Is cryptosporidiosis an underestimated disease in cats?

Studies on the occurrence of Cryptosporidium spp. in cats are still scarce. In this literature review, we address epidemiological and clinical aspects, as well as diagnostic methods, therapeutic behavoiur, and control and prevention measures for this disease in cats, with the aim of investigating if cryptosporidiosis is an underestimated disease in the laboratory routine and in small animal medical clinics.

Coinfection by toxoplasma gondii and leishmania spp. in domestic cats (Felis catus) in State of Mato Grosso do Sul

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação do selante de fibrina como arcabouço para células tronco em fígados cirróticos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Epidemiologia molecular do vírus da Hepatite C: análise comparativa de diferentes regiões subgenômicas aplicadas a estudos de associação genética

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Conscientizar para o bem-estar animal: posse responsável

The community awareness on responsible ownership associated with public policies is key to the promotion of animal welfare. Most cities have a large population of dogs and cats wandering causing serious health problems and abuse. This project aimed to guide and inform the population aimed at animal welfare with the simple and direct approach to issues related to responsible ownership, management, nature conservation and zoonoses. The methodology developed to approach the project in two modules: the I and II, along public and private Elementary and High Schools in Araçatuba. Module I (Mod.I) is basedon the use of puppet theater and musicals, considering the target audience children 3-10 years and the second module (Mod 2) consists of presentations of lectures by undergraduate and graduate course of Veterinary Medicine FMVA UNESP campus Araçatuba, being the target audience of High School teenagers. Data collection proceeded by questionnaires, with questions regarding the care and practices to pets. The results revealed that there is a lack of information about animal welfare practice.

Orientação sobre posse responsável em uma área endêmica para leishmaniose visceral canina

The purpose of this work was to provide guidance to householders in the responsible care of their pets, in a region where canine visceral leishmaniasis is endemic. Questionnaires on responsible ownership and the control of this disease were completed by owners of dogs and cats in the city of Araçatuba, São Paulo State, Brazil, in order to evaluate their level of knowledge. Based on the identified deficiencies, the project team provided the owners of the pets with individual guidance at home, focusing on the most critical issues. Concerning nutrition, 70.45% (62/88) of owners provided pet food only, 27.28% (24/88) administered a mixed diet, and 2.27% (2/88) provided homemade food. Additionally, 78.41% (69/88) did not permit the consumption of raw meat, rare meat, or bones. 9.09% (8/88) of owners allowed their pets to wander the neighborhood alone. Among dogs, 14.77% (13/88) had never been clinically tested by a qualified professional, and 6.82% (6/88) and 15.91% (14/88) had never received any kind of vaccine or vermifuge, respectively. In relation to population control, only 20.45% (18/88) of the dogs had been sterilized. It was also observed that 25% (22/88) of owners had already had canine visceral leishmaniasis seropositive dogs in their homes. 54.55% (12/22) of these owners had referred their pets to veterinary clinics for euthanasia, 22.73% (5/22) had used the services of the city’s animal disease control center, and 18.18% (4/22) had paid for private treatment. Nevertheless, 35.23% (31/88) of the dogs had never been submitted to tests for infection diagnosis. From the results obtained, it could be inferred that the individuals who participated in this study were poorly informed concerning basic pet care, demonstrating a need to implement community awareness campaigns for the responsible ownership of pets.

Helmintoses zoonóticas transmitidas pelo consumo inadequado de peixes

Among the major food-borne parasitic zoonoses, the helminthiasis transmitted by consumption of fish have been highlighted because they involve a large number of individuals in many regions of the world in recent years. In the past, these parasitosis were restricted to underdeveloped nations or with peculiar eating habits; however the process of globalization of food production, the increased international travel and consumption of fish for their nutritional benefits caused the expansion into new areas, which had never before been recorded, making it a serious public health problem in some countries. This review discuss the main helminths transmitted by eating raw or undercooked fish, in order to alert the public, the scientific community and health authorities about their risks to human health, as well as stimulate the realization of new researches that contributes to a greater knowledge of the epidemiological situation in the country of these parasites and the development of strategies for prevention and control of them.

Ações educativas para o controle de vetores da dengue e leishmaniose visceral

Results of educative actions on the control of vectors for dengue and leishmaniasis were evaluated by using an online semi-present course directed to teachers from Fundamental I Education level in Araçatuba-SP. 40 teachers from municipal schools located on geographical areas of town with higher occurrence of dengue and leishmaniasis cases, attended to the course, which consisted in a conceptual part directed to specific subjects such as vector borne and zoonotic diseases, responsible ownership of pets and health education and a practical phase, directed to execution and application of educative projects in the target schools. Data about the teacher’s specific knowledge, before and after the attendance to the course, were submitted to the Wilcoxon test with a 5% of significant level. The application of practical educative projects was evaluated by multiplicative actions involving target public. Tests showed statistically significant increase in the knowledge about the studied diseases (p<0.0001) after the course, especially on questions related to etiological agent, clinical symptoms on man and animals and prevention. Activities of knowledge multiplication envolved teachers and students which detected the problems and promoted education actions in their neighborhood as stage performing, group cleaning activities and elaboration and distribution of folders during a student pared. In conclusion, educative actions direct to the control of diseases vectors using a semi-present course, provides new knowledge to the teachers, impelling them to motivate their students to adopt vectors control measures and environmental cares and to sensitive the community to collaborate with control diseases.

Avaliação laboratorial da cinomose canina: estudo retrospectivo de 25 casos no município de Araçatuba-SP

Canine Distemper is a contagious, severe and multisystemic disease caused by a virus from Morbillivírus genus. The virus is distributed worldwide and it presents a high lethality rate, affecting mainly dogs. The diagnosis is based on clinical signs associated with hematological fi ndings. The observation of Lentz bodies in erythrocytes and leukocytes is the defi nitive diagnosis for the disease. The aim of this work was to test the hypothesis that the hematological profi le in dogs positive for canine distemper differs according to blood cell type presenting Lentz bodies. For this purpose, 25 dogs positive for the disease were evaluated at the Veterinary Hospital “Luís Quintiliano de Oliveira” UNESP, Araçatuba city. The diagnosis was based on the observation of Lentz bodies in blood smears. Fromthe total, 64% of dogs presented anemia, 16% leucopenia and 12% leukocytosis. Lymphopenia occurred in 76% of dogs. Viral inclusions were observed solely in neutrophils (32%), lymphocytes (28%) and erythrocytes (12%). Concomitant observation occurred in lymphocytes and erythrocytes (4 %), in lymphocytes and neutrophils (12%), in neutrophils and monocytes (4%) and in neutrophils and erythrocytes (4%). In an isolated case Lentz bodies were observed simultaneously in neuthrophils, monocytes and lymphocytes. In conclusion, hematological profi le is not associated with the presence of viral inclusion in a particular cell type.

Detecção precoce e quantificação de vírus da cinomose por PCR quantitativa em Tempo Real (qPCR) em diferentes tecidos e fluidos de um cão

A cinomose é uma doença de desafio diagnóstico, especialmente quando não há histórico de vacinação. O objetivo deste estudo foi detectar e quantificar partículas virais de cinomose em diferentes fluidos e tecidos biológicos de um cão, determinando o melhor tecido para diagnóstico viral ante mortem na fase de viremia. Atendeu-se um cão adulto com manifestações clínicas inespecíficas e corpúsculos de Sinegaglia Lentz em linfócitos. Amostras post mortem foram submetidas a PCR em tempo real (qPCR), que demonstrou RNA viral em concentrações de (x105) em líquor (1.216), bexiga (1.009), cérebro (605), sangue (572), cerebelo (523), rins (373), fígado (257), pulmões (191), estômago (154), terceira pálpebra (70) e urina (2,1). A técnica de qPCR permitiu confirmar a infecção pelo vírus, descartando vacinação recente. A amostra de líquor mostrou-se representativa para diagnóstico molecular de fase aguda de cinomose no animal estudado.

Toll-Like recepctors (TLRs) and retinoic acid inducible gene – I (RIG-I) activation by viral analogs in bovine endometrial cells

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Estudo da ação de derivados semi-sintéticos de curcumina em linhagens celulares de câncer humano

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Diagnóstico de situação epidemiológica da Leishmaniose visceral canina em Rio Verde-GO

Pós-graduação em Medicina Veterinária - FCAV

Participação de gambás e cães domiciliados como reservatórios de Leishmania infantum e Trypanosoma cruzi georreferenciados nos municípios da Regional de Saúde de Três Lagoas - MS

Pós-graduação em Doenças Tropicais - FMB

Análise do efeito in vitro de acridonas na replicação do Vírus da Hepatite C

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)