NUTRITION AND HEALTH STATUS OF HIV-INFECTED ADULTS ON ARVS AT AMREF CLINIC KIBERA URBAN SLUM, KENYA

The health of people living with HIV and AIDS (PLWHA) is nutritionally challenged in many nations of the world. The scourge has reduced socio-economic progress globally and more so in sub-Saharan Africa (SSA) where its impact has been compounded by poverty and food insecurity. Good nutrition with proper drug use improves the quality of life for those infected but it is not known how PLWHA exposed to chronic malnutrition and food shortages from developing nations adjust their nutrition with use of Anti-Retro-viral Drugs (ARVs). This study assessed nutritional status, dietary practices, and dietary management of common illnesses that hinder daily food intake by the patients and use of ARVs with food recommendations provided by the health care givers. A descriptive case study design was used to sample 120 HIV-infected patients using systematic sampling procedure. These patients sought health care from an urban slum, Kibera AMREF clinic. Data were collected by anthropometric measurements, bio-chemical analysis, semi-structured questionnaire and secondary data. The Statistical Package for Social Sciences (SPSS) and the Nutri-Survey software packages were used to analyze data. Dietary intakes of micro-nutrients were inadequate for >70% of the patients when compared to the Recommended Daily Requirements. When Body Mass Indices (BMI) were used, only 6.7% of the respondents were underweight (BMI<18.5kg/m2) and 9.2% were overweight (BMI> 25kg/m2), serum albumin test results (mean 3.34±0.06g/dl) showed 60.8% of the respondents were protein deficient and this was confirmed by low dietary protein intakes. The BMI was not related to dietary nutrient intakes, serum albumin and CD4 cell counts (p>0.05). It appeared that there was no significant difference in BMI readings at different categories of CD4 cell count (p>0.05) suggesting that the level of immunity did not affect weight gain with ARV as observed in many studies from developed countries. Malnutrition was, therefore, evident among the 60.8% of the cases as identified by serum albumin tests and food intake was not adequate (68%) for the patients as they ate once a day due to lack of food. National food and nutrition policy should incorporate food security boosting guidelines for the poor people infected with HIV and using ARVs.

Detection of all four dengue serotypes in Aedes aegypti female mosquitoes collected in a rural area in Colombia

The Aedes aegypti vector for dengue virus (DENV) has been reported in urban and periurban areas. The information about DENV circulation in mosquitoes in Colombian rural areas is limited, so we aimed to evaluate the presence of DENV in Ae. aegypti females caught in rural locations of two Colombian municipalities, Anapoima and La Mesa. Mosquitoes from 497 rural households in 44 different rural settlements were collected. Pools of about 20 Ae. aegypti females were processed for DENV serotype detection. DENV in mosquitoes was detected in 74% of the analysed settlements with a pool positivity rate of 62%. The estimated individual mosquito infection rate was 4.12% and the minimum infection rate was 33.3/1,000 mosquitoes. All four serotypes were detected; the most frequent being DENV-2 (50%) and DENV-1 (35%). Two-three serotypes were detected simultaneously in separate pools. This is the first report on the co-occurrence of natural DENV infection of mosquitoes in Colombian rural areas. The findings are important for understanding dengue transmission and planning control strategies. A potential latent virus reservoir in rural areas could spill over to urban areas during population movements. Detecting DENV in wild-caught adult mosquitoes should be included in the development of dengue epidemic forecasting models.

Turismo em Espaço Rural

O turismo é uma das principais atividades geradoras de emprego e riqueza em todo o mundo, Portugal não é exceção à regra, este setor de atividade é o que mais contribui para a revitalização do espaço rural, consistindo em oportunidades de empreendedorismo, numa vertente de recuperação de espaços que tradicionalmente eram agrícolas, numa ótica de novo negócio, para um segmento de mercado específico. O Turismo em Espaço Rural em Portugal surge no final da década de 70 do século passado, consistindo no aproveitamento e na adaptação de património construído para fins de alojamento em zonas rurais envolvendo, principalmente, casas rústicas, quintas com atividades agrícolas e hotéis rurais. Na sua essência o Turismo em Espaço Rural satisfaz as necessidades de um grupo crescente de consumidores citadinos que procura romper com o quotidiano e obter uma experiência revigorante, através da procura do "autêntico", a nostalgia pelo passado, em perfeita integração com a natureza, atividades ao ar livre em contextos naturais, relaxamento num ambiente calmo e tranquilo, atributos que não encontram no meio urbano ao mesmo tempo que constituem um fator de valorização do meio rural e de reequilíbrio económico-social.

O impacto da urbanização na violência : Contraste urbano e rural

A urbanização mais recente em Portugal caracterizou-se por uma bipolarização concentrada em Lisboa e no Porto acompanhada também pelo crescimento de população ao longo do litoral norte e por fim pelo crescimento de algumas cidades mais pequenas. A construção de habitações sociais para albergar famílias mais carenciadas e com dificuldades económicas veio acompanhada também, ao longo do tempo, por um crescimento da violência urbana. Contudo, pode-se constatar que a criminalidade violenta e grave tem diminuído, pelo menos desde 2010. Este estudo tem o objetivo de descrever as diferenças existentes na criminalidade entre uma área predominantemente urbana e outra área predominantemente rural entre 2010 e 2015 com a finalidade de perceber o que existe nas áreas urbanas que não existe nas áreas rurais, para poder estabelecer uma relação com a criminalidade violenta e grave em ambientes urbanos. Para tal, foi calculada a taxa de criminalidade violenta e grave da área do Subdestacamento Territorial de Alcabideche e do Posto Territorial de Merceana, para perceber a incidência criminal deste fenómeno no período de estudo. Foram também conduzidos inquéritos por entrevista a comandantes e militares responsáveis pela investigação criminal em ambos os locais que exerceram funções entre 2010 e 2015. Chegou-se à conclusão que a criminalidade violenta e grave é bastante mais significativa nas áreas urbanas e a principal causa e fonte da maior parte desta criminalidade poderão ser os bairros de habitação social, no caso de Alcabideche, que albergam algumas pessoas de famílias desestruturadas, onde se concentram muitos indivíduos num mesmo local que poderão praticar crimes, nomeadamente, a crimes violentos e graves.

Demanda de las cocinas de inducción aplicado a la parroquia rural El Valle, cantón Cuenca, análisis comparativo 2014-2015

La presente investigación tiene como objetivo realizar un estudio piloto de la demanda de cocinas de inducción del año 2014-2015 y posteriormente un análisis comparativo. Este estudio es aplicado a la parroquia El Valle, perteneciente al cantón Cuenca, excluyendo el área urbana, empleando como objeto de estudio a los jefes de hogar de la parroquia, a través de dos modelos Logit binario con iguales características para realizar la comparación de ambos años. Los principales resultados en el año 2014 muestran que, en relación al tamaño de la muestra en la parroquia rural El Valle, el 33% de la población están dispuestos a adquirir la cocina de inducción, los factores que influyen en la decisión de adquirir la cocina de inducción son: el ingreso obteniendo un efecto positivo y el costo con un efecto negativo. En la estimación del costo se obtiene que, considerando que todos los hogares encuestados de la parroquia rural El Valle adquirirán la cocina de inducción, los costos totales por hogar en promedio es de $573.34. Mientras los resultados del año 2015 son, que el 20% de la población encuestada en la parroquia adquirirán la cocina de inducción, las variables edad y pago de factura eléctrica son las que tienen mayor influencia en el modelo, existiendo una relación inversa en ambas y en la determinación del costo se obtiene que es de $526.70 aproximadamente.

Urban Agriculture Oriented towards Self-Supply, Social and Commercial Purpose: A Typology

Urban agriculture, a dynamic multifunctional phenomenon, affects the spatial diversification of urban land use, its valorization and its governance. Literature acknowledges its contribution to the development of sustainable cities. The dimension and extent of this contribution depends significantly on the particular form and function of urban agriculture. However, the complexity of interests and dimensions is insufficiently covered by theory. This paper proposes a typology for urban agriculture, supporting both theory building and practical decision processes. We reviewed and mapped the diversity of the types of agriculture found along three beneficial dimensions (self-supply, socio-cultural, commercial) for product distribution scale and actors. We distinguish between ideal types, subtypes and mixed types. Our intention is to include a dynamic perspective in the typology of urban agricultural land use because transition processes between types are observable due to the existence of complex motivations and influences. In a pilot study of 52 urban agriculture initiatives in Germany, we tested the validity of the typology and discussed it with stakeholders, proving novelty and relevance for profiling discussions.

Colonoscopy Access and Utilization – Rural Disparities in the Carolinas, 2001- 2010

The objective of this study was to identify disparities in colonoscopy utilization and access to care across urban-rural populations in the Carolinas. NC and SC are in the top 10% of states for the proportion of residents living in rural areas, making these states an ideal location to examine the effects of access to care. This report illustrates key findings from a study using ambulatory surgery discharge data from NC and SC from 2001-2010. Described is the geographic distribution of colonoscopy providers in the Carolinas, estimated colonoscopy utilization in urban and rural populations, and how patients seek their care based on the availability of providers in their county.

Vulnerable Rural Counties: The Changing Rural Landscape, 2000–2010

Understanding the demography of rural America is vital to understanding what programs, interventions and policy initiatives are needed to improve health care access, delivery and outcomes. Overall findings suggest that rural America experienced the recession that ended the 2000–2010 decade more severely than did urban America. Loss of income, declining population and reduced health care resources marked the period for most rural counties. Rural counties will need continued monitoring in the present decade to ascertain whether these adverse trends continue and to identify any policy approaches that can serve to ameliorate losses in health care services.

Contribución de la misión de naciones unidas en Guatemala – Minugua, a la promoción, defensa y garantía de los derechos de la población indígena guatemalteca (1994 a 2004)

El conflicto armado en Guatemala se originó por el abuso de poder, la desigualdad, la exclusión y la profunda discriminación, sobre todo hacia la población indígena, a la que se le han desconocido históricamente sus derechos y que fue la más afligida durante el conflicto. Lo que desembocó en el nacimiento de grupos al margen de la ley, cuyo propósito fue reivindicar los derechos de la población, así como la equidad y justicia social. El conflicto se caracterizó por la formación de grupos paramilitares, la violación al Derecho Internacional Humanitario, el elevado número de víctimas del conflicto, mayoritariamente indígenas y porque más del 85% de las violaciones a los derechos humanos fueron perpetradas por el Estado. Gracias a la voluntad política, al respaldo de la comunidad internacional, especialmente de la Organización de Naciones Unidas -ONU, y a los buenos oficios de la Comisión Nacional de Reconciliación – CNR, se lograron firmar los Acuerdos de Paz y dar fin a este cruento conflicto de más de 36 años. Las partes firmantes vieron la necesidad de que un ente autónomo e imparcial de Naciones Unidas, verificara el cumplimiento de La Misión de Naciones Unidas en Guatemala - MINUGUA contribuyó a la promoción, defensa y garantía de los derechos de la población indígena guatemalteca. Específicamente, incidió en el cumplimiento de los compromisos contenidos en el Acuerdo sobre Identidad y Derechos de los Pueblos Indígenas guatemaltecos –AIDPI, que fue suscrito el 31 de marzo de 1995, asimismo, contribuyó a la garantía del derecho a la justicia de la población indígena, lo que se evidenció en las acciones y el papel que desempeñó en los componentes de verdad, justicia y reparación.

Desenvolvimento do potencial em crianças em idade pré-escolar em meio urbano/meio rural: Um estudo exploratório nos Concelhos de Évora e Viana do Alentejo

A educação pré-escolar assume um papel fundamental no desenvolvimento das crianças que se quer cada vez mais abrangente e transversal. O nosso estudo tem como objectivo compreender se o desenvolvimento do potencial das crianças em idade pré-escolar está associado à frequência de actividades extracurriculares e ao meio onde residem. Realizou-se com uma amostra de 46 crianças, em dois Jardins de Infância, um de meio urbano e outro rural, nos concelhos de Évora e Viana do Alentejo. Utilizámos os instrumentos de avaliação do Modelo de Spectrum (Krechevsky 2001). A análise de resultados demonstrou que a população urbana apresentou um desenvolvimento do potencial superior à população rural em quase todas as actividades. A concluir destacamos as implicações deste estudo para a educação pré-escolar, nomeadamente no que se refere à sua organização e avaliação. ABSTRACT: The pre-school education plays a key role in the development of children needing to be more comprehensive and cross. Our study aims to understand if the potential development of children in preschool is associated with the frequency of extracurricular activities and the environment in which they reside. Conducted with a sample of 46 children in two kindergartens, one urban and another one rural, in the districts of Évora, Viana do Alentejo. We used the assessment tools of the Spectrum Model (Krechevsky 2001). The analysis results showed that the urban population had a higher potential development of the rural population in almost all activities. Finally, we highlight the implications of this study for pre-school education, particularly as regards their organization and evaluation.

Unlocking the Potential of Women in the Rural Development Process of Republic of Srpska: The Role of Extension Service

In Bosnia Herzegovina the development of clear policy objectives and endorsement of a long-term, coherent and mutual agricultural and rural development policy have also been affected by structural problems: a lack of reliable information on population and other relevant issues, the absence of an adequate land registry system and cadastre. Moreover in BiH the agricultural and rural sectors are characterized by many factors that have typically affected transition countries such as land fragmentation, lack of agricultural mechanization and outdated production technologies, and rural aging, high unemployment and out-migration. In such a framework the condition and role of women in rural areas suffered for the lack of gender disaggregated data and a consequent poor information that lead to the exclusion of gender related questions in the agenda of public institutions and to the absence of targeted policy interventions. The aim of the research is to investigate the role and condition of women in the rural development process of Republic of Srpska and to analyze the capacity of extension services to stimulate their empowerment. Specific research questions include the status of women in the rural areas of Republic of Srpska, the role of government in fostering the empowerment of rural women, and the role of the extension service in supporting rural women. The methodology - inspired by the case study method developed by R. Yin - is designed along the three specific research questions that are used as building blocks. Each of the three research questions is investigated with a combination of methodological tools - including surveys, experts interviews and focus groups - aimed to overcome the lack of data and knowledge that characterize the research objectives.

Analysis of heat-related phenomena and their interactions at different spatio-temporal scales

This thesis analyzes the impact of heat extremes in urban and rural environments, considering processes related to severely high temperatures and unusual dryness. The first part deals with the influence of large-scale heatwave events on the local-scale urban heat island (UHI) effect. The temperatures recorded over a 20-year summer period by meteorological stations in 37 European cities are examined to evaluate the variations of UHI during heatwaves with respect to non-heatwave days. A statistical analysis reveals a negligible impact of large-scale extreme temperatures on the local daytime urban climate, while a notable exacerbation of UHI effect at night. A comparison with the UrbClim model outputs confirms the UHI strengthening during heatwave episodes, with an intensity independent of the climate zone. The investigation of the relationship between large-scale temperature anomalies and UHI highlights a smooth and continuous dependence, but with a strong variability. The lack of a threshold behavior in this relationship suggests that large-scale temperature variability can affect the local-scale UHI even in different conditions than during extreme events. The second part examines the transition from meteorological to agricultural drought, being the first stage of the drought propagation process. A multi-year reanalysis dataset involving numerous drought events over the Iberian Peninsula is considered. The behavior of different non-parametric standardized drought indices in drought detection is evaluated. A statistical approach based on run theory is employed, analyzing the main characteristics of drought propagation. The propagation from meteorological to agricultural drought events is found to develop in about 1-2 months. The duration of agricultural drought appears shorter than that of meteorological drought, but the onset is delayed. The propagation probability increases with the severity of the originating meteorological drought. A new combined agricultural drought index is developed to be a useful tool for balancing the characteristics of other adopted indices.

Nature-based solutions for urban heat island effect mitigation: the case study of Isla, Malta

Global population growth reflects how humans increasingly exploited Earth's resources. Urbanization develops along with anthropization. It is estimated that nearly 60% of the world's population lives in urban areas, which symbolize the denaturalized dimension of current modernity. Cities are artificial ecosystems that suffer most from environmental issues and climate change. The Urban Heat Island (UHI) effect is a common microclimatic phenomenon affecting cities, which causes considerable differences between urban and rural areas temperatures. Among the driving factors, the lack of vegetation in urban settlements can damage both humans and the environment (health diseases, heat waves caused deaths, biodiversity loss, and so on). As the world continues to urbanize, sustainable development increasingly depends on successful management of urban areas. To enhance cities’ resilience, Nature-based Solutions (NbSs), are defined as an umbrella concept that encompasses a wide range of ecosystem-based approaches and actions to climate change adaptation (CCA) and disaster risk reduction (DRR). This paper analyzes a 15-days study on air temperature trends carried out in Isla, a small locality in the Maltese archipelago, and proposes Nature-based Solutions-characterized scenarios to mitigate the Urban Heat Island effect the Mediterranean city is affected by. The results demonstrates how in some areas where vegetation is present, lower temperatures are recorded than in areas where vegetation is absent or scarce. It also appeared that in one location, the specific type of vegetation does not contribute to high temperature mitigation, whereas in another one, different environmental parameters can influence the measurements. Among the case-specific Nature-based Solutions proposed there are vertical greening (green wall, façades, ground based greening, etc.), tree lines, green canopy, and green roofs.

The Cratylia Mollis Seed Lectin Induces Membrane Permeability Transition In Isolated Rat Liver Mitochondria And A Cyclosporine A-insensitive Permeability Transition In Trypanosoma Cruzi Mitochondria.

Previous results provided evidence that Cratylia mollis seed lectin (Cramoll 1,4) promotes Trypanosoma cruzi epimastigotes death by necrosis via a mechanism involving plasma membrane permeabilization to Ca(2+) and mitochondrial dysfunction due to matrix Ca(2+) overload. In order to investigate the mechanism of Ca(2+) -induced mitochondrial impairment, experiments were performed analyzing the effects of this lectin on T. cruzi mitochondrial fraction and in isolated rat liver mitochondria (RLM), as a control. Confocal microscopy of T. cruzi whole cell revealed that Cramoll 1,4 binding to the plasma membrane glycoconjugates is followed by its internalization and binding to the mitochondrion. Electrical membrane potential (∆Ψm ) of T. cruzi mitochondrial fraction suspended in a reaction medium containing 10 μM Ca(2+) was significantly decreased by 50 μg/ml Cramoll 1,4 via a mechanism insensitive to cyclosporine A (CsA, membrane permeability transition (MPT) inhibitor), but sensitive to catalase or 125 mM glucose. In RLM suspended in a medium containing 10 μM Ca(2+) this lectin, at 50 μg/ml, induced increase in the rate of hydrogen peroxide release, mitochondrial swelling, and ∆Ψm disruption. All these mitochondrial alterations were sensitive to CsA, catalase, and EGTA. These results indicate that Cramoll 1, 4 leads to inner mitochondrial membrane permeabilization through Ca(2+) dependent mechanisms in both mitochondria. The sensitivity to CsA in RLM characterizes this lectin as a MPT inducer and the lack of CsA effect identifies a CsA-insensitive MPT in T. cruzi mitochondria.

Nanomolar Levels Of Pahs In Extracts From Urban Air Induce Mapk Signaling In Hepg2 Cells.

Polycyclic aromatic hydrocarbons (PAHs) are common environmental pollutants that occur naturally in complex mixtures. Many of the adverse health effects of PAHs including cancer are linked to the activation of intracellular stress response signaling. This study has investigated intracellular MAPK signaling in response to PAHs in extracts from urban air collected in Stockholm, Sweden and Limeira, Brazil, in comparison to BP in HepG2 cells. Nanomolar concentrations of PAHs in the extracts induced activation of MEK4 signaling with down-stream increased gene expression of several important stress response mediators. Involvement of the MEK4/JNK pathway was confirmed using siRNA and an inhibitor of JNK signaling resulting in significantly reduced MAPK signaling transactivated by the AP-1 transcription factors ATF2 and c-Jun. ATF2 was also identified as a sensitive stress responsive protein with activation observed at extract concentrations equivalent to 0.1 nM BP. We show that exposure to low levels of environmental PAH mixtures more strongly activates these signaling pathways compared to BP alone suggesting effects due to interactions. Taken together, this is the first study showing the involvement of MEK4/JNK/AP-1 pathway in regulating the intracellular stress response after exposure to nanomolar levels of PAHs in environmental mixtures.