Why we must empower people to conserve Biodiversity

Conserving blodiversity has in recent years become a concern of the global elite because of the commercial potential of the emerging biotechnologies. But much of this blodiversity resides In the Third World tropics which are currently being drained of their biological and mineral wealth. This process goes on because the costs of the resultant degradation are entirely passed on to the poor of the Third World countryside who perforce have to depend on resources gathered or produced with their own labour from their surroundings. The elite have always found a substitute whenever a particular resource, or a particular locality, has been exploited to exhaustion. Indeed, given their record, commercial interests are likely to abandon the new found concern for conservation once they acquire control over adequate levels of genetic resources in ex situ storages. Long term conservation of biodiversity must therefore be attempted through empowering and suitably rewarding people of the Third World countryside whose well being is linked to the sustainable use of biological resources and conservation of the biodiversity in their own localities.

HLA-B*57 and Gender Influence the Occurrence of Tuberculosis in HIV Infected People of South India

Background. Substantial evidence exists for HLA and other host genetic factors being determinants of susceptibility or resistance to infectious diseases. However, very little information is available on the role of host genetic factors in HIV-TB coinfection. Hence, a longitudinal study was undertaken to investigate HLA associations in a cohort of HIV seropositive individuals with and without TB in Bangalore, South India. Methods. A cohort of 238 HIV seropositive subjects were typed for HLA-A, B, and DR by PCR-SSP and followed up for 5 years or till manifestation of Tuberculosis. HLA data of 682 HIV Negative healthy renal donors was used as control. Results. The ratio of males and females in HIV cohort was comparable (50.4% and 49.6%). But the incidence of TB was markedly lower in females (12.6%,) than males (25.6%). Further, HLA-B* 57 frequency in HIV cohort was significantly higher among females without TB (21.6%, 19/88) than males (1.7%, 1/59); P = 0.0046; OR = 38. CD4 counts also were higher among females in this cohort. Conclusion. This study suggests that HIV positive women with HLA-B* 57 have less occurrence of TB as compared to males.

Simulating grasping behavior of people using the relational description scheme

This paper presents an enhanced relational description for the prescription of the grasp requirement and evolution of the posture of a digital human hand towards satisfaction of this requirement. Precise relational description needs anatomical segmentation of the hand geometry into palmar, dorsal and lateral patches using the palm-plane and joint locations information, and operational segmentation of the object geometry into pull,push and lateral patches with due consideration to the effect of friction. Relational description identifies appropriate patches for a desired grasp condition. Satisfaction of this requirement occurs in two discrete stages,namely,contact establishment and post-contact force exertion for object capturing. Contact establishment occurs in four potentially overlapping phases,namely,re-orientation,transfer,pre- shaping,and closing-in. The novel h and re-orientation phase,enables the palm to face the object in a task sequence scenario, transfer takes the wrist to the ball park ; pre-shaping and close-in finally achieves the contact. In this paper, an anatomically pertinent closed-form formulation is presented for the closing-in phase for identification of the point of contact on the patches ,prescribed by the relational description. Since mere contact does not ensure grasp and slip phenomenon at the point of contact on application of force is a common occurrence, the effect of slip in presence of friction has been studied for 2D and 3D object grasping endeavours and a computational generation of the slip locus is presented.A general slip locus is found to be a non-linear curve even on planar faces.Two varieties of slip phenomena,namely,stabilizing and non-stabilizing slips, and their local characteristics have been identified.Study of the evolution of this slip characteristic over the slip locus exhibited diverse grasping behaviour possibilities. Thus, the relational description paradigm not only makes the requirement specification easy and meaningful but also enables high fidelity hand object interaction studies possible.

A comparative phase 1 clinical trial to identify anti-infective mechanisms of vitamin D in people with HIV infection

Objectives:To determine if there is a biological mechanism that explains the association between HIV disease progression and increased mortality with low circulating vitamin D levels; specifically, to determine if restoring vitamin D levels induced T-cell functional changes important for antiviral immunity.Design:This was a pilot, open-label, three-arm prospective phase 1 study.Methods:We recruited 28 patients with low plasma vitamin D (<50nmol/l 25-hydroxyvitamin D3), comprising 17 HIV+ patients (11 on HAART, six treatment-naive) and 11 healthy controls, who received a single dose of 200000IU oral cholecalciferol. Advanced T-cell flow cytometry methods measured CD4(+) T-cell function associated with viral control in blood samples at baseline and 1-month after vitamin D supplementation.Results:One month of vitamin D supplementation restored plasma levels to sufficiency (>75nmol/l) in 27 of 28 patients, with no safety issues. The most striking change was in HIV+ HAART+ patients, where increased frequencies of antigen-specific T cells expressing macrophage inflammatory protein (MIP)-1 - an important anti-HIV blocking chemokine - were observed, with a concomitant increase in plasma MIP-1, both of which correlated significantly with vitamin D levels. In addition, plasma cathelicidin - a vitamin D response gene with broad antimicrobial activity - was enhanced.Conclusion:Vitamin D supplementation modulates disease-relevant T-cell functions in HIV-infected patients, and may represent a useful adjunct to HAART therapy. Copyright (C) 2015 Wolters Kluwer Health, Inc. All rights reserved.

The open parliament in the age of the internet : can the people now collaborate with legislatures in lawmaking?

This work seeks to address those questions and evaluate other international experiences and experiments designed to achieve the same ends. The book is based on a study of two particular cases where parliamentary bodies designed and implemented participatory digital processes, namely, the e-Democracy Program developed by the Brazilian House of Representatives, and the Virtual Senator Program developed by the Chilean Senate. The text unfolds in the form of a systematic analysis of institutional aspects embracing political and organizational elements as well as the social aspects associated to the application of digital democracy in parliaments. The investigation shows that at the stage they found themselves in 2010 those projects had only brought in very incipient results in regard to the aspects of enhancing representativity in decision making processes, aggregating collective intelligence to the legislative process or transparency to parliamentary performances, even though all of those are precious components of any democracy that deems itself to be participatory and deliberative. Nevertheless, such experiences have had the merit of contributing towards the gradual construction of more effective participatory mechanisms, complementary to the political representation system in place.

Annual report 2002 - North Pacific Marine Science Organization (PICES). Eleventh meeting, Qingdao, People's Republic of China, October 18-16, 2002

Report of Opening Session (pdf 51 KB) Report of Governing Council Meeting(pdf 136 KB) Report of the Finance and Administration Committee (pdf 48 KB) Reports of Science Board and Committees: Science Board (pdf 71 KB) Biological Oceanography Committee (pdf 66 KB) Working Group 14: Effective sampling of micronekton Marine Birds and Mammals Advisory Panel Fishery Science Committee (pdf 36 KB) Working Group 16: Climate change, shifts to fish production, and fisheries management Marine Environmental Quality Committee (pdf 39 KB) Working Group 15: Ecology of Harmful Algal Blooms (HABs) in the North Pacific Physical Oceanography and Climate Committee (pdf 49 KB) North Pacific Data Buoy Advisory Panel Working Group 17: Biogeochemical data integration and synthesis Technical Committee on Data Exchange (pdf 29 KB) Implementation Panel on the CCCC Program (pdf 43 KB) BASS Task Team (pdf 30 KB) Iron Fertilization Experiment Advisory Panel MODEL Task Team (pdf 28 KB) MONITOR Task Team (pdf 34 KB) Summary of Continuous Plankton Recorder activities in 2002 REX Task Team (pdf 21 KB) Documenting Scientific Sessions (pdf 140 KB) List of Participants (pdf 59 KB) List of Acronyms (pdf 21 KB)

Annual report 1995 - North Pacific Marine Science Organization (PICES). Fourth meeting, Qingdao, People's Republic of China, October 16-24, 1995

Report of Opening Session Report of Governing Council Meetings Reports of Science Board and Committees: Science Board Biological Oceanography Committee Fishery Science Committee Marine Environmental Quality Committee Physical Oceanography and Climate Committee Technological Committee on Data Exchange Finance and Administration: Report of the Finance and Administration Committee Assets on 31st of December, 1994 Income and Expenditures for 1994 Budget for 1996 Composition of the Organization List of Participants List of Acronyms (Document has 96 pages.)

Shell midden people in northern Iberia. New data from the mesolithic rock shelter of J3 (Basque Country, Spain)

[EN]In the course of a sondage dug in the rock shelter of J3, in the Jaizkibel mountains (at the north-western tip of Guipúzcoa), the body of a adult man was located buried inside a shell midden. This shell midden had not been disturbed and presented internal stratigraphy features. In any case, the outer edge of the shell midden does show some interesting interdigitation with the adjacent habitational layers, with evidence of different stages of occupation. Within the shell midden itself, under the individual buried there, it was possible to observe layers without any ceramics, whereas the layers covering said individual included ceramic fragments. This individual has been dated to 8,300 BP and therefore corresponds to a Mesolithic context.

The Rain Forests of Home: an Atlas of People and Place

pdf contains 31 pages