Modelo de canal para caracterizar la señal dispersada por un parque eólico en la banda UHF e influencia sobre la calidad de servicio de DVB-T

288 p. : il.

Mantenimiento en el laboratorio del pez cebra

El pez cebra (Danio rerio) se utiliza como organismo modelo en distintos campos como la biomedicina o la toxicogenómica. Las ventajas que ofrece frente a otros modelos animales, hace que se haya convertido en los últimos años en uno de los organismos modelo más utilizado en experimentación. La similitud de su desarrollo embrionario con el de otros vertebrados superiores o la semejanza de su genoma con la del ser humano lo han colocado en el punto de mira de las principales investigaciones. Pero disponer de ejemplares óptimos tanto de embriones como de adultos para su utilización en investigación, requiere de unos cuidados y de una atención adecuada. Para su mantenimiento se deberán tener en cuenta el tipo de instalaciones para su cría, la calidad del agua donde se encuentran, la alimentación que reciben o los procesos de reproducción utilizados. El objetivo de este estudio ha sido elaborar un protocolo de mantenimiento del pez cebra, que optimice los cuidados necesarios para que el número de embriones viables sea máximo y también poder mantener un número de ejemplares adultos en buenas condiciones.

O meio de se fazer pintor em tres horas :e de executar com o pincel as obras dos maiores mestres, sem se ter aprendido o desenho

Traduzido do francez.

Memória sobre a qualidade, e sobre o emprego dos adubos, ou estrumes

Traduzida de Ordem Superior.

O grande livro dos pintores, ou, arte da pintura : considerada em todas as suas partes, e demonstrada por princípios, com reflexões sober as obras d'alguns bons mestres, e sobre as faltas que nelles se encontraõ

Por Gerardo Lairesse ; traducção do francez de Ordem, e debaixo dos auspícios de Sua Alteza Real O Principe Regente N. S.

Princípios da arte da gravura : trasladados do grande livro dos pintores de Gerardo Lairesse, livro decimoterceiro para servirem de appendice aos principios do desenho do mesmo author, em beneficio dos gravadores do Arco do Cego

A obra é parte do esforço de produção de livros didáticos empreendidos por Frei Velloso.

Programación Lineal Posibilística

Estudiamos un programa general de programación lineal posibilista en el que todos los parametros pueden ser fuzzy, así como las restricciones. Obtenemos la distribución de posibilidad de la solución en función del grado de cumplimiento de las restricciones. Con esta información se le plantea al decisor que especifique una meta para su objetivo, y estudiamos como alcanzar dicha meta con un nivel satisfactorio sopesándolo con el grado de cumplimiento de las restricciones.

Matemáticas, realidad y ciencia económica

Debido a la juventud de las ciencias económicas la discusión sobre la forma de utilizar las matemáticas en ellas permanece todavía abierta. En este artículo se tratara de responder a las cuestiones del "por qué" y, a la sin duda más actual, del "cómo" de la utilización de las matemáticas superiores en la economía.

Osakidetzako erietxe bateko jardueraren eta aurrekontu zuzkiduraren egokitzapena

Idazleen nahia, esatariaren lehentasunak eta antolaketa mugaketak kontuan izanik, helburu anitzeko eredu bat zehaztea da, horrela Osakidetzako erietxe konkretu bateko jarduera zehaztu ahal izango dugu eta beraz, baita aurrekontuaren esleipena. Aldi berean, aurrekontu zuzkidura doituz, zentroaren baliabideen erabilpenaren efizientzia azter dezakegu eta orokorrean, zentroaren osasun-laguntzen emaitzak hobetzen lagundu dezakete.

Description of Early Larvae of Four Northern California Species of Rockfishes (Scorpaenidae: Sebastes) from Rearing Studies

About 72 species of Sebastes (Family Scorpaenidae) are found along the eastern Pacific coast of North America, some of which are heavily exploited by both commercial and sport fisheries. Because of the large number of species, the identification of early life stages has progressed slowly. The objectives of this study were 1) to rear the larvae of four species of rockfish (Sebastes mystinus, S. carnatus, S. atrovirens, and S. rastrelliger); and 2) to describe the larvae using morphometric measurements, pigmentation patterns, and head spination. Pigmentation was the most useful feature for identification purposes. Two general patterns were found: 1) a short row of ventral midline melanophores on the tail, and none or very little postero-dorsal pigmentation (S. mystinus); and 2) complete ventral midline pigmentation on the tail, and anterior and postero-dorsal melanophores (S. carnatus, S. atrovirens, and S. rastrelliger). With the exception of very early stages of S. carnatus and S. atrovirens, these species can be readily identified. Morphometric proportions and head spination did not show major differences among species. Because of the great similarities found among species in this genus, descriptions from field studies are uncertain to some extent. Laboratory rearings, although difficult, can at least provide early larvae from known species which allow precise identification as well as an estimation ofvariability of characters (e.g., pigmentation) within and between broods.(PDF file contains 22 pages.)

Elementos de geometria / por A. M. Legendre ; traduzidos do francez, e dedicados ao Principe Regente Nosso Senhor por Manoel Ferreira de Araujo Guimarães

Bibliografia da Impressão Régis informa que "Publicada pela primeira vez em Paris em 1794, a obra logo se tornou clássica. A edição do Rio de Janeiro, destinada aos alunos da Academia Militar, apresenta treze estampas com figuras geométricas , as primeiras a serem gravadas na Impressão Régia; não trazem assinatura, porém devem ter sido feiras por Romão Elói de Almeida ou por Paulo dos Santos Ferreira Souto, artistas da Tipografia do Arco do Cego, de Lisboa, recém-chegados ao Brasil por Frei José Mariano da Conceição Velloso..." Texto escurecidos pela acidez com marcas de cupim.

GABAergic and Cortical and Subcortical Glutamatergic Axon Terminals Contain CB1 Cannabinoid Receptors in the Ventromedial Nucleus of the Hypothalamus

Background: Type-1 cannabinoid receptors (CB1R) are enriched in the hypothalamus, particularly in the ventromedial hypothalamic nucleus (VMH) that participates in homeostatic and behavioral functions including food intake. Although CB1R activation modulates excitatory and inhibitory synaptic transmission in the brain, CB1R contribution to the molecular architecture of the excitatory and inhibitory synaptic terminals in the VMH is not known. Therefore, the aim of this study was to investigate the precise subcellular distribution of CB1R in the VMH to better understand the modulation exerted by the endocannabinoid system on the complex brain circuitries converging into this nucleus. Methodology/Principal Findings: Light and electron microscopy techniques were used to analyze CB1R distribution in the VMH of CB1R-WT, CB1R-KO and conditional mutant mice bearing a selective deletion of CB1R in cortical glutamatergic (Glu-CB1R-KO) or GABAergic neurons (GABA-CB1R-KO). At light microscopy, CB1R immunolabeling was observed in the VMH of CB1R-WT and Glu-CB1R-KO animals, being remarkably reduced in GABA-CB1R-KO mice. In the electron microscope, CB1R appeared in membranes of both glutamatergic and GABAergic terminals/preterminals. There was no significant difference in the percentage of CB1R immunopositive profiles and CB1R density in terminals making asymmetric or symmetric synapses in CB1R-WT mice. Furthermore, the proportion of CB1R immunopositive terminals/preterminals in CB1R-WT and Glu-CB1R-KO mice was reduced in GABA-CB1R-KO mutants. CB1R density was similar in all animal conditions. Finally, the percentage of CB1R labeled boutons making asymmetric synapses slightly decreased in Glu-CB1R-KO mutants relative to CB1R-WT mice, indicating that CB1R was distributed in cortical and subcortical excitatory synaptic terminals. Conclusions/Significance: Our anatomical results support the idea that the VMH is a relevant hub candidate in the endocannabinoid-mediated modulation of the excitatory and inhibitory neurotransmission of cortical and subcortical pathways regulating essential hypothalamic functions for the individual's survival such as the feeding behavior.

Mitigation Techniques to Reduce the Impact of Wind Turbines on Radar Services

Radar services are occasionally affected by wind farms. This paper presents a comprehensive description of the effects that a wind farm may cause on the different radar services, and it compiles a review of the recent research results regarding the mitigation techniques to minimize this impact. Mitigation techniques to be applied at the wind farm and on the radar systems are described. The development of thorough impact studies before the wind farm is installed is presented as the best way to analyze in advance the potential for interference, and subsequently identify the possible solutions to allow the coexistence of wind farms and radar services.

A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12

Background: Colorectal cancer (CRC) is a disease of complex aetiology, with much of the expected inherited risk being due to several common low risk variants. Genome-Wide Association Studies (GWAS) have identified 20 CRC risk variants. Nevertheless, these have only been able to explain part of the missing heritability. Moreover, these signals have only been inspected in populations of Northern European origin. Results: Thus, we followed the same approach in a Spanish cohort of 881 cases and 667 controls. Sixty-four variants at 24 loci were found to be associated with CRC at p-values <10-5. We therefore evaluated the 24 loci in another Spanish replication cohort (1481 cases and 1850 controls). Two of these SNPs, rs12080929 at 1p33 (P-replication=0.042; P-pooled=5.523x10(-03); OR (CI95%)=0.866(0.782-0.959)) and rs11987193 at 8p12 (P-replication=0.039; P-pooled=6.985x10(-5); OR (CI95%)=0.786(0.705-0.878)) were replicated in the second Phase, although they did not reach genome-wide statistical significance. Conclusions: We have performed the first CRC GWAS in a Southern European population and by these means we were able to identify two new susceptibility variants at 1p33 and 8p12 loci. These two SNPs are located near the SLC5A9 and DUSP4 loci, respectively, which could be good functional candidates for the association signals. We therefore believe that these two markers constitute good candidates for CRC susceptibility loci and should be further evaluated in other larger datasets. Moreover, we highlight that were these two SNPs true susceptibility variants, they would constitute a decrease in the CRC missing heritability fraction.

SU-8 microprobes for biomedical applications

152 p. : il.