Switching control of sympathetic activity from forebrain to hindbrain in chronic dehydration

We investigated the mechanisms responsible for increased blood pressure and sympathetic nerve activity (SNA) caused by 2-3 days dehydration (DH) both in vivo and in situ preparations. In euhydrated (EH) rats, systemic application of the AT(1) receptor antagonist Losartan and subsequent pre-collicular transection (to remove the hypothalamus) significantly reduced thoracic (t) SNA. In contrast, in DH rats, Losartan, followed by pre-collicular and pontine transections, failed to reduce tSNA, whereas transection at the medulla-spinal cord junction massively reduced tSNA. In DH but not EH rats, selective inhibition of the commissural nucleus tractus solitarii (cNTS) significantly reduced tSNA. Comparable data were obtained in both in situ and in vivo (anaesthetized/conscious) rats and suggest that following chronic dehydration, the control of tSNA transfers from supra-brainstem structures (e. g. hypothalamus) to the medulla oblongata, particularly the cNTS. As microarray analysis revealed up-regulation of AP1 transcription factor JunD in the dehydrated cNTS, we tested the hypothesis that AP1 transcription factor activity is responsible for dehydration-induced functional plasticity. When AP1 activity was blocked in the cNTS using a viral vector expressing a dominant negative FosB, cNTS inactivation was ineffective. However, tSNA was decreased after pre-collicular transection, a response similar to that seen in EHrats. Thus, the dehydration-induced switch in control of tSNA from hypothalamus to cNTS seems to be mediated via activation of AP1 transcription factors in the cNTS. If AP1 activity is blocked in the cNTS during dehydration, sympathetic activity control reverts back to forebrain regions. This unique reciprocating neural structure-switching plasticity between brain centres emphasizes the multiple mechanisms available for the adaptive response to dehydration.

Consciousness minus retrospective mental time travel

In this paper we apply the concept of mental time travel to introduce the basic features of full-blown conscious experiences (encapsulation in mental models and recollection). We discuss the perspective that Lamme`s `Level 3` experiences can be considered as part of the scope of phenomenological consciousness, in relation to which we emphasize the necessity to consider the different degrees of consciousness and how a particular situation compares to the conscious experiences present in resting states of wakefulness.

Dynamic Changes in the Mental Rotation Network Revealed by Pattern Recognition Analysis of fMRI Data

We investigated the temporal dynamics and changes in connectivity in the mental rotation network through the application of spatio-temporal support vector machines (SVMs). The spatio-temporal SVM [Mourao-Miranda, J., Friston, K. J., et al. (2007). Dynamic discrimination analysis: A spatial-temporal SVM. Neuroimage, 36, 88-99] is a pattern recognition approach that is suitable for investigating dynamic changes in the brain network during a complex mental task. It does not require a model describing each component of the task and the precise shape of the BOLD impulse response. By defining a time window including a cognitive event, one can use spatio-temporal fMRI observations from two cognitive states to train the SVM. During the training, the SVM finds the discriminating pattern between the two states and produces a discriminating weight vector encompassing both voxels and time (i.e., spatio-temporal maps). We showed that by applying spatio-temporal SVM to an event-related mental rotation experiment, it is possible to discriminate between different degrees of angular disparity (0 degrees vs. 20 degrees, 0 degrees vs. 60 degrees, and 0 degrees vs. 100 degrees), and the discrimination accuracy is correlated with the difference in angular disparity between the conditions. For the comparison with highest accuracy (08 vs. 1008), we evaluated how the most discriminating areas (visual regions, parietal regions, supplementary, and premotor areas) change their behavior over time. The frontal premotor regions became highly discriminating earlier than the superior parietal cortex. There seems to be a parcellation of the parietal regions with an earlier discrimination of the inferior parietal lobe in the mental rotation in relation to the superior parietal. The SVM also identified a network of regions that had a decrease in BOLD responses during the 100 degrees condition in relation to the 0 degrees condition (posterior cingulate, frontal, and superior temporal gyrus). This network was also highly discriminating between the two conditions. In addition, we investigated changes in functional connectivity between the most discriminating areas identified by the spatio-temporal SVM. We observed an increase in functional connectivity between almost all areas activated during the 100 degrees condition (bilateral inferior and superior parietal lobe, bilateral premotor area, and SMA) but not between the areas that showed a decrease in BOLD response during the 100 degrees condition.

Managing ServerHotel

This graduate study was assigned by Unisys Oy Ab. The purpose of this study was to find tools to monitor and manage servers and objects in a hosting environment and to remotely connect to the managed objects. Better solutions for promised services were also researched. Unisys provides a ServerHotel service to other businesses which do not have time or resources to manage their own network, servers or applications. Contracts are based on a Service Level Agreement where service level is agreed upon according to the customer's needs. These needs have created a demand for management tools. Unisys wanted to find the most appropriate tools for its hosting environment to fulfill the agreed service level with reasonable costs. The theory consists of literary research focusing on general agreements used in the Finnish IT business, different types of monitoring and management tools and the common protocols used inthem. The theory focuses mainly on the central elements of the above mentioned topics and on their positive and negative features. The second part of the study focuses on general hosting agreements and what management tools Unisys has selected for hosting and why. It also gives a more detailed account of the hosting environment and its features in more detail. Because of the results of the study Unisys decided to use Servers Alive to monitor network and MS applications’ services. Cacti was chosen to monitor disk spaces, which gives us an idea of future disk growth. For remote connections the Microsoft’s Remote Desktop tool was the mostappropriate when the connection was tunneled through Secure Shell (SSH). Finding proper tools for the intended purposes with cost-conscious financial resources proved challenging. This study showed that if required, it is possible to build a professional hosting environment.

Färgperception och grafisk profilering av Hedemora Assistansservie

An inquiring study of literature has been conducted, about the human colour perception (theimpression of colours). The colour has been examined, both as conscious and subconscious signal,and reasons for it’s influence have been exammed.The practical parts of the degree project have been carried out in active collaboration with thecustomer, The Association Hedemora Assistansservice (HASS), which offers handicapped persons astimulating spare time by personal assistance. A graphical profile-programme and an informationfolderhave been produced, easy received by both handicapped (with defective vision) and normallysighted persons. The graphical profile-programme was made in collaboration with the customer.Concerning the information-folder HASS took the main responsibility for the choice of photographswhile layout, text writing, colour-reproduction, original-production and connecting printing workswere made independently. The customer has shown engagement and interest and had a lot of opinionsabout the degree project, of which have been paid attention.

Sustainability & Consumer behavior towards Sustainability in Norway and Sweden

AimSustainability has become an important factor to consider while buying goods and services. People are being more conscious toward environmental impacts of products and services. This attitude has motivated many businesses to develop their production in contact with sustainability. The aim of this paper is to investigate different consumer behaviors toward sustainability in general and in relation to vehicles in Norway and Sweden.ApproachThe project has been embarked by dividing it into two tasks.1. Analyzing past, present and future development, growth and importance of sustainability concept. Describe the role of Government authorities in Norway and Sweden to promote sustainable consumption.2. Investigating important factors of consumer behaviors which influence their buying decision toward sustainable products in general and in relation to sustainable vehicles. Highlight the role of vehicle manufacturing companies to promote sustainable consumption.MethodA research has been conducted in order to explore consumer behavior toward sustainability in Norway and Sweden. Research is based on Document study and primary research which include questionnaire survey with consumers and interviews with vehicle dealers. In addition an expert inquiry is conducted to light up consumer intensions in Norway and Sweden toward sustainability.ResultsThe result of investigation has been revealed in shape of analyses and conclusion at the end. A comparison has been made between primary research and secondary research and findings are overlapping. Sustainable vehicles are being more popular among consumers in Norway and Sweden. Consumption trends are changing over time and environmental friendly attitudes are more developing among Swedish consumers as compared to Norwegian.

La carne recordada : un análisis de la atemporalidad mítica y la subversión religiosa en Pedro Páramo

The aim of the present study is to analyze the representation of the mythic timelessness and the religious subversion in the novel Pedro Páramo (1953) by the Mexican writer Juan Rulfo. The novel is analyzed from a narratological perspective based on the concept of focalization proposed by the French theoretician Gérard Genette. According to Genette it is possible to identify different levels of focalization depending on the position of the narrative voices.The key question in this investigation is if any salvation is possible in the universe of Pedro Páramo and how the mythic timelessness and the religious subversion are represented in the textual intentionality through the narrative voices. The main conclusion is that there is no possible salvation in the fictional universe of Pedro Páramo. The collective sin is so vast that the intermediation between God and the inhabitants of Comala does not work anymore. Thus, the only possible ”salvation” consists in the separation of the soul from the body the people of Comala experience after death. In Pedro Páramo the dead body is liberated from remorses, but - contrary to the Catholic concepts - becomes a conscious materia sentenced to remember eternally.Keywords: Juan Rulfo, Pedro Páramo, narratological analysis, Gérard Genette, textual intentionality, focalization, mythic timelessness, religious subversion, narrative voices.

Värdefull litteratur : Fyra gymnasielärare om samhällsuppdragets etik i förhållande till litteraturen i klassrummet

The ethical aspects of the Swedish Curriculum for the non-compulsory school system, Lpf94, will form the basis of the research in this essay. The ethical aspects constitute fundamental values and goals as well as common tasks that must be carried out by every teacher. Since the school debate focuses a lot on this perspective, which is often mentioned together with the words problematic and contradictory, it will consequently also be the focus of this essay. Here these features are treated in relation to literature in all its forms used by teachers in class, which also represents a part of the school debate. Together ethics and literature form a perspective that lacks research. The goal is to investigate the ethical awareness of teachers in relation to the literature, and find out which ethical decisions are made by teachers and in what ways the ethical aspects of the curriculum is fulfilled. A qualitative method has been used in order to gain results: four upper secondary school teachers/senior high school teachers have been interviewed. The results are presented in interview transcripts which have been analyzed and interpreted in the light of recent studies and research and pedagogical-didactical literature. Accordingly I have been able to draw the conclusions that the ethical features in teaching is not explicit and that there seldom seems to be any conscious ethical reflections in relation to the literature. The ethical aspects are rather invisible and unconscious. However, it is clear that the interviews raise the awareness of the ethical perspective and thus emphasize the growing and developing function of the dialogue. Finally the results have been interpreted from the point of view of the ethical tasks of the teacher in order to make the ethics visible.I detta examensarbete ligger fokus på de etiska aspekterna av samhällsuppdraget i förhållande till den litteratur som lärare använder sig av i klassrumsundervisningen. Eftersom en stor del av skoldebatten handlar om samhällsuppdraget och dess värdegrund utgör också detta perspektiv utgångspunkten för denna undersökning. Målet är att undersöka vilka etiska avvägningar lärare gör i valet av litteratur och på vilket sätt samhällsuppdragets etik blir synlig i lärares arbete. Därmed framkommer också till viss del i vilken omfattning värdegrundsarbetet sker. Genom en kvalitativ undersökningsmetod i form av samtal har fyra gymnasielärare intervjuats. Erhållna resultat har presenterats i form av intervjutranskript som analyserats och tolkats med hjälp av aktuell forskning och pedagogisk-didaktisk litteratur. De slutsatser som kan dras utifrån resultaten är att etiken i lärarnas arbete inte är explicit och att det oftast inte finns en medveten etisk reflektion utifrån litteraturen. Etiken är snarare osynlig och tämligen omedveten. Dock medvetandegörs den under samtalen vilket framhåller dialogens betydelse för utveckling. Vidare framkommer att etiken aldrig är ett mål i sig, utan fungerar mer som medel för att nå andra mål i klassrummet. Slutligen, för att synliggöra etiken, har resultaten tolkats utifrån de etiska krav i samhällsuppdraget som ställs på lärare.

Decisions with Impact on Energy Reduction Opportunities : Swedish manufacturers and buyers of new single-family houses

This article discusses some of the complexities of human decision-making. It aims, in particular, at relating the nature of decision-making to the illusory dichotomies of change and stability, individual actions and cultural sharing. Serving as an illustration to the discussion of the article is ongoing fieldwork in contexts of buying, selling and constructing pre-fabricated detached houses in the central Sweden, and the very specific question of how decisions to install one kind of heating-system rather than another come about. A common reductionism is to narrow down the understanding of decisions about heating systems and energy consumption to conscious choices made by individual householders. I have asked myself whether, on the contrary, anyone actually makes such decisions at all. Perhaps some of these decisions are merely outcomes of interaction between different individuals with their respective responsibilities and focuses of interest.

Bini Customary law of inheritence : a shift in Igiogbe as a case study

Igiogbe cultural heritage has existed since the founding of Bini kingdom without any controversy; however since the Supreme Court decision in Idehen v Idehen the issue of Igiogbe has assumed new dimensions. Igiogbe - the house in which a Benin man lived and died devolves on his first son absolutely; but since the beginning of 20th century litigation as to the real meaning of Igiogbe and who is entitled to inheritance thereof began to increase. Controversies and increase in litigation over Igiogbe has occasioned a shift in the practice, the Bini’s are not conscious of some of these changes, most of them (Bini’s) still claim Igiogbe practices is rigidly adhered to. This study on Igiogbe inheritance in Bini kingdom is therefore carried out with a view to bringing out the changes in Igiogbe cultural practice using legal and anthropological tools to examine the changes. While laying the foundation for the discussion on the main research object the researcher examined the origin and status of customary law in Nigeria. There after I examined Igiogbe inheritance in Bini kingdom. Igiogbe and the issue of first son were critically analyzed with the aid of the research questions bringing out the changes in Igiogbe concept from traditional practice to modern practice. Study shows Igiogbe practice is still relevant in modern Bini kingdom, however, the shift and changes in practice of this cultural milieu has lead me to ask some fundamental questions which I intend to answer in the broader research work in future.

Internet- den nya barnmorskan? : En enkätstudie om hur gravida kvinnor söker information om graviditet och förlossning via Internet

Bakgrund: Internet används globalt inom många områden och aktuell forskning visar att gravida kvinnor använder Internet till att söka information om graviditet och förlossning. En graviditet innebär många frågor hos kvinnan och kvinnor söker efter information för att få en trygghet och försäkran om att allt är normalt med deras hälsa och barnet i magen. Syfte: Syftet är att undersöka gravida kvinnors informationssökning via Internet avseende graviditet och förlossning. Metod: Beskrivande tvärsnittstudie. Datainsamling skedde via en enkätundersökning och data analyserades med deskriptiv och jämförande ansats. Resultat: Nästan alla kvinnor i undersökningen använde Internet för att söka information om graviditet och förlossning. Kvinnorna söker information om barnets utveckling, kost/näring och graviditetslängd i hög utsträckning. Högutbildade kvinnor har andra kriterier för trovärdighet på hemsidor än kvinnor med lägre utbildning. Slutsats: Barnmorskor bör vara medvetna om gravida kvinnors användning av Internet samt själva skapa sig en uppfattning om informationen som de gravida kvinnorna läser på Internet. Vår studie visar att barnmorskors rekommendation av hemsidor på Internet har stor betydelse för gravida kvinnor.  

Vindkraft i Dalarna : Från acceptans och lokalisering till planering och eftertanke

This thesis examines prerequisites for wind power diffusion in a county in Sweden that quite recently was concidered to be of interest for electricty production from renewable energy sources. Three different municipalities: Falun, Mora and Orsa in the county of Dalarna are highlighted.  Their view on permitting processes of wind power installations are investigated. Other actors, such as exploiters and local citizens are also being analysed. This study shows that the local acceptance was very high when the first wind power parks were built, much thanks to local politicians and local citizens. For the politicians the wind power symbolised a key to a better green society, for the local citizens the wind power meant some economical advantages. The first wind power parks were localised to areas because of good wind conditions and social factors, especially from local communities. However, results from this study shows that the acceptance for wind power the last few years, in generel, has decreased.  The local authorities have also been conscious of some negative consequenses from already built wind power parks.  As a response they started to add planning tools to the permitting process.

Essentialism i religionsundervisningen : Ett religionsdidaktiskt problem

Essentialist concepts of religion are common in the teaching of religion in schools and to a certain extent also in the academic discipline of religious studies. In this article, a number of problems with essentialist perceptions of religion are discussed. In the first part of the article a thesis is maintained, according to which essentialist conceptions of religion or specific religions are too limited to be of value in the teaching of religion. This is done through examples of essentialist expressions about religion. The examples are grouped according to a typology of different kinds of essentialism. Two main categories, each with two sub-categories are identified. Thus, the category of essentialism regarding the substance of religion is divided into transcendental or theological essentialism (which presupposes the existence of a sacred power of some kind, the experience of which is the basis for religion), and core essentialism (where it is presupposed that certain ideas or concepts constitute religion as a general category or specific religions). Likewise, the category of essentialism regarding the function of religion has two sub-categories: positive and negative essentialism. These kinds of essentialism presuppose that religion or specific religions are inherently good or harmful respectively to human beings. Examples from each of these categories are given and discussed. In the second part of the article, Benson Saler’s open concept of religion is presented as an alternative to essentialist or bounded perceptions. It is based on Ludwig Wittgenstein’s idea of family resemblances and on prototype theory. In connection with this, it is argued that a certain kind of conscious ethnocentrism is needed as a point of departure in the study and teaching of religion. The metaphor of education as a journey from the familiar out into the unfamiliar and back again is suggested as a possible pattern for such teaching. Finally,some examples of non-essentialist ways to introduce religions are offered.

Film som kommunikation : En studie av gymnasieungdomars filmarbete

The starting point for this work was a discussion between my supervisor and myself during my teaching training. The discussion concerned the appropriateness of allowing students make films with sexual content. Film gives young people the opportunity to express their feelings and broaden their views. If the film then disseminates to unknown people via in-ternet, which it most likely will do, maybe it is no longer so positive. The aim of this study is to shed light on various aspects of identity and ethics that are important to keep in mind when young people in school make films. These aspects are to avoid making young people vulnerable to abuse and improper influence. One aim is also to highlight the advantages of making films in school. The study is inspired by hermeneutic interpretive and based on qualitative interviews. The informants are four students at the age of 18-19 at two different schools in one municipality in Sweden.The results of the study show that it is important for the informants that the films are pro-duced in an aesthetically good way so that it appeals to the audience. Two of the infor-mants have a specific audience and make more conscious choices, so that the audience will understand what is said. The study shows that the more a filmmaker considers the audi-ence, the more consciously he or she uses film as communication. To get positive feedback is important, but it is mostly friends of the filmmakers that actually comment. To get nega-tive comments is regarded as a disadvantage when placing material on the internet. Howev-er, none of the informants in the study have received negative comments on what has been posted. The opinions about what the informants believe is inappropriate to post on inter-net or to make films about regards sexuality and violations. Earlier studies show that mate-rial can, because it is interesting to other people, become widespread. For this reason it is important for teachers to have conversations with students about their preferences and opinions on various issues. Adults need to interfere in the young people's world, while be-ing open to their opinions. Then the young people's value system will be built up and give them a safe tool that helps them to avoid improper influence.

Fyrtiotalisterna och äldreomsorgen : massmediala konstruktioner av en ny sorts omsorgstagare

Baby boomers and elderly care: expectations in print media about a new kind of care users The Swedish baby boomer generation – known as the forties generation – has been characterized as youthful and powerful. At present, members of this generation are entering the category of old age and in about ten years they will start reaching ages where the likelihood of encountering elderly care increases significantly. The present study reports on how this expected meeting has been discussed in Swedish newspapers. Data consisted of 481 articles during the period 1995–2012 and was analyzed through qualitative content analysis. Results show that the generation was predicted to become a new type of demanding and self-conscious care users. Claims were backed by descriptions of formative events and typical characteristics that were projected onto a future as care user. Such projections tended to portray care users of present time as passive and submissive, and partly responsible for problems associated with elderly care