects performed four different trips at a self-selected pace: walking 1.7 km uphill from the train station to the hospital (WALK), biking 5.1 km from the lower part of town to the hospital with a regular bike (BIKE), or EAB at two different power assistance settings (EAB(high), EAB(std)). HR, oxygen consumption, and need to shower were recorded. Results: Eighteen sedentary subjects (12 female, 6 male) age 36 +/- 10 yr were included, with (V) over dotO(2max) of 39.4 +/- 5.4 mL.min(-1).kg(-1). Time to complete the course was 22 (WALK), 19 (EAB(high)), 21 (EAB(std)), and 30 (BIKE) min. Mean %(V) over dotO(2max) was 59.0%, 54.9%, 65.7%, and 72.8%. Mean%HR(max) was 71.5%, 74.5%, 80.3%, and 84.0%. There was no significant difference between WALK and EAB(high), but all other comparisons were different (P < 0.05). Two subjects needed to shower after EAB(high), 3 needed to shower after WALK, 8 needed to shower after EAB(std), and all 18 needed to shower after BIKE. WALK and EAB(high) elicited 6.5 and 6.1 METs (no difference), whereas it was 7.3 and 8.2 for EAB(std) and BIKE. Conclusions: EAB is a comfortable and ecological transportation modality, helping sedentary people commute to work and meet physical activity guidelines. Subjects appreciated ease of use and mild effort needed to activate the engine support climbing hills, without the need to shower at work. EAB can be promoted in a challenging urban environment to promote physical activity and mitigate pollution issues.

Kiinteistön ohjaus- ja valvontajärjestelmän toteutus mobiiliympäristöön

Ohjelmistoprojektin läpivienti vaatii suunnittelua ja yhteisiä tapaamisia toimittajan ja asiakkaan kesken. Ohjelmistotuotannon prosessit ovat määrittely, suunnittelu, toteutus, testaus ja käyttöönotto. Tärkeimmät dokumentit ovat projektisuunnitelma, toiminnallinen määrittely ja tekninen määrittely. Ongelmia projektin läpiviennissä voi tulla silloin, jos toimittaja ja asiakas eivät ymmärrä toisiaan. Tässä työssä tehdään SMSviestejä käsittelevä mobiilisovellus ja siihen liittyvät projektisuunnitelma sekä määrittelydokumentit. Mobiilisovellus ohjelmoidaan J2ME:llä, joka on sulautettujen järjestelmien ohjelmointiin suunniteltu Java-kieli. Sovellus tukee toisen asteen opiskelijoille suunnattuja mobiiliohjelmointi opintoja. Opintojakso kuuluu Pohjois- Karjalan ammattiopiston järjestämään turvallisuusalan koulutukseen. Sovelluksella voidaan lähettää ohjausviestejä OUMAN EH-60 -ohjaus- ja valvontayksikköön. Yksikön avulla voi ohjata ja valvoa esimerkiksi kiinteistön lämmönsäätöä, vesivahinkoja, oven lukitusta jne. Tässä työssä tehtävällä sovelluksella demonstroidaan kesämökin ohjausta. Langaton tiedonsiirto tulee tulevaisuudessa lisääntymään kiinteistöjen ohjaus- ja valvontajärjestelmänä. Hätä- ja valvontaviestit lähetetään automaattisesti kiinteistön omistajalle, hoivapalveluyrittäjälle, talohuoltoon tai hätäkeskukseen. Kiinteistön omistaja voi omalla matkapuhelimellaan ajasta ja paikasta riippumattavalvoa ja ohjata kiinteistöään reaaliaikaisesti. Pohjois-Karjalan ammattiopisto haluaa olla kehittämässä ja toteuttamassa turvallisuusalan koulutusta nyt ja tulevaisuudessa.

Business Intelligence -järjestelmä päätöksentekijöiden tukena asiantuntijayrityksessä

Työn tarkoituksena oli kartoittaa ja tehdä esiselvitys Business Intelligencen(BI) mahdollisuuksista tiedon hallinnassa. Tavoitteena oli selvittää, kuinka yritys voi tietotekniikan avulla paremmin hyödyntää operatiivisten järjestelmien tuottamia tietoja päätöksenteon tukena. Työssä sovellettiin konstruktiivista tutkimusotetta. Business Intelligence -teknologiaan tutustuttiin aluksi kirjallisuuden avulla. Ongelmaa lähestyttiin selvittämällä kohdeyrityksen tiedonhallinnan nykytila ja siihen liittyvät ongelmat. Käyttäjävaatimukset selvitettiin strukturoidulla kyselytutkimuksella. Lisäksi työn empiriaosuudessa tutustuttiin kahteen Business Intelligence -toteutukseen ja arvioitiin teknologian kypsyyttä suhteessa asiakasvaatimuksiin. Tiedonhallinnalta toivottiin joustavuutta ja helppokäyttöisyyttä.Erityisesti tutkimuksessa esiin nousi se, että tiedon jakeluun tarvitaan monipuolisempia vaihtoehtoja. Käyttäjät olivat valmiita hyödyntämään uusia BI-ominaisuuksia varsin laajalti. Haastavinta tutkimuksessa oli liiketoiminnan ymmärtäminen. Suurimmat BI-teknologian puutteet havaittiin loppukäyttäjän sovelluksissa. Tietovarastointiprosessiin liittyvä teknologia todettiin toimivaksi.

WiBed, A Platform for Commodity Wireless Testbeds

Testbeds are a stage between the simulation and the production stages. To this end they must be as close as possible to production environments (i.e. real hardware, on the field deployments) while also keeping the traits of experimentation facilities (i.e. fault tolerance, ease of deployment, testing and data collection). This paper presents WiBed, a FOSS platform for WiFi testbeds based on OpenWRT Linux made to run oncommodity IEEE802.11 WiFi routers part of the Community-lab.net project, a global testbed for Community networks. WiBedhas been designed to support realistic low layer network exper-iments (according to the OSI model). This work recolects thedetails of the architecture, design and implementation of WiBed consolidated during its operation as a testbed. In addition to a set of routing experimentation results obtained during the Wireless Battlemesh v7 where WiBed was used as testbed platform.

Python -ohjelmointiopas, versio 1

Python -ohjelmointiopas sisältää perustietoa ohjelmoinnista yleisesti sekä esittelee yksinkertaisia perusrakenteita, joiden pohjalta myös ohjelmoinnista mitään tietämätön ihminen voi luontevasti siirtyä ohjelmoinnin pariin. Opas on suunniteltu siten, että sen käyttäjän ei tarvitse osata etukäteen ohjelmoida, opas aloittaa käyttöympäristön asennuksesta, siihen tutustumisesta ja jatkaa siitä ohjelmointikeskeisimpiin aiheisiin.

Solution scanning as a key policy tool: identifying management interventions to help maintain and enhance regulating ecosystem services

The major task of policy makers and practitioners when confronted with a resource management problem is to decide on the potential solution(s) to adopt from a range of available options. However, this process is unlikely to be successful and cost effective without access to an independently verified and comprehensive available list of options. There is currently burgeoning interest in ecosystem services and quantitative assessments of their importance and value. Recognition of the value of ecosystem services to human well-being represents an increasingly important argument for protecting and restoring the natural environment, alongside the moral and ethical justifications for conservation. As well as understanding the benefits of ecosystem services, it is also important to synthesize the practical interventions that are capable of maintaining and/or enhancing these services. Apart from pest regulation, pollination, and global climate regulation, this type of exercise has attracted relatively little attention. Through a systematic consultation exercise, we identify a candidate list of 296 possible interventions across the main regulating services of air quality regulation, climate regulation, water flow regulation, erosion regulation, water purification and waste treatment, disease regulation, pest regulation, pollination and natural hazard regulation. The range of interventions differs greatly between habitats and services depending upon the ease of manipulation and the level of research intensity. Some interventions have the potential to deliver benefits across a range of regulating services, especially those that reduce soil loss and maintain forest cover. Synthesis and applications: Solution scanning is important for questioning existing knowledge and identifying the range of options available to researchers and practitioners, as well as serving as the necessary basis for assessing cost effectiveness and guiding implementation strategies. We recommend that it become a routine part of decision making in all environmental policy areas.