Molecularly designed layer-by-layer (LbL) films to detect catechol using information visualization methods

The control of molecular architectures has been exploited in layer-by-layer (LbL) films deposited on Au interdigitated electrodes, thus forming an electronic tongue (e-tongue) system that reached an unprecedented high sensitivity (down to 10-12 M) in detecting catechol. Such high sensitivity was made possible upon using units containing the enzyme tyrosinase, which interacted specifically with catechol, and by processing impedance spectroscopy data with information visualization methods. These latter methods, including the parallel coordinates technique, were also useful for identifying the major contributors to the high distinguishing ability toward catechol. Among several film architectures tested, the most efficient had a tyrosinase layer deposited atop LbL films of alternating layers of dioctadecyldimethylammonium bromide (DODAB) and 1,2-dipalmitoyl-sn-3-glycero-fosfo-rac-(1-glycerol) (DPPG), viz., (DODAB/DPPG)5/DODAB/Tyr. The latter represents a more suitable medium for immobilizing tyrosinase when compared to conventional polyelectrolytes. Furthermore, the distinction was more effective at low frequencies where double-layer effects on the film/liquid sample dominate the electrical response. Because the optimization of film architectures based on information visualization is completely generic, the approach presented here may be extended to designing architectures for other types of applications in addition to sensing and biosensing. © 2013 American Chemical Society.

Análise e modelação de perdas em conversores CC-CC do tipo Boost entrelaçados

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Integral transform solution for the forced convection of herschel-bulkley fluids in circular tubes and parallel-plates ducts

ABSTRACT: The thermal entry region in laminar forced convection of Herschel-Bulkley fluids is solved analytically through the integral transform technique, for both circular and parallel-plates ducts, which are maintained at a prescribed wall temperature or at a prescribed wall heat flux. The local Nusselt numbers are obtained with high accuracy in both developing and fully-developed thermal regions, and critical comparisons with previously reported numerical results are performed.

Comparing label free electrochemical impedimetric and capacitive biosensing architectures

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Stress analysis in oral obturator prostheses over parallel and tilted implants: photoelastic imaging

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Reformulation and a Lagrangian heuristic for lot sizing problem on parallel machines

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A Reference Architecture based on Reflection for Self-adaptive Software

Self-adaptive Software (SaS) presents specific characteristics compared to traditional ones, as it makes possible adaptations to be incorporated at runtime. These adaptations, when manually performed, normally become an onerous, error-prone activity. In this scenario, automated approaches have been proposed to support such adaptations; however, the development of SaS is not a trivial task. In parallel, reference architectures are reusable artifacts that aggregate the knowledge of architectures of software systems in specific domains. They have facilitated the development, standardization, and evolution of systems of those domains. In spite of their relevance, in the SaS domain, reference architectures that could support a more systematic development of SaS are not found yet. Considering this context, the main contribution of this paper is to present a reference architecture based on reflection for SaS, named RA4SaS (Reference Architecture for SaS). Its main purpose is to support the development of SaS that presents adaptations at runtime. To show the viability of this reference architecture, a case study is presented. As result, it has been observed that RA4SaS has presented good perspective to efficiently contribute to the area of SaS.

On the distinct molecular architectures of dipping- and spray-LbL films containing lipid vesicles

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Metabolic profiling by ultra-performance liquid chromatography-mass spectrometry and parallel factor analysis for the determination of disease biomarkers in Eucalyptus

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

An Efficient Parallel Algorithm for Multiple Sequence Similarities Calculation Using a Low Complexity Method

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Improvements in the score matrix calculation method using parallel score estimating algorithm

The increasing amount of sequences stored in genomic databases has become unfeasible to the sequential analysis. Then, the parallel computing brought its power to the Bioinformatics through parallel algorithms to align and analyze the sequences, providing improvements mainly in the running time of these algorithms. In many situations, the parallel strategy contributes to reducing the computational complexity of the big problems. This work shows some results obtained by an implementation of a parallel score estimating technique for the score matrix calculation stage, which is the first stage of a progressive multiple sequence alignment. The performance and quality of the parallel score estimating are compared with the results of a dynamic programming approach also implemented in parallel. This comparison shows a significant reduction of running time. Moreover, the quality of the final alignment, using the new strategy, is analyzed and compared with the quality of the approach with dynamic programming.

Bit-parallel coprocessor for standard ECC-GF(2m) on FPGA

This paper presents the design of a high-speed coprocessor for Elliptic Curve Cryptography over binary Galois Field (ECC- GF(2m)). The purpose of our coprocessor is to accelerate the scalar multiplication performed over elliptic curve points represented by affine coordinates in polynomial basis. Our method consists of using elliptic curve parameters over GF(2163) in accordance with international security requirements to implement a bit-parallel coprocessor on field-programmable gate-array (FPGA). Our coprocessor performs modular inversion by using a process based on the Stein's algorithm. Results are presented and compared to results of other related works. We conclude that our coprocessor is suitable for comparing with any other ECC-hardware proposal, since its speed is comparable to projective coordinate designs.

Using Threads to Overcome Synchronization Delays in Parallel Multiple Progressive Alignment Algorithms

Sao Paulo State Research Foundation-FAPESP

Seasonal variation of biotic and abiotic parameters in parallel neotropical fishponds

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Recovery Tests of an Hybrid Current Limiter Composed of a SFCL in Parallel to an Air-Core Power Reactor

The resistive-type superconducting fault current limiters (RSFCL) prototypes using YBCO-coated conductors have shown current limitation for medium voltage class applications for acting time up to 80 ms. By connecting an air-core reactor in parallel with the RSFCL, thus making an hybrid current limiter, one can extend the acting time for up to 1 s. In this work, we report the performance of a hybrid current limiter subjected to an AC peak fault current of 2 kA during 1 s for which within the first 80 ms the SFCL limits the current concurrently with the air-core reactor, and for the remaining 920 ms, only the air-core reactor limits the current. In order to evaluate the actual conditions for subsequent reconnection of RSFCL to the power grid, the hybrid fault current limiter was tested varying the time interval for recovery from 900 ms and 1.2 s, followed again by the concurrent operation of the hybrid limiter during 1 s (SFCL during 80 ms). From this evaluation test, the recovery time can be measured and compared using the voltage peak generated in superconducting module from the first and second fault test. The recovery time was also determined through the pulsed current method (PCM) on short-length sample test. The results showed that the fault current was limited from 1.9 kA down to 514 A after 1 cycle of 60 Hz frequency, with recovery time lower than 1.2 s for two subsequent fault current tests.