Not for Designers: On the Inadequacies of EU Design Law and How to Fix It

Design rights represent an interesting example of how the EU legislature has successfully regulated an otherwise heterogeneous field of law. Yet this type of protection is not for all. The tools created by EU intervention have been drafted paying much more attention to the industry sector rather than to designers themselves. In particular, modern, digitally based, individual or small-sized, 3D printing, open designers and their needs are largely neglected by such legislation. There is obviously nothing wrong in drafting legal tools around the needs of an industrial sector with an important role in the EU economy, on the contrary, this is a legitimate and good decision of industrial policy. However, good legislation should be fair, balanced, and (technologically) neutral in order to offer suitable solutions to all the players in the market, and all the citizens in the society, without discriminating the smallest or the newest: the cost would be to stifle innovation. The use of printing machinery to manufacture physical objects created digitally thanks to computer programs such as Computer-Aided Design (CAD) software has been in place for quite a few years, and it is actually the standard in many industrial fields, from aeronautics to home furniture. The change in recent years that has the potential to be a paradigm-shifting factor is a combination between the opularization of such technologies (price, size, usability, quality) and the diffusion of a culture based on access to and reuse of knowledge. We will call this blend Open Design. It is probably still too early, however, to say whether 3D printing will be used in the future to refer to a major event in human history, or instead will be relegated to a lonely Wikipedia entry similarly to ³Betamax² (copyright scholars are familiar with it for other reasons). It is not too early, however, to develop a legal analysis that will hopefully contribute to clarifying the major issues found in current EU design law structure, why many modern open designers will probably find better protection in copyright, and whether they can successfully rely on open licenses to achieve their goals. With regard to the latter point, we will use Creative Commons (CC) licenses to test our hypothesis due to their unique characteristic to be modular, i.e. to have different license elements (clauses) that licensors can choose in order to adapt the license to their own needs.”

Scoping Electronic Communication Privacy Rules: Data, Services and Values

We use electronic communication networks for more than simply traditional telecommunications: we access the news, buy goods online, file our taxes, contribute to public debate, and more. As a result, a wider array of privacy interests is implicated for users of electronic communications networks and services. . This development calls into question the scope of electronic communications privacy rules. This paper analyses the scope of these rules, taking into account the rationale and the historic background of the European electronic communications privacy framework. We develop a framework for analysing the scope of electronic communications privacy rules using three approaches: (i) a service-centric approach, (ii) a data-centric approach, and (iii) a value-centric approach. We discuss the strengths and weaknesses of each approach. The current e-Privacy Directive contains a complex blend of the three approaches, which does not seem to be based on a thorough analysis of their strengths and weaknesses. The upcoming review of the directive announced by the European Commission provides an opportunity to improve the scoping of the rules.

Comparison of the toxicity of diesel exhaust produced by bio- and fossil diesel combustion in human lung cells in vitro

Alternative fuels are increasingly combusted in diesel- and gasoline engines and the contribution of such exhausts to the overall air pollution is on the rise. Recent findings on the possible adverse effects of biodiesel exhaust are contradictive, at least partly resulting from the various fuel qualities, engine types and different operation conditions that were tested. However, most of the studies are biased by undesired interactions between the exhaust samples and biological culture media. We here report how complete, freshly produced exhausts from fossil diesel (B0), from a blend of 20% rapeseed-methyl ester (RME) and 80% fossil diesel (B20) and from pure rapeseed methyl ester (B100) affect a complex 3D cellular model of the human airway epithelium in vitro by exposing the cells at the air–liquid interface. The induction of pro-apoptotic and necrotic cell death, cellular morphology, oxidative stress, and pro-inflammatory responses were assessed. Compared to B0 exhaust, B20 exhaust decreased oxidative stress and pro-inflammatory responses, whereas B100 exhaust, depending on exposure duration, decreased oxidative stress but increased pro-inflammatory responses. The effects are only very weak and given the compared to fossil diesel higher ecological sustainability of biodiesel, it appears that – at least RME – can be considered a valuable alternative to pure fossil diesel.

Contrasts, Contacts, and Interconnections — Tel Kinrot as an Early Iron Age Key Site in the Northern Jordan Rift Valley at the Dawn of the 1st Millennium BCE

Ancient Kinneret (Tēl Kinrōt [Hebrew]; Tell el-ʿOrēme [Arabic]) is located on a steep limestone hill on the northwestern shores of the Sea of Galilee (2508.7529 [NIG]). The site, whose settlement history began sometime during the Pottery-Neolithic or the early Chalcolithic period, is emerging as one of the major sites for the study of urban life in the Southern Levant during the Early Iron Age (c. 1130–950 BCE). Its size, accessibility by major trade routes, and strategic location between different spheres of cultural and political influence make Tēl Kinrōt an ideal place for studying the interaction of various cultures on urban sites, as well as to approach questions of ethnicity and regionalism during one of the most debated periods in the history of the ancient Levant. The paper will briefly discuss the settlement history of the site during the Early Iron Age. However, the main focus will lie on the material culture of the late Iron Age IB city that rapidly evolved to a regional center during the transition from the 11th to the 10th century BCE. During this period, ancient Kinneret features a multitude of cultural influences that reach from Egypt via the Central Hill Country until the Northern parts of Syria and the Amuq region. While there are indisputably close ties with the ‘Aramaean’ realm, there are also strong indications that there were – at the same time – vivid socio-economic links with the West, i.e. the Southern and Northern Mediterranean coasts and their hinterland. It will be argued that the resulting ‘cultural blend’ is a typical characteristic of the material culture of the Northern Jordan Rift Valley in the advent of the emerging regional powers of the Iron Age II.

Plant strengtheners enhance parasitoid attraction to herbivore-damaged cotton via qualitative and quantitative changes in induced volatiles

BACKGROUND Herbivore-damaged plants release a blend of volatile organic compounds (VOCs) that differs from undamaged plants. These induced changes are known to attract the natural enemies of the herbivores and therefore are expected to be important determinants of the effectiveness of biological control in agriculture. One way of boosting this phenomenon is the application of plant strengtheners, which has been shown to enhance parasitoid attraction in maize. It is unclear whether this is also the case for other important crops. RESULTS The plant strengtheners BTH [benzo (1,2,3) thiadiazole-7-carbothioic acid S-methyl ester] and laminarin were applied to cotton plants, and the effects on volatile releases and the attraction of three hymenopteran parasitoids, Cotesia marginiventris, Campoletis sonorensis and Microplitis rufiventris, were studied. After treated and untreated plants were induced by real or simulated caterpillar feeding, it was found that BTH treatment increased the attraction of the parasitoids, whereas laminarin had no significant effect. BTH treatment selectively increased the release of two homoterpenes and reduced the emission of indole, the latter of which had been shown to interfere with parasitoid attraction in earlier studies. Canonical variate analyses of the data show that the parasitoid responses were dependent on the quality rather than the quantity of volatile emission in this tritrophic interaction. CONCLUSION Overall, these results strengthen the emerging paradigm that induction of plant defences with chemical elicitors such as BTH could provide a sustainable and environmentally friendly strategy for biological control of pests by enhancing the attractiveness of cultivated plants to natural enemies of insect herbivores. © 2014 Society of Chemical Industry

Two enzymes responsible for the formation of herbivore-induced volatiles of maize, the methyltransferase AAMT1 and the terpene synthase TPS23, are regulated by a similar signal transduction pathway

Herbivore-induced volatiles play an important role in the indirect defense of plants. After herbivore damage, volatiles are released from the plant and can attract herbivore enemies that protect the plant from additional damage. The herbivore-induced volatile blend is complex and usually consists of mono- and sesquiterpenes, aromatic compounds, and indole. Although these classes of compounds are generally produced at different times after herbivore damage, the release of the terpene (E)-β-caryophyllene and the aromatic ester methyl anthranilate appear to be tightly coordinated. We have studied the herbivore induction patterns of two terpene synthases from Zea mays L. (Poaceae), TPS23 and TPS10, as well as S-adenosyl-L-methionine:anthranilic acid carboxyl methyltransferases (AAMT1), which are critical for the production of terpenes and anthranilate compounds, respectively. The transcript levels of tps23 and aamt1 displayed the same kinetics after damage by the larvae of Spodoptera littoralis (Boisduval) (Lepidoptera: Noctuidae), and showed the same organ-specific and haplotype-specific expression patterns. Despite its close functional relation to TPS23, the terpene synthase TPS10 is not expressed in roots and does not display the haplotype-specific expression pattern. The results indicate that the same JA-mediated signaling cascade maycontrol the production of both the terpene (E)-β-caryophyllene and aromatic ester methyl anthranilate.

Herbivore-Induced Plant Volatiles Can Serve as Host Location Cues for a Generalist and a Specialist Egg Parasitoid

Herbivore-induced plant volatiles are important host finding cues for larval parasitoids, and similarly, insect oviposition might elicit the release of plant volatiles functioning as host finding cues for egg parasitoids. We hypothesized that egg parasitoids also might utilize HIPVs of emerging larvae to locate plants with host eggs. We, therefore, assessed the olfactory response of two egg parasitoids, a generalist, Trichogramma pretiosum (Tricogrammatidae), and a specialist, Telenomus remus (Scelionidae) to HIPVs. We used a Y-tube olfactometer to tests the wasps’ responses to volatiles released by young maize plants that were treated with regurgitant from caterpillars of the moth Spodoptera frugiperda (Noctuidae) or were directly attacked by the caterpillars. The results show that the generalist egg parasitoid Tr. pretiosum is innately attracted by volatiles from freshly-damaged plants 0–1 and 2–3 h after regurgitant treatment. During this interval, the volatile blend consisted of green leaf volatiles (GLVs) and a blend of aromatic compounds, mono- and homoterpenes, respectively. Behavioral assays with synthetic GLVs confirmed their attractiveness to Tr. pretiosum. The generalist learned the more complex volatile blends released 6–7 h after induction, which consisted mainly of sesquiterpenes. The specialist T. remus on the other hand was attracted only to volatiles emitted from fresh and old damage after associating these volatiles with oviposition. Taken together, these results strengthen the emerging pattern that egg and larval parasitoids behave in a similar way in that generalists can respond innately to HIPVs, while specialists seems to rely more on associative learning.

The Role of Fresh versus Old Leaf Damage in the Attraction of Parasitic Wasps to Herbivore-Induced Maize Volatiles

The odor produced by a plant under herbivore attack is often used by parasitic wasps to locate hosts. Any type of surface damage commonly causes plant leaves to release so-called green leaf volatiles, whereas blends of inducible compounds are more specific for herbivore attack and can vary considerably among plant genotypes. We compared the responses of naïve and experienced parasitoids of the species Cotesia marginiventris and Microplitis rufiventris to volatiles from maize leaves with fresh damage (mainly green leaf volatiles) vs. old damage (mainly terpenoids) in a six-arm olfactometer. These braconid wasps are both solitary endoparasitoids of lepidopteran larvae, but differ in geographical origin and host range. In choice experiments with odor blends from maize plants with fresh damage vs. blends from plants with old damage, inexperienced C. marginiventris showed a preference for the volatiles from freshly damaged leaves. No such preference was observed for inexperienced M. rufiventris. After an oviposition experience in hosts feeding on maize plants, C. marginiventris females were more attracted by a mixture of volatiles from fresh and old damage. Apparently, C. marginiventris has an innate preference for the odor of freshly damaged leaves, and this preference shifts in favor of a blend containing a mixture of green leaf volatiles plus terpenoids, after experiencing the latter blend in association with hosts. M. rufiventris responded poorly after experience and preferred fresh damage odors. Possibly, after associative learning, this species uses cues that are more directly related with the host presence, such as volatiles from host feces, which were not present in the odor sources offered in the olfactometer. The results demonstrate the complexity of the use of plant volatiles by parasitoids and show that different parasitoid species have evolved different strategies to exploit these signals.

Enhanced in vivo angiogenesis within a model tissue engineered construct using biodegradable microspheres containing encapsulated VEGF

Introduction. Tissue engineering techniques offer a potential means to develop a tissue engineered construct (TEC) for the treatment of tissue and organ deficiencies. However, a lack of adequate vascularization is a limiting factor in the development of most viable engineered tissues. Vascular endothelial growth factor (VEGF) could aid in the development of a viable vascular network within TECs. The long-term goals of this research are to develop clinically relevant, appropriately vascularized TECs for use in humans. This project tested the hypothesis that the delivery of VEGF via controlled release from biodegradable microspheres would increase the vascular density and rate of angiogenesis within a model TEC. ^ Materials and methods. Biodegradable VEGF-encapsulated microspheres were manufactured using a novel method entitled the Solid Encapsulation/Single Emulsion/Solvent Extraction technique. Using a PLGA/PEG polymer blend, microspheres were manufactured and characterized in vitro. A model TEC using fibrin was designed for in vivo tissue engineering experimentation. At the appropriate timepoint, the TECs were explanted, and stained and quantified for CD31 using a novel semi-automated thresholding technique. ^ Results. In vitro results show the microspheres could be manufactured, stored, degrade, and release biologically active VEGF. The in vivo investigations revealed that skeletal muscle was the optimal implantation site as compared to dermis. In addition, the TECs containing fibrin with VEGF demonstrated significantly more angiogenesis than the controls. The TECs containing VEGF microspheres displayed a significant increase in vascular density by day 10. Furthermore, TECs containing VEGF microspheres had a significantly increased relative rate of angiogenesis from implantation day 5 to day 10. ^ Conclusions. A novel technique for producing microspheres loaded with biologically active proteins was developed. A defined concentration of microspheres can deliver a quantifiable level of VEGF with known release kinetics. A novel model TEC for in vivo tissue engineering investigations was developed. VEGF and VEGF microspheres stimulate angiogenesis within the model TEC. This investigation determined that biodegradable rhVEGF 165-encapsulated microspheres increased the vascular density and relative rate of angiogenesis within a model TEC. Future applications could include the incorporation of microvascular fragments into the model TEC and the incorporation of specific tissues, such as fat or bone. ^

The Effects Of Reinforcement Inclusions On Wear Tolerance, Playing Quality And Physical Properties In A Silt Loam And Sand Rootzone Matrix

Reinforcement inclusions have been advocated to alleviate wear, compaction, and unstable surfaces in sports fields, but little research on the effects of these materials has been conducted in the USA. Experiments were established on a native silt loam and a sand rootzone matrix, seeded with a Kentucky bluegrass (Poa pratensis L.) blend, at the Joseph Troll Turf Research Center, University of Massachusetts, Amherst, USA to determine the effects of reinforcement inclusions on wear, surface hardness, traction, ball roll, ball bounce resilience, water infiltration rate, soil bulk density, air porosity, total porosity, and root weights. Three types of reinforcement inclusions (Sportgrass, Netlon, Turfgrids) were tested along with a non-reinforced control in a three year study. The treatments were set out in a randomized complete block design with four replications in both soils. No inclusion provided less wear or greater infiltration or air-filled porosity relative to the control. Reinforcement inclusions showed significant differences, however, in surface hardness, traction, and ball roll relative to the control, although this varied with the time of year. Infiltration rates, airfilled porosity, total pore space, bulk density, hardness, traction, ball roll, and ball rebound were greater on the sand rootzone than on the silt loam. Significant correlations were present between soil bulk density, surface hardness, traction, and ball roll. Based on our study, the use of reinforcement inclusions to provide better wear tolerance for sand or native soil athletic fields is not warranted. Certain playing surface characteristics, however, may be slightly improved with the use of reinforcement inclusions. The use of sands for sports surfaces is justified based upon the improvement in playing quality characteristics and soil physical properties important to a good playing surface.

Diseño gráfico de etiquetas para envases de vino : definición de descriptores para un análisis de componentes sintácticas

Las gráficas de etiquetas para envases de vino son diseñadas a partir de características sintácticas, semánticas y pragmáticas. Este trabajo tiene por objetivos realizar una recopilación, clasificación, análisis y jerarquización de los componentes de la configuración de etiquetas de vino, y además, proveer un instrumento que permita un análisis de estas piezas gráficas, de manera individual, con carácter de sistema o en comparación. Podrá ser aplicado por los profesionales que diseñan etiquetas y envases, por docentes en el campo del diseño y en guías para el público usuario. (…) “los diseñadores nos convertimos en el nexo simbólico entre la calidad de los productos elaborados por nuestros clientes y la calidad de vida de aquéllos que los disfrutan. Somos los que preparamos la logística simbólica que explicita estéticamente lo que un buen vino necesita para llamar la atención. Se trata de crear la imagen que represente fielmente al conjunto de atributos del vino, y de resaltar visualmente esta red de placeres que están presentes en él. Sólo así se logra una relación de confianza con la marca". (Santiago Zemma, 2005).

Estrategias de orientación educativa y ocupacional en Adultos Mayores

El presente trabajo se propone articular el Modelo Teórico Operativo en Orientación, desarrollado por la Dra. Gavilán y el Modelo de Envejecimiento Activo con el objetivo de profundizar los aportes que pueden realizarse desde la Orientación y diseñar estrategias de intervención acordes a la población objeto de estudio. Presenta continuidad temática con los proyectos de investigación ?La Orientación en el Nuevo Modelo de Envejecimiento Activo: elecciones educativas, laborales, personales y sociales? y ?Estrategias orientadoras para la elaboración de proyectos en adultos mayores?, llevados a cabo como becaria de la Secretaría de Ciencia y Técnica de la Universidad Nacional de La Plata. Surge de la insuficiente producción teórica al respecto, así como de la inexistencia de enfoques, programas y estrategias de intervenciones de este tipo con sujetos adultos mayores a nivel local, a diferencia de lo que sucede con otras etapas evolutivas, fundamentalmente la adolescencia. Asimismo, son escasos los desarrollos internacionales sobre la temática. A los fines de esta investigación, se han tomado en consideración datos relativos a la expectativa de la vida de las personas, la transición demográfica de nuestro país y los lineamientos de organismos nacionales e internacionales en cuanto a la promoción de un envejecimiento activo y saludable. Con respecto a la Orientación Vocacional se adopta el enfoque de la orientación continua, es decir, como un proceso a lo largo de la vida. La insuficiencia de investigaciones sobre las cuestiones planteadas, pone de relieve el interés y el aporte de esta investigación, en la medida en que comporta una apertura a nuevas oportunidades de desarrollo y realización personal de un porcentaje significativo de la población, destinada a facilitar la comprensión de la elaboración de proyectos en la etapa considerada. El estudio sobre la vejez ha tomado gran relevancia desde las distintas disciplinas ya que el envejecimiento poblacional plantea nuevos escenarios y nuevos desafíos a la ciencia y a la sociedad en general. El fenómeno de transformación demográfica ha dado lugar a numerosas investigaciones y a diversas políticas para brindar una mejor calidad de vida a las personas mayores desde distintos sectores. Como fenómeno social requiere de una mirada desde el paradigma de la complejidad, de un abordaje interdisciplinario y del diseño de estrategias integrales

Estrategias de orientación educativa y ocupacional en Adultos Mayores

El presente trabajo se propone articular el Modelo Teórico Operativo en Orientación, desarrollado por la Dra. Gavilán y el Modelo de Envejecimiento Activo con el objetivo de profundizar los aportes que pueden realizarse desde la Orientación y diseñar estrategias de intervención acordes a la población objeto de estudio. Presenta continuidad temática con los proyectos de investigación ?La Orientación en el Nuevo Modelo de Envejecimiento Activo: elecciones educativas, laborales, personales y sociales? y ?Estrategias orientadoras para la elaboración de proyectos en adultos mayores?, llevados a cabo como becaria de la Secretaría de Ciencia y Técnica de la Universidad Nacional de La Plata. Surge de la insuficiente producción teórica al respecto, así como de la inexistencia de enfoques, programas y estrategias de intervenciones de este tipo con sujetos adultos mayores a nivel local, a diferencia de lo que sucede con otras etapas evolutivas, fundamentalmente la adolescencia. Asimismo, son escasos los desarrollos internacionales sobre la temática. A los fines de esta investigación, se han tomado en consideración datos relativos a la expectativa de la vida de las personas, la transición demográfica de nuestro país y los lineamientos de organismos nacionales e internacionales en cuanto a la promoción de un envejecimiento activo y saludable. Con respecto a la Orientación Vocacional se adopta el enfoque de la orientación continua, es decir, como un proceso a lo largo de la vida. La insuficiencia de investigaciones sobre las cuestiones planteadas, pone de relieve el interés y el aporte de esta investigación, en la medida en que comporta una apertura a nuevas oportunidades de desarrollo y realización personal de un porcentaje significativo de la población, destinada a facilitar la comprensión de la elaboración de proyectos en la etapa considerada. El estudio sobre la vejez ha tomado gran relevancia desde las distintas disciplinas ya que el envejecimiento poblacional plantea nuevos escenarios y nuevos desafíos a la ciencia y a la sociedad en general. El fenómeno de transformación demográfica ha dado lugar a numerosas investigaciones y a diversas políticas para brindar una mejor calidad de vida a las personas mayores desde distintos sectores. Como fenómeno social requiere de una mirada desde el paradigma de la complejidad, de un abordaje interdisciplinario y del diseño de estrategias integrales

Estrategias de orientación educativa y ocupacional en Adultos Mayores

El presente trabajo se propone articular el Modelo Teórico Operativo en Orientación, desarrollado por la Dra. Gavilán y el Modelo de Envejecimiento Activo con el objetivo de profundizar los aportes que pueden realizarse desde la Orientación y diseñar estrategias de intervención acordes a la población objeto de estudio. Presenta continuidad temática con los proyectos de investigación ?La Orientación en el Nuevo Modelo de Envejecimiento Activo: elecciones educativas, laborales, personales y sociales? y ?Estrategias orientadoras para la elaboración de proyectos en adultos mayores?, llevados a cabo como becaria de la Secretaría de Ciencia y Técnica de la Universidad Nacional de La Plata. Surge de la insuficiente producción teórica al respecto, así como de la inexistencia de enfoques, programas y estrategias de intervenciones de este tipo con sujetos adultos mayores a nivel local, a diferencia de lo que sucede con otras etapas evolutivas, fundamentalmente la adolescencia. Asimismo, son escasos los desarrollos internacionales sobre la temática. A los fines de esta investigación, se han tomado en consideración datos relativos a la expectativa de la vida de las personas, la transición demográfica de nuestro país y los lineamientos de organismos nacionales e internacionales en cuanto a la promoción de un envejecimiento activo y saludable. Con respecto a la Orientación Vocacional se adopta el enfoque de la orientación continua, es decir, como un proceso a lo largo de la vida. La insuficiencia de investigaciones sobre las cuestiones planteadas, pone de relieve el interés y el aporte de esta investigación, en la medida en que comporta una apertura a nuevas oportunidades de desarrollo y realización personal de un porcentaje significativo de la población, destinada a facilitar la comprensión de la elaboración de proyectos en la etapa considerada. El estudio sobre la vejez ha tomado gran relevancia desde las distintas disciplinas ya que el envejecimiento poblacional plantea nuevos escenarios y nuevos desafíos a la ciencia y a la sociedad en general. El fenómeno de transformación demográfica ha dado lugar a numerosas investigaciones y a diversas políticas para brindar una mejor calidad de vida a las personas mayores desde distintos sectores. Como fenómeno social requiere de una mirada desde el paradigma de la complejidad, de un abordaje interdisciplinario y del diseño de estrategias integrales

Preliminary Study and Proposal for Restoring a Jesuit College at Saragossa, Spain

A historical study and a construction pathology survey were conducted prior to proposing a solution for restoring the upper windows on the south side of Old San Carlos College at Saragossa (16th-17th centuries), wich had been forteited to add a third storey to the cloister. Althought initially designed to a simple large hall format, the church is a harmonius blend of Aragonese Gothic architecture and typical Jesuit scheme, consisting in a central nave flanket by chapel-confessional and raised galleries for the community. A subsequent enlargement of the roof, wich rests on the original framing over the central nave, reduced the mechanical strength of the principal rafters on the opposite side, prompting a concomitant imbalance of forces that has affected the entire structure. In view of the foregoing, in addition to restituting the upper window, the proposal solution envisages restoring the roof over the central nave to its original design, and with the interior lighting in the church.