999 resultados para mortalidade embrionária
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Pós-graduação em Medicina Veterinária - FMVZ
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Pós-graduação em Ciências Biológicas (Zoologia) - IBB
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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O objetivo foi descrever a mortalidade entre idosos em Araraquara (SP), no período de 2006 a 2011. Estudo epidemiológico descritivo, tendo como fontes de dados o Sistema de Informações sobre Mortalidade e a Fundação Sistema Estadual de Análise de Dados. Foi calculada razão entre coeficientes de mortalidade por ponto (R) e por intervalo de 95% de confiança (IC95%). Observou-se mais de 60% dos idosos com nível baixo de escolaridade, sendo que 76% faleceram em hospitais. Entre 2006 e 2008, as diferenças foram estatisticamente significantes entre homens e mulheres, predominando as doenças circulatórias com R = 1,41 (IC95%:1,24-1,58), respiratórias com R = 1,49 (IC95%:1,22-1,76) e neoplasias com R = 1,79 (IC95%: 1,40-2,18). Entre 2009 e 2011, obteve-se, para as causas circulatórias R = 1,18 (IC95%:1,03-1,33), sendo significativas as diferenças para as respiratórias com R = 1,33 (IC95%:1,11-1,55) e câncer sendo R = 1,94 (IC95%:1,53-2,35). O diabetes mellitus e as causas externas apareceram, respectivamente, como quarta e quinta causas de mortes mais frequentes na população idosa. O padrão de mortalidade encontrado ressalta a importância de ações voltadas à redução das principais causas de morte, como o incremento da cobertura da vacina contra a influenza e o controle da hipertensão arterial e do diabetes mellitus.
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Pós-graduação em Fisiopatologia em Clínica Médica - FMB
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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OBJECTIVE: to describe elderly mortality from cardiovascular and respiratory diseases and neoplasms in Marilia (SP). METHODS: this is a descriptive study of mortality from three diseases as defined by the 10th International Classification of Diseases, between 1998-2000 and 2005-2007. Mortality Information System records were used. Mortality rates by age and sex were calculated. RESULTS: circulatory diseases were the main causes of death among the elderly (39.25%). Neoplasm decline was noticed in both sexes and in those aged 60-69, particularly prostate cancer in men (-83.86%) and breast cancer (-70.96%) in this age group. Deaths from respiratory diseases increased in patients aged 80 and older: 39.31% in men and 57.92% in women. CONCLUSION: mortality from circulatory diseases and neoplasms among the elderly showed a decline, with increased mortality from respiratory system problems in patients 80 years of age and older.
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Infertility is directly related to chromosomal abnormalities in germ cells. Among them, the aneuploidies are the most frequent chromosomal abnormalities and responsible for embryo implantation failures, miscarriages, fetal losses and newborns with congenital malformations, mental disability and neuropsychomotor developmental delay. Male patients with normal somatic karyotype may present different rates of aneuploidies in sperm, resulting in abnormal embryos. This study aimed to correlate the frequency of chromosomal aneuploidies in spermatozoa with embryo implantation rate in couples undergoing assisted reproductive techniques. The methodology has included chromosomal analysis by GTG banding and molecular cytogenetic study using Fluorescent In Situ Hybridization technique for evaluation of chromosomes 9, X and Y in germ cells of 22 patients referred to the Human Reproduction Service of the Clinical Hospital FMRP-USP. Embryo implantation rates were determined by hormonal evaluation in maternal peripheral blood and ultrasound confirmation. Two patients presented abnormal karyotype, characterized by polymorphism of the heterochromatic region of the long arm of chromosome 9 and a satellite in the short arm of chromosome 22. Both alterations, usually considered variants of normality, have been related to infertility phenotype and miscarriages. Significant differences were detected between couples who presented pregnancy (group 1) and couples with embryo implantation failure (group 2), with higher frequency of aneusomy and diploidy of chromosome 9, as well as total aneuploidy in sperm of group 2 patients. Our results suggest a correlation between aneuploidy and embryo implantation rates, since the infertile group with reproductive failure has showed higher frequency of aneuploidy. Screening for aneuploidies detection in male germ cells should be included in order to decrease embryo implantation failures, miscarriages and fetuses with chromosomal ...
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The success in implementing an embryo transfer program derives from many factors. The embryo recovery rate is one of the most important factors, and allows the transfer to the recipient mare. This rate comes from a group of elements such as donor´s characteristics, collection date, reproductive management, semen quality, technician skill. Mainly because of the great importance of this direct interference on the results of an embryo recovery program, this study aimed to review the factors involved in embryo recovery rates in donor mares during an embryo transfer, suggesting some ways of improving these results
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Pós-graduação em Fisiopatologia em Clínica Médica - FMB
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Pós-graduação em Fisiopatologia em Clínica Médica - FMB
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Mouse embryo production by superstimulation is a multifactorial process. To minimize the number of sacrificed animals and to maximize the results of the superstimulatory treatment, it should be possible to predict the risk of do not get embryos from such a treated animal. This work aimed to evaluate if the variables - hormone concentration and the timing of its administration, the copulatory plug presence and individual male used to mating – could be predictive factors on the mouse embryo production. Females were distributed in four groups (cross-over design) related to scheduled superstimulation treatment (1300h or 1700h) and eCG/hCG administered concentration (5 or 10IU). After the hCG treatment, females were put to mate. On the next morning it was verified the presence of a copulatory plug (D0.5). Embryo recovery was performed from D2.5 to D4.5 by flushing the oviducts and uterine horns. Total structures recovered (TSR) and the viable embryos (VE) were classified by its morphology. Viability rate (VR) was calculated with VE in relation to TSR (x100). Group comparison was analyzed with 5% of significance. There were no significant differences among groups, even when only main effects were analyzed (hormone concentration and timing of its administration). There was significant difference in VR from animals with or without plug and from the worst and best males used. It was concluded that neither the hormone concentration nor timing of its administration - or their association – was significant as predictive factors for the embryo production. However, the plug presence was related to higher VR.
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Pós-graduação em Agronomia (Entomologia Agrícola) - FCAV
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The present study aimed to analyze the floristic and structural descriptors of tree species natural regeneration in a forest sector with synchronized bamboo (Merostachys multiramea Hackel) die-off (CT) and an adjacent area with continuous canopy cover (ST) in an araucaria forest fragment in the municipality of Lages, Santa Catarina state. A total of 14, 5x5m, plots (six plots in CT sector and eight in ST sector) were allocated, where all tree species regenerative individual with circumference at breast height smaller than 15cm and height higher than 25cm was measured (diameter at soil level) and identified. The richest families were: Myrtaceae (nine), Solanaceae (six) and Aquifoliaceae (four). The Shannon Diversity Index in ST and CT sectors were respectively 2.73 and 2.31. The species with the highest importance values in CT sector were Solanum variabile, Piptocarpha angustifolia, Mimosa scabrella, Jacaranda puberula and Solanum pseudoquina. In ST sector, the species with highest importance values were Myrsine lorentziana, Casearia decandra, Cinnamodendron dinisii, Drimys brasiliensis and Ilex paraguariensis. The results showed that the synchronized bamboo die-off influenced the spatial variation in the floristic and structural descriptors of the tree species natural regeneration.