Una pecadora : drama en cinco actos, arreglado a la escena española /

"Se vende en Madrid en la librería de Cuesta, calle de Carretas " -cub.-

Leçons de phrénologie scientifique et pratique... /

Precede al tít.: La phrénologie régénéré du veritable système de philosophie de l'homme considéré dans tous ses rapports.

A description of the Royal Colosseum : re-opened M.DCCC.XLV., under the patronage of Her Majesty the Queen & His Royal Highness Prince Albert : re-embellished in 1851

Fecha tomada de cub.

Memorial de su Magestad [sic] católica el Señor D. Felipe IV, presentado a la Santidad del Papa Urbano VIII en la embajada a que fueron a Roma en el año de 1633 D. Fray Domingo Pimentel, Obispo de Córdoba y D. Juan Chumacero y Carrillo... ; Respuesta dada de orden de Su Santidad por Monseñor Miraldi, Secretario de Breves ; y replica de los señores Pimentel y Chumacero...

Tít. de la cub.: Memorial del Rey Don Felipe IV, presentado al Papa Urbano VIII.

Salluste, Jules César, C. Velléius Paterculus et A. Florus : oeuvres complètes /

Contiene: Salluste, P. 3-159 ; Jules César, P. [161]-531 ; C. Velléius Parteculus, P. [533]-617 ; L. Aneus Florus, p. [619]-727, todas con portadilla propia.

Sistema completo de frenología, con sus aplicaciones al adelanto i mejoramiento del hombre, individual i sozialmente considerado.

Mode of access: Internet.

Viaje de Anacarsis a la Grecia /

Tit. de la cub.: Viaje de Anacarsis.

Estractos de los mas celebres escritores españoles : en prosa y verso para el uso del Colegio de Sta. Maria.

Front and back cover missing.

Gramática de la lengua castellana.

Mode of access: Internet.

Handbooks for boys.

Vols. for published as Every boy's library, Boy scout ed.

Real soldiers of fortune /

Major-General Henry Ronald Douglas Maclver.--Baron James Harden-Hickey.--Winston Spencer Churchill.--Captain Philo Norton McGriffin.--General William Walker, the king of the filibusters.--Major Burnham, chief of scouts.

Marjorie Merriweather Post receiving Boy Scout award

On verso: Photography by George Kalec Washington, D.C.

The Official handbook for boys.

Mode of access: Internet.

Real soldiers of fortune,

Major-General Henry Ronald Douglas MacIver.--Baron James Harden-Hickey.--Winston Spencer Churchill.--Captain Philo Norton McGiffin.--General William Walker, the king of the filibusters.--Major Burnham, chief of scouts.

Scube2 mediates Hedgehog signalling in the zebrafish embryo

The Hedgehog family of secreted morphogens specifies the fate of a large number of different cell types within invertebrate and vertebrate embryos, including the muscle cell precursors of the embryonic myotome of zebrafish. Formation of Hedgehog-sensitive muscle fates is disrupted within homozygous zebrafish mutants of the you-type class, the majority of which disrupt components of the Hedgehog (HH) signal transduction pathway. We have undertaken a phenotypic and molecular characterisation of one of these mutants, you, which we show results from mutations within the zebrafish orthologue of the mammalian, gene scube2. This gene encodes a member of the Scube family of proteins, which is characterised by several protein motifs including EGF and CUB domains. Epistatic and molecular analyses position Scube2 function upstream of Smoothened (Smoh), the signalling component of the HH receptor complex, suggesting that Scube2 may act during HH signal transduction prior to, or during, receipt of the HH signal at the plasma membrane. In support of this model we show that scube2 has homology to cubilin, which encodes an endocytic receptor involved in protein trafficking suggesting a possible mode of function for Scube2 during HH signal transduction. (c) 2006 Elsevier Inc. All rights reserved.