Papel da eritropoetina recombinante humana sobre o metabolismo dos carboidratos, paratormônio, cálcio iônico, zinco, prolactina e níveis pressóricos em renais crônicos tratados com hemodiálise

Objective: To evaluate the influence of recombinant human erythropoietin (Epho) on carbohydrate metabolism, parathyroid hormone, calcium ionic, zinc, prolactin and blood pressure (BP) in chronic renal failure treated by hemodialysis. Methods: Ten patients in hemodialysis were followed during 24 weeks in two phases: 12 weeks pre-Epho (BP was measured pre and post hemodialysis sessions) and 12 weeks post-Epho (BP was measured as above and also the blood levels of glucose, insulin, parathyroid hormone, calcium ionic, prolactin, and zinc). Results: Patients were 39.8±8.5 y, 50% males. Hematocrit and hemoglobin presented a significant increase four weeks after Epho (22.3±2.3 to 28.1±2.6% and 7.4±0.8 to 9.4±0.9 g/dL, p<0.05). BP (mmHg) and weight pre-Epho: 158±99 and 59±13 (before hemodialysis), 147±96 and 55±13 (after hemo) and post-Epho: 161±100 and 59±13 (before hemo) 155±101 and 56±12 (after hemo) were all not statistically different in any moment. There are also no difference pre and post-Epho in fast glucose (91.8±6.5 and 90.8±6.1 mg/dL, p>0.05), parathyroid hormone (341.4±249.3 and 515.7±310 pg/ mL), calcium ionic (3,66±0.63 and 3.76±0.45 mmol/L), prolactin (males: 327±144.1 and 298.1 ±145.2 μg/mL; females: 666.2±426.6 and 659±395.3 μg/mL) and zinc (median of 0.73 and 0.71 μg\L). Basal insulin was lower after Epho (median of 9.1 to 3.8 μg/mL, p<0.05). Conclusion: These data suggest that recombinant human erythropoietin was effective to improve the anemia and the carbohydrate metabolism in patients with chronic renal failure treated by hemodialysis. © Copyright Moreira Jr. Editors. Todos os direitos reservados.

Construction of ethics in clinical research - Clinical trials registration

Scientific development that has been achieved through decades finds in clinical research a great possibility of translating findings to human health application. Evidence given by clinical trials allows everyone to have access to the best health services. However, the millionaire world of pharmaceutical industries has stained clinical research with doubt and improbability. Study results (fruits of controlled clinical trials) and scientific publications (selective, manipulated and with wrong conclusions) led to an inappropriate clinical practice, favoring the involved economic aspect. In 2005, the International Committee of Medical Journal Editors (ICMJE), supported by the World Association of Medical Editors, started demanding as a requisite for publication that all clinical trials be registered at the database ClinicalTrials.gov. In 2006, the World Health Organization (WHO) created the International Clinical Trial Registry Platform (ICTRP), which gathers several registry centers from all over the world, and required that all researchers and pharmaceutical industries register clinical trials. Such obligatory registration has progressed and will extend to all scientific journals indexed in all worldwide databases. Registration of clinical trials means another step of clinical research towards transparency, ethics and impartiality, resulting in real evidence to the forthcoming changes in clinical practice as well as in the health situation.

A new number field construction of the lattice E8

Known number theoretical constructions of the lattice E8 use the cyclotomic fields Q(ζ15), Q(ζ20), and Q(ζ24). In this work, an infinite family of Abelian number fields yielding rotated versions of the lattice E 8 is exhibited. © 2012 The Managing Editors.

A gramaticalização de então no português paulista: um estudo pancrônico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Mapeamento das revistas científicas de medicina disponíveis no Portal de Periódicos da Capes que publicam revisões sistemáticas

Pós-graduação em Bases Gerais da Cirurgia - FMB

Intelectualidade e imprensa negra paulista: os casos do Getulino e Progresso (1923-1931)

Pós-graduação em História - FCLAS

Periódicos científicos eletrônicos: apresentação de modelo para análise de estrutura

Pós-graduação em Ciência da Informação - FFC

As crônicas portuguesas de D. João da Câmara na Gazeta de Notícias (1901-1905)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Dedilhado pianístico e suas relações com princípios técnicos e musicais

Pós-graduação em Música - IA

Adaptation to climate change in megacities of Latin America: Regional Learning Network of the research project ClimateAdaptationSantiago (CAS)

The main objective of this publication is to document the current state of urban climate change adaptation practice in Latin America. It is a summary of the three workshops of the Regional Learning Network that was set up under the ClimateAdaptationSantiago project (CAS), encompassing six large Latin American cities (Bogotá, Buenos Aires, Lima, Mexico City, São Paulo and Santiago). It aims to synthesize information on the manifestations and impacts of climate change in those Latin American cities that participated in the network, and above all, governance in the form of concrete actions. The publication is based on information obtained from the participants in the three workshops, but also includes additional scientific input and reflections by the editors. All of this information makes a major contribution to highlighting the different paths these six cities are pursuing in response to climate change. To that end, the publication discusses the various courses of action on climate change adaptation, with the aim of learning from these cases and highlighting practical examples.

As cartas de Chico Xavier: uma análise semiótica

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

A abdicação de D. Pedro I: espaço público da política e opinião pública no final do Primeiro Reinado

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Raduan Nassar e a lavoura dos dizeres: entre Provérbios e Cantares

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

As apropriações e representações de Édouard Claparède no Brasil (1928-1973)

Pós-graduação em Educação - FFC