992 resultados para Inter-modality re-weighting


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O aumento da biomassa vegetal subterrânea e da estabilidade dos agregados do solo pelo seu manejo adequado aumentam sua capacidade para infiltrar água da chuva e resistir à erosão hídrica. Baseado nesta premissa, foi realizado um estudo de erosão em campo, sob chuva simulada, na Estação Experimental Agronômica da Universidade Federal do Rio Grande do Sul - EEA/UFRGS, em Eldorado do Sul (RS), no verão de 2003/2004, utilizando um experimento de manejo do solo com 7,5 anos de duração. O objetivo da pesquisa foi investigar relações entre variáveis de manejo e de erosão, relacionadas à história de uso e manejo do solo e suas condições físicas superficiais momentâneas, criadas por tratamentos de seu preparo e de cobertura por resíduo cultural, os quais foram aplicados imediatamente antes da realização de testes de erosão com chuva simulada. Utilizou-se um Argissolo Vermelho distrófico típico, com textura superficial franco-argilo-arenosa e declividade média de 0,115 m m-1. Foram estudadas quatro seqüências culturais, com ou sem preparo (gradagem) e cobertura (resíduo cultural) do solo. Realizaram-se três testes de erosão com chuva simulada, cada um na intensidade de 64 mm h-1 e duração de 1,5 h, usando o aparelho simulador de braços rotativos. Avaliaram-se a massa de raízes mortas das plantas, o diâmetro médio ponderado de agregados do solo, a taxa constante de infiltração de água no solo e a perda total de água e de solo por erosão. A infiltração de água no solo foi maior e, inversamente, a perda de água menor no solo recém-mobilizado (superfície solta e rugosa) do que no solo não-mobilizado (superfície firme e praticamente lisa), mesmo o primeiro estando descoberto e o segundo tanto coberto quanto descoberto, com diferenças entre as seqüências culturais. No solo não-mobilizado e coberto, a perda foi pequena em todas as seqüências culturais, enquanto no solo descoberto, tanto não-mobilizado quanto recém-mobilizado, ela foi pequena somente naquelas seqüências culturais que propiciaram altos valores de massa de raízes mortas das plantas e de diâmetro médio ponderado de agregados do solo. No solo recém-mobilizado e descoberto, a diminuição da perda de solo também se deveu à rugosidade superficial criada pelo preparo. As relações da perda total de água e da perda total de solo, com a massa de raízes mortas das plantas e com o diâmetro médio ponderado de agregados do solo, foram significativas a 5 %.

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The objective of this paper is to explore the relative importance of each of Marshall's agglomeration mechanisms by examining the location of new manufacturing firms in Spain. In particular, we estimate the count of new firms by industry and location as a function of (pre-determined) local employment levels in industries that: 1) use similar workers (labor market pooling); 2) have a customer- supplier relationship (input sharing); and 3) use similar technologies (knowledge spillovers). We examine the variation in the creation of new firms across cities and across municipalities within large cities to shed light on the geographical scope of each of the three agglomeration mechanisms. We find evidence of all three agglomeration mechanisms, although their incidence differs depending on the geographical scale of the analysis.

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BACKGROUND: Dysregulation of voltage-gated sodium channels (Na(v)s) is believed to play a major role in nerve fiber hyperexcitability associated with neuropathic pain. A complete transcriptional characterization of the different isoforms of Na(v)s under normal and pathological conditions had never been performed on mice, despite their widespread use in pain research. Na(v)s mRNA levels in mouse dorsal root ganglia (DRG) were studied in the spared nerve injury (SNI) and spinal nerve ligation (SNL) models of neuropathic pain. In the SNI model, injured and non-injured neurons were intermingled in lumbar DRG, which were pooled to increase the tissue available for experiments. RESULTS: A strong downregulation was observed for every Na(v)s isoform expressed except for Na(v)1.2; even Na(v)1.3, known to be upregulated in rat neuropathic pain models, was lower in the SNI mouse model. This suggests differences between these two species. In the SNL model, where the cell bodies of injured and non-injured fibers are anatomically separated between different DRG, most Na(v)s were observed to be downregulated in the L5 DRG receiving axotomized fibers. Transcription was then investigated independently in the L3, L4 and L5 DRG in the SNI model, and an important downregulation of many Na(v)s isoforms was observed in the L3 DRG, suggesting the presence of numerous injured neurons there after SNI. Consequently, the proportion of axotomized neurons in the L3, L4 and L5 DRG after SNI was characterized by studying the expression of activating transcription factor 3 (ATF3). Using this marker of nerve injury confirmed that most injured fibers find their cell bodies in the L3 and L4 DRG after SNI in C57BL/6 J mice; this contrasts with their L4 and L5 DRG localization in rats. The spared sural nerve, through which pain hypersensitivity is measured in behavioral studies, mostly projects into the L4 and L5 DRG. CONCLUSIONS: The complex regulation of Na(v)s, together with the anatomical rostral shift of the DRG harboring injured fibers in C57BL/6 J mice, emphasize that caution is necessary and preliminary anatomical experiments should be carried out for gene and protein expression studies after SNI in mouse strains.

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Isolated ventricular non-compaction (IVNC) is a rare, congenital, unclassified cardiomyopathy characterized by prominent trabecular meshwork and deep recesses. Major clinical manifestations of IVNC are heart failure, atrial and ventricular arrhythmias, and thrombo-embolic events. We describe a case of a 69-year-old woman in whom the diagnosis of IVNC was discovered late, whereas former echocardiographic examinations were considered normal. She was known for systolic left ventricular dysfunction for 3 years and then became symptomatic (NYHA III). In the past, she suffered from multiple episodes of deep vein thrombosis and pulmonary embolism. Electrocardiogram revealed a wide QRS complex, and transthoracic echocardiography showed typical apical thickening of the left and right ventricular myocardial wall with two distinct layers. The ratio of non-compacted to compacted myocardium was >2:1. Cardiac MRI confirmed the echocardiographic images. Cerebral MRI revealed multiple ischaemic sequellae. In view of the persistent refractory, heart failure in medical treatment of patients with classical criteria for cardiac re-synchronization therapy, as well as the ventricular arrhythmias, a biventricular automatic intracardiac defibrillator (biventricular ICD) was implanted. The 2-year follow-up period was characterized by improvement of NYHA functional class from III to I and increasing in left ventricular function. We hereby present a case of IVNC with favourable outcome after biventricular ICD implantation. Cardiac re-synchronization therapy could be considered in the management of this pathology.

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The objective of this paper is to explore the relative importance of each of Marshall's agglomeration mechanisms by examining the location of new manufacturing firms in Spain. In particular, we estimate the count of new firms by industry and location as a function of (pre-determined) local employment levels in industries that: 1) use similar workers (labor market pooling); 2) have a customer- supplier relationship (input sharing); and 3) use similar technologies (knowledge spillovers). We examine the variation in the creation of new firms across cities and across municipalities within large cities to shed light on the geographical scope of each of the three agglomeration mechanisms. We find evidence of all three agglomeration mechanisms, although their incidence differs depending on the geographical scale of the analysis.

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[cat] Analitzem una economia amb dues característiques principals: la mobilitat dels treballadors implica transferència de coneixement i la productivitat de l’empresa augmenta amb l’intercanvi de coneixement. Cada empresa desenvolupa un tipus de coneixement que serà trasmès a la resta de la indústria mitjançant la mobilitat de treballadors. Estudiem dues estructures de mercat laboral i utilitzant un anàlisi comparatiu derivem les implicacions del model. Els resultats revelen com la mobilitat de treballadors depèn en la varietat i nivell del coneixement, la presència de costos de mobilitat, les institucions, la capacitat d’absorvir coneixement per part de les empreses i la mida de la indústria. Els resultats no depenen de l’estructura del mercat laboral.

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Diffusion MRI is a well established imaging modality providing a powerful way to non-invasively probe the structure of the white matter. Despite the potential of the technique, the intrinsic long scan times of these sequences have hampered their use in clinical practice. For this reason, a wide variety of methods have been proposed to shorten acquisition times. [...] We here review a recent work where we propose to further exploit the versatility of compressed sensing and convex optimization with the aim to characterize the fiber orientation distribution sparsity more optimally. We re-formulate the spherical deconvolution problem as a constrained l0 minimization.