Passando da doutrina à prática: Ezequiel Corrêa dos Santos e a farmácia nacional

This article presents a sample of the activities of apothecary Ezequiel Corrêa dos Santos. He was notable not only for his professional career, but also for his political militancy, making an important contribution to the development of pharmaceutical sciences in Brazil, in the XIXth century.

Educação ambiental nas escolas da região de Ribeirão Preto (SP): concepções orientadoras da prática docente e reflexões sobre a formação inicial de professores de química

During short courses, 95 secondary school teachers from 49 state schools and 421 students from the Ribeirão Preto region (in Sao Paulo state, Brazil, with a population of 530,000) were asked to fill in different questionnaires. The points raised in the teacher's questionnaire were used as a guide to establish a continuous dialogue during the short courses. Most of the schools claimed to have some kind of environmental education (EE). Based on the questionnaires and dialogues we analyzed how the teachers' perceptions on EE reflect on the views secondary students hold about their own responsibility for preserving the environment. The role of universities in the preparation of chemistry teachers capable of effectively approaching EE is also discussed.

O espaço da prática de ensino e do estágio curricular nos cursos de formação de professores de química das ies públicas paulistas

The literature presents a new understanding of the teaching practice and the supervised internship.Mutual interaction between them is expected one providing subsidies to the other.The present article shows the conceptions prevailing at the São Paulo state universities regarding these activities.Students,when interviewed, report difficulties in dealing with classroom situations. It is possible to observe that chemists wish to prepare new chemists deviating from the objectives of a Chemistry course leading to teaching credentials .

A prática docente na formação do pós-graduando em química

The present work describes how a group of chemistry graduate students have improved their teaching skills by teaching extension courses. It is suggested that future teachers have much to be gained by sharing the insights they have whilst teaching with their peers and students. This work explores the implications in teaching and learning and the relationship between teachers and students. This relationship requires mutual respect of ideas as well as continuous critical evaluation in both directions.

Recursos humanos para novos cenários

The Brazilian Chemical Society - SBQ has made substantial contributions to the formation of qualified human resources at all levels since its foundation in 1977. Several papers addressing this subject have been published in Quimica Nova by different authors over the last years. In this paper, we discuss the present need for "Curriculum Guidelines" for undergraduate education in Chemistry with actions to be taken in accord with the Principles of Green Chemistry and Sustainability.

Sistemas tampão: uma estrutura didática teórico-prática

Courses with practical and theoretical classes are potentially didactic structures for the development of motor and complex cognitive skills when operated in an integrated manner. When worked aligned, theory and practice enable a clearer view of the issue, opening scope for introducing concepts from other disciplines and for the development of lab skills. This paper presents a methodology for biochemistry labwork that promotes the teaching of the buffering systems contents together with to the development of scientific research practice concepts in an interdisciplinary perspective that integrates theory and practice.

Preparação e caracterização espectroscópica de complexos de boro: uma proposta para uma prática integrada de química inorgânica

As a proposal for an undergraduate second or third year inorganic laboratory course, the present paper describes the preparation of three representative boron complexes: potassium tetrafluoroborate, pyridoxin boron complex and potassium bis(oxalato)borate. The complexes are characterised by infrared and multinuclear magnetic resonance spectroscopy (¹H, 11B and 19F) where isotopic effects are demonstrated.

Biomassa em aula prática de Química Orgânica Verde: cravo-da-índia como fonte simultânea de óleo essencial e de furfural

This work presents an optimized integrated experiment for isolation of clove bud essential oil, rich in eugenol, and subsequent utilization of the solid residue for furfural synthesis. The operationally simple laboratory protocols and utilization of water as a solvent in both operations, plus the use of biomass as the starting material for preparation of versatile intermediates in organic synthesis, make the experiments attractive for undergraduate experimental organic chemistry courses in the context of green chemistry. In addition, this is the first description of the use of biomass (clove bud) in the simultaneous preparation of two chemical feedstocks, eugenol and furfural, on experimental organic chemistry courses.

Síntese da fenitoína assistida por micro-ondas: proposta de aula prática para alunos de graduação

Microwave synthesis is considered a breakthrough in the field of chemistry due to its benefits over conventional heating methods. We describe, for the first time, the total synthesis of phenytoin adapted for a microwave reactor, proposed as an experiment for undergraduate courses. When carried out with microwaves, the synthetic route provided phenytoin in 6 min and 30 s, while for conventional heating the total time was 170 min. The experiment also involves rapid identification of compounds by TLC, ¹H NMR, FT-IR and melting points determination.

Estudo das relações entre estrutura e atividade de parabenos: uma aula prática

Parabens are p-hydroxybenzoic acid esters widely used as preservatives. With the aim of teaching the structure-activity relationships (SAR) knowledge in a practical form, this paper proposed a practical class to view the SAR of parabens as antimicrobial agents. Methyl, ethyl, n-propyl, isopropyl and isopentyl paraben compounds were synthesized and their respective antimicrobial activities were assessed through determination of minimum inhibitory concentrations (MIC) against Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922 stains. With the MIC values, it was possible to verify theircorrelation with calculated lipophilicity (ClogP). This method can be applied in practical Medicinal Chemistry classes.

Cromatografia gasosa-espectrometria de massas e derivatização assistida por micro-ondas na identificação de isômeros de glicose: uma prática para o ensino avançado em análise e caracterização de compostos orgânicos

This work reports a practical case based on the use of microwave-assisted derivatization and GC-MS for the analysis of glucose. Using two different methods for derivatization, one reference compound and the calculated dipole moment, all the isomers of glucose were identified. Identification was corroborated for the assignment of structures using the mass spectra. With this work, students are expected to associate different types of information to solve the complex problem of the analysis of glucose.

A FORMAÇÃO DE PROFESSORES EM COMUNIDADES DE PRÁTICA: O CASO DE UM GRUPO DE PROFESSORES DE QUÍMICA EM FORMAÇÃO INICIAL

This work deals with communities of practice and their contribution to pre-service teacher training. A group of eight pre-service chemistry teachers was accompanied during their participation in the PIBID program. Based on their interaction in planning teaching activities, the group was characterized as a community of practice. For this characterization the three dimensions of communities of practice were observed: mutual engagement, joint enterprise and shared repertoire. The results showed that the community of practice was essential for the training of pre-service chemistry teachers. Through community practice, pre-service teachers were able to learn more about their future practice as chemistry teachers.

INTERAÇÕES FÁRMACO-RECEPTOR: APLICAÇÕES DE TÉCNICAS COMPUTACIONAIS EM AULA PRÁTICA SOBRE A EVOLUÇÃO DOS INIBIDORES DA ENZIMA CONVERSORA DE ANGIOTENSINA

Teaching classes and events regarding the molecular aspects of drug-receptor interactions is not an easy task. The ligand stereochemistry and the spatial arrangement of the macromolecular targets highly increase the complexity of the process. In this context, the use of alternative and more playful approaches could allow students to gain a more thorough understanding of this important topic in medicinal chemistry. Herein, we describe a practical teaching approach that uses computational strategies as a tool for drug-receptor interaction studies performed for angiotencsin converting enzyme inhibitors (ACEi). Firstly, the students learn how to find the crystallographic structure (enzyme-ligand complex). Then, they proceed to the treatment of crude crystallographic data. Thereafter, they learn how to analyze the positioning of the drug on the active site of the enzyme, looking for regions related to the molecular recognition. At the end of the study, students can summarize the molecular requirements for the interaction and the structure-activity relationships of the studied drugs.

A especificidade do estético e a razão prática em Schiller

O presente trabalho examina um problema recorrente no pensamento de Friedrich Schiller: o da unidade da razão na autonomia das formas fundamentais da racionalidade. Ele é analisado aqui no contexto da correspondência de Schiller com o Príncipe de Augustenburg em 1793 e do ensaio "Sobre a utilidade moral dos costumes estéticos". O propósito do trabalho é discutir esse problema desde a perspectiva do nexo entre a esfera estética e a razão prática. Segundo Schiller, o gosto seria uma condição necessária da liberdade.