839 resultados para SOLORZANO Y PEREYRA, JUAN DE


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Discurso del Ilmo. y Rvmo. Sr. D. Juan Maura y Gelabert, Obispo de Orihuela en la Sesion de Clausura de la Semana Social de Sevilla (22 de noviembre de 1908)

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Palau, 158.943

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Varias escalas

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Explotación de la mina de galena argentífera "Esperanza"

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Proyecto de dinamo de corriente contínua

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Contiene otro catecismo del autor con paginación propia

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Fecha de 1678 tomada de texto

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A deficiency in essential fatty acid metabolism has been reported in plasma from patients with cystic fibrosis (CF). However, its etiology and role in the expression of disease is unknown. The objective of this study was to determine whether alterations in fatty acid metabolism are specific to CF-regulated organs and whether they play a role in the expression of disease. A membrane lipid imbalance was found in ileum, pancreas, and lung from cftr−/− mice characterized by an increase in phospholipid-bound arachidonic acid and a decrease in phospholipid-bound docosahexaenoic acid (DHA). This lipid imbalance was observed in organs pathologically affected by CF including lung, pancreas, and ileum and was not secondary to impaired intestinal absorption or hepatic biosynthesis of DHA. As proof of concept, oral administration of DHA to cftr−/− mice corrected this lipid imbalance and reversed the observed pathological manifestations. These results strongly suggest that certain phenotypic manifestations of CF may result from remediable alterations in phospholipid-bound arachidonic acid and DHA levels.

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Silverio Lanza.-Azoría-Pío Baroja.-Eduardo Marquinn.-Alberto Insúa.-Emilio Guanyabéns.-Miguel de Unamuno.-Vincente Medina.-Pedro Corominas.-Miguel Ciges Aparicio.-Pedro de Répide.-Los nuevos románticos (Villaespesa, Jiménez, Díez-Canedo)

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Mode of access: Internet.

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Mode of access: Internet.

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"Obras del autor": 1st leaf at end of book.