Safety and efficacy of angioplasty with intracoronary stenting in patients with unstable coronary syndromes. Comparison with stable coronary syndromes

OBJECTIVE: To assess safety and efficacy of coronary angioplasty with stent implantation in unstable coronary syndromes. METHODS: Retrospective analysis of in-hospital and late evolution of 74 patients with unstable coronary syndromes (unstable angina or infarction without elevation of the ST segment) undergoing coronary angioplasty with stent placement. These 74 patients were compared with 31 patients with stable coronary syndromes (stable angina or stable silent ischemia) undergoing the same procedure. RESULTS: No death and no need for revascularization of the culprit artery occurred in the in-hospital phase. The incidences of acute non-Q-wave myocardial infarction were 1.4% and 3.2% (p=0.6) in the unstable and stable coronary syndrome groups, respectively. In the late follow-up (11.2±7.5 months), the incidences of these events combined were 5.7% in the unstable coronary syndrome group and 6.9% (p=0.8) in the stable coronary syndrome group. In the multivariate analysis, the only variable with a tendency to significance as an event predictor was diabetes mellitus (p=0.07; OR=5.2; 95% CI=0.9-29.9). CONCLUSION: The in-hospital and late evolutions of patients with unstable coronary syndrome undergoing angioplasty with intracoronary stent implantation are similar to those of the stable coronary syndrome group, suggesting that this procedure is safe and efficacious when performed in unstable coronary syndrome patients.

“Safety and health” as a criterion in the choice of tunneling method

Risk management is of paramount importance in the success of tunnelling works and is linked to the tunnelling method and to the constraints of the works. Sequencial Excavation Method (SEM) and Tun-nel Boring Machine (TBM) method have been competing for years. This article, part of a wider study on the influence of the â Safety and Healthâ criterion in the choice of method, reviews the existing literature about the criteria usually employed to choose the tunnelling method and on the criterion â Safety and Healthâ . This crite-rion is particularly important, due to the financial impacts of work accidents and occupational diseases. This article is especially useful to the scientific and technical community, since it synthesizes the relevance of each one of the choice criteria used and it shows why â Safety and Healthâ must be a criterion in the decision mak-ing process to choose the tunnelling method.

A multicenter, open-label study of the efficacy and safety of telmisartan in mild to moderate hypertensive patients

OBJECTIVE: To evaluate the efficacy and tolerability of telmisartan, given once a day to patients with mild to moderate hypertension, as well as to assess the 24-hour blood pressure profile with ABPM. METHODS: Initially, 163 patients over 18 were selected, regardless of sex, with blood pressure levels >140/90mmHg at visit 1, which was confirmed at visit 2. One hundred thirty-four patients completed the study. After a 4-week placebo run-in phase, telmisartan 40mg/daily was given for 6 weeks. In those patients whose blood pressure (BP) levels were lower than 140/90mmHg, the same dosage was kept for an additional period of 6 weeks. For those who had BP higher than 140/90mmHg, the dosage was increased to 80mg/daily. Sixty-two patients were included in a subgroup that underwent ABPM 3 different times during the study. RESULTS: In the overall group, blood pressure reduction ranged from 162.3±14.5/101.3±5.75 mmHg (baseline) to 147.3±20.1/90.8±10.9 mmHg (week 12) (p<0.05). Mean blood pressure decreases were 14.4mmHg for systolic BP and 10.3mmHg for diastolic BP, after 12 weeks of active treatment. A subanalysis showed that 47 (35%) patients took telmisartan 40mg throughout the study and 81 (65%) had the dosage increased to 80mg daily. Using ABPM, an 8-mmHg reduction in systolic BP as well as a 5-mmHg reduction in diastolic BP were observed, when compared with baseline values in the final 6 hours (18-24 hours after the last dose of study medication). CONCLUSION: Our results confirm that telmisartan given once a day is effective in reducing blood pressure levels in mild to moderate hypertensive patients. This reduction occurs in a sustained and gradual manner during a 24-hour period confirmed by ABPM.

L'Illustration horticole : journal spécial des serres et des jardins, ou choix raisonné des plantes les plus intérressantes sous le rapport ornemental, comprenant leur histoire complete, leur description comparée, leur figure et leur culture /

v.1 (1854)

L'Illustration horticole : journal spécial des serres et des jardins, ou choix raisonné des plantes les plus intérressantes sous le rapport ornemental, comprenant leur histoire complete, leur description comparée, leur figure et leur culture /

v.2 (1855)

L'Illustration horticole : journal spécial des serres et des jardins, ou choix raisonné des plantes les plus intérressantes sous le rapport ornemental, comprenant leur histoire complete, leur description comparée, leur figure et leur culture /

v.3 (1856)

L'Illustration horticole : journal spécial des serres et des jardins, ou choix raisonné des plantes les plus intérressantes sous le rapport ornemental, comprenant leur histoire complete, leur description comparée, leur figure et leur culture /

v.4 (1857)

L'Illustration horticole : journal spécial des serres et des jardins, ou choix raisonné des plantes les plus intérressantes sous le rapport ornemental, comprenant leur histoire complete, leur description comparée, leur figure et leur culture /

v.5 (1858)

L'Illustration horticole : journal spécial des serres et des jardins, ou choix raisonné des plantes les plus intérressantes sous le rapport ornemental, comprenant leur histoire complete, leur description comparée, leur figure et leur culture /

v.6 (1859)

L'Illustration horticole : journal spécial des serres et des jardins, ou choix raisonné des plantes les plus intérressantes sous le rapport ornemental, comprenant leur histoire complete, leur description comparée, leur figure et leur culture /

v.7 (1860)

L'Illustration horticole : journal spécial des serres et des jardins, ou choix raisonné des plantes les plus intérressantes sous le rapport ornemental, comprenant leur histoire complete, leur description comparée, leur figure et leur culture /

v.8 (1861)

L'Illustration horticole : journal spécial des serres et des jardins, ou choix raisonné des plantes les plus intérressantes sous le rapport ornemental, comprenant leur histoire complete, leur description comparée, leur figure et leur culture /

v.9 (1862)

L'Illustration horticole : journal spécial des serres et des jardins, ou choix raisonné des plantes les plus intérressantes sous le rapport ornemental, comprenant leur histoire complete, leur description comparée, leur figure et leur culture /

v.10 (1863)

L'Illustration horticole : journal spécial des serres et des jardins, ou choix raisonné des plantes les plus intérressantes sous le rapport ornemental, comprenant leur histoire complete, leur description comparée, leur figure et leur culture /

v.11 (1864)