Impact of the length of vitamin D deficiency on cardiac remodeling.

This study was aimed to evaluate the influence of vitamin D (VD) deficiency on cardiac metabolism, morphology, and function. Thus, we investigated the relationship of these changes with the length of the nutrient restriction. Male weanling Wistar rats were allocated into 4 groups: C2 (n=24), animals were fed an AIN-93G diet with 1000 IU VD/kg of chow and were kept under fluorescent light for 2 months; D2 (n=22), animals were fed a VD-deficient AIN-93G diet and were kept under incandescent light for 2 months; C4 (n=21) animals were kept in the same conditions of C2 for 4 months; and D4 (n=23) animals were kept in the same conditions of D2 for 4 months. Biochemical analyses showed lower β-hydroxyacyl coenzyme-A dehydrogenase activity and higher lactate dehydrogenase activity in VD-deficient animals. Furthermore, VD deficiency was related to increased cytokines release, oxidative stress, apoptosis, and fibrosis. Echocardiographic data showed left ventricular hypertrophy and lower fractional shortening and ejection fraction in VD-deficient animals. Difference became evident in the lactate dehydrogenase activity, left ventricular weight, right ventricle weight, and left ventricular mass after 4 months of VD deficiency. Our data indicate that VD deficiency is associated with energetic metabolic changes, cardiac inflammation, oxidative stress, fibrosis and apoptosis, cardiac hypertrophy, left chambers alterations, and systolic dysfunction. Furthermore, length of the restriction influenced these cardiac changes.

Ultrassonografia oftálmica em cães com diferentes conformações cranianas

The aim of this study was to establish mean values for intraocular structures and analyse if the differences are present for different skull conformations in dogs. In this study, 30 dogs were selected and distributed into three groups according to skull conformation; thus, group 1 (G1) was composed of brachycephalic dogs, group 2 (G2) was composed of mesocephalic dogs and group 3 (G3) was composed of dolichocephalic dogs. A and B-mode ultrasound was performed simultaneously for obtainment of measurements relating to anterior chamber depth (D1); lens thickness (D2); vitreous chamber depth (D3); and the axial length of the eye (D4). No differences were observed when comparing left and right eyes of dogs within the same skull conformation group (p>0.05). Differences were observed when comparing D3 and D4 between groups G2 and G3 (p<0.05). Skull conformation of brachycephalic dogs did not influence intraocular measurement values when compared to dolicephalic and mesocephalic dogs. Skull conformation of dolichocephalic dogs had an influence in values of vitreous chamber and the complete length of the eye when compared to mesocephalic dogs.

On singular foliations on the solid torus

We study smooth foliations on the solid torus S1×D2 having S1×{0} and S1×∂D2 as the only compact leaves and S1×{0} as singular set. We show that all other leaves can only be cylinders or planes, and give necessary conditions for the foliation to be a suspension of a diffeomorphism of the disc. © 2013 Elsevier B.V.

Stocking density of Nile tilapia in cages placed in a hydroelectric reservoir

The Brazilian government has been encouraging fish farming in cages in federal water bodies, including hydroelectric reservoirs. Despite the government support, it is a new activity and the production model still needs some adjustment to reduce the production costs and achieve sustainability. The aims of this study were to determine the appropriate stocking density of Nile tilapia in cages in a hydroelectric reservoir and to evaluate to what extent fish size selection could improve their uniformity. Twelve cages (6m3) were placed at the Fish Farmers' Cooperative of Santa Fé do Sul and Region, Ilha Solteira reservoir, São Paulo, Brazil (20°12'10″S, 50°58'31.15″W). In stage I (initial fish weight, 78g), four stocking densities were tested: D1-800, D2-2000, D3-2500 and D4-3000 fish/cage, with three replicates. At the end of this stage (average fish weight, 255g), the fish were selected into three sizes, except for D1. In stage II, four stocking densities were tested, designed to obtain the following final production: D1-100kg/m3 (800 non-selected fish/cage), D2-80kg/m3 (600 fish/cage), D3-100kg/m3 (800 fish/cage) and D4-120kg/m3 (900 fish/cage). The trial ended when the fish weighed 800g. By reducing the initial stocking density from 2500 to 800 tilapia juveniles per cage, there was no need for selection. The growth performance was higher, the feed conversion rate was better and the time taken to reach harvesting was shorter. Consequently, the production cost reduced and the operating profit increased. Using the lowest initial stocking density, the risk of disease outbreak was also lower, and there was no need to use drugs for disease control since the mortality rate and occurrences of disease and deformity decreased and the dissolved oxygen level inside the cages was higher. © 2013 Elsevier B.V.

A expressão da estrutura argumental dos nomes derivados

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Isolamento de leveduras fermentadoras de pentoses e suas aplicações na produção de xilitol e etanol a partir do licor negro proveniente do processo Kraft de extração da celulose

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Remodelação cardíaca induzida plea deficiência de vitamina D em ratos. -

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Desempenho de métodos baseados na indução de fluorescência para a detecção de lesões de cárie em superfícies oclusais e proximais: estudos in vitro

Pós-graduação em Ciências Odontológicas - FOAR

Ultrassonografia do bulbo do olho de cães, com diferentes conformações cranianas

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Avaliação da atividade apoptótica de substância pura isolada de Cryptocarya mandioccanna em células de carcinoma cervical imortalizadas pelo papilomavirus humano (HPV)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Análise econômica da aplicação de biossólido na agricultura

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Caracterização estrutural de um segmento da rampa lateral de capitólio, limite norte da Nappe de Passos - MG

Pós-graduação em Geologia Regional - IGCE

Participação das vias alfa 2 - adrenérgica, dopaminérgica e gabaérgica no controle da secreção de GH no período pré-púbere de novilhas da raça nelore

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Isolamento e caracterização de leveduras de Polybia ignobilis (Hymenoptera: Vespidae)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Leveduras isoladas de ninhos de formigas da tribo Attini (Hymeniptera: Formicidae)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)