New Generation Antidepressants in Painful Diabetic Neuropathy

The incidence of diabetic neuropathy increases with the duration of diabetes and the degree of hyperglycaemia. Pain is one of the most common and incapacitating symptoms of diabetic neuropathy and its pharmacological control is complex. The effectiveness of antidepressive agents has been described in different types of neuropathic pain, but their effectiveness, when used as analgesics in painful diabetic neuropathy, still remains controversial. Objective: To review the possible role of new-generation antidepressive agents in the treatment of pain in diabetic peripheral neuropathy. This work has thus consisted of a meta-analysis for determining which antidepressive agent had the best analgesic potential in managing pain in patients suffering from painful diabetic neuropathy. Methods: This search covered the Cochrane, MEDLINE, EMBASE and LILACS databases, between January 2000 and August 2007. The following information was obtained from each article: criteria for diagnosing diabetic neuropathy, patients' age average, antidepressant drug received and dose, sample size, duration of the disease and treatment follow-up, outcome measurement, evaluation of pain and rescue medication. Results: A combined RR: 1.67 (95% CI 1.38 - 2.02) was obtained; this result indicated that the antidepressive agent duloxetine, was effective for controlling pain in diabetic neuropathy. The corresponding NNT for Duloxetine was established, according to our interests; NNT = 6 (95% CI 5- 8) for achieving greater than 50% analgesia in patients suffering from painful diabetic neuropathy. Discussion: Antidepressive agents are frequently employed in the specific case of diabetic neuropathy; their analgesic benefit has been demonstrated.

Methodology for measuring the impact of mobile technology change from 2nd to 3th generation percerved by users of smes in Barranquilla

This article presents the results of a research project undertaken to obtain a Masters inBusiness Administration from the Business School at the Universidad del Norte, whosepurpose was to identify and test a methodology to measure the impact exerted by thechange from 2nd to 3rd generation mobile tech, based on the perception of users belongingto Barranquilla SME, motivated by the influence of technological changes in behavior andthe knowledge creation among society members, and the importance it has taken to thesurvival of organizations the adoption of applications for process automation, web-basedapplications, voice, data and video that allow the development of competitive advantages,based on information and creativity for new and better products or services.

Modernisme : segona generació = Modernismo : segunda generación = Modernisme : the second generation = Le Modernisme : seconde génération.

Guía para la visita de las salas quince y diecisiete del Museo de Arte Moderno de Cataluña. Estas salas tratan contenidos sobre la segunda generación del Modernismo. Mediante un mapa, esta guía orienta al visitante por los distintos espacios de las salas.

Noucentisme : la generació del 1917 = Noucentisme : la generación de 1917 = Noucentisme : the generation of 1917 = Le Noucentisme : la génération de 1917.

Guía para la visita de la sala veinte del Museo de Arte Moderno de Cataluña. Esta sala trata contenidos sobre el movimento artístico catalán Noucentisme, en concreto, la llamada Generación de 1917. Mediante un mapa, esta guía orienta al visitante por los distintos espacios de la sala.

Text generation : writing 11 to 14. Book 1.

Recurso para ayudar a los estudiantes de primero de secundaria a mejorar el nivel en la escritura. Cubre todas las etapas del proceso de escritura y los objetivos señalados para la enseñanza del inglés e incluye, entre otros, la creación de personajes, la escritura de relatos cortos, la escritura de reseñas y el lenguaje del marketing.

Text generation : writing 11 to 14. Book 2.

Recurso para ayudar a los estudiantes de segundo de secundaria a aumentar el nivel en la escritura. Cubre todas las etapas del proceso de escritura y los objetivos señalados para la enseñanza del inglés e incluye, entre otros, el lenguaje figurado, la forma poética, narración de cuentos, información, descripción y análisis, la retórica persuasiva y la lógica persuasiva.

Text generation : writing 11 to 14. Book 3.

Recurso para ayudar a los estudiantes de secundaria a aumentar el nivel en la escritura. Cubre todas las etapas del proceso de escritura y los objetivos señalados para la enseñanza del inglés e incluye, entre otros, la narrativa, formas poéticas, literatura de viajes, argumento persuasivo, análisis literario y tipos de texto y parodia.

Are discourse comprehension and cognitive processes influenced by the type of language language (English and Spanish)? A cross-language study based on elaborative inferences generation

Resumen basado en el de la publicación

The effects of question-generation training on metacognitive knowledge, self regulation and learning approaches in Science

Resumen tomado de la publicaci??n

Automatic generation of active coordinates for quantum dynamics calculations: application to the dynamics of benzene photochemistry

A new practical method to generate a subspace of active coordinates for quantum dynamics calculations is presented. These reduced coordinates are obtained as the normal modes of an analytical quadratic representation of the energy difference between excited and ground states within the complete active space self-consistent field method. At the Franck-Condon point, the largest negative eigenvalues of this Hessian correspond to the photoactive modes: those that reduce the energy difference and lead to the conical intersection; eigenvalues close to 0 correspond to bath modes, while modes with large positive eigenvalues are photoinactive vibrations, which increase the energy difference. The efficacy of quantum dynamics run in the subspace of the photoactive modes is illustrated with the photochemistry of benzene, where theoretical simulations are designed to assist optimal control experiments

Le musee local de la nouvelle generation au Portugal, un pas en avant dans la gestion communautaire qualitative : essai d'interprétation épistémologique

Le musée local, au Portugal, tel qu’il apparaît dans la perspective de la révolution socio-cultureile de 74, puis projeté à l’avant-scène de la muséologie portugaise renaissante, lors du IIe Atelier international de Nouvelle muséologie (Lisbonne/Seixal/Monte Redondo — Musées locaux/Nouvelle musólogie, novembre 85), se perpétue jusqu’à nos jours, tout au moins dans le discours de ses promoteurs, préoccupé par le rapport aux pouvoirs et aux populations. Fortement enraciné dans la structure municipale et associative, utilisé à ses débuts, à des degrés divers, comme un outil de militance communautaire, le musée local présente un modèle muséographique de type ethnographique diffusé à travers le pays. Celui-ci est fondé sur la participation de donateurs d’objets utiles de la vie courante, mis à contribution dans le programme, de même que sur l’apport des savoir-faire populaires et artisanaux, évitant de tomber dans le folklorisme par une réflexion alimentée par les universitaires. Ce mouvement naissant correspond à la mode de l’écomusée dont il épouse certains contours, tout en demeurant enraciné dans la tradition ethnographique du pays.

An ontological approach to competency management

Competency management is a very important part of a well-functioning organisation. Unfortunately competency descriptions are not uniformly specified nor defined across borders: National, sectorial or organisational, leading to an opaque competency description market with a multitude of competency frameworks and competency benchmarks. An ontology is a formalised description of a domain, which enables automated reasoning engines to be built which by utilising the interrelations between entities can make “intelligent” choices in different situations within the domain. Introducing formalised competency ontologies automated tools, such as skill gap analysis, training suggestion generation, job search and recruitment, can be developed, which compare and contrast different competency descriptions on the semantic level. The major problem with defining a common formalised ontology for competencies is that there are so many viewpoints of competencies and competency frameworks. Work within the TRACE project has focused on finding common trends within different competency frameworks in order to allow an intermediate competency description to be made, which other frameworks can reference. This research has shown that competencies can be divided up into “knowledge”, “skills” and what we call “others”. An ontology has been created based on this with a simple structure of different “kinds” of “knowledges” and “skills” using semantic interrelations to define the basic semantic structure of the ontology. A prototype tool for analysing a skill gap analysis has been developed. Personal profiles can be produced using the tool and a skill gap analysis is performed on a desired competency profile by using an ontologically based inference engine, which is able to list closest fit and possible proficiency gaps