933 resultados para Oliver, David


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To understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a core set of 14,345 orthologs shared among seven mammalian species of which 1217 are absent or undetected in noneutherian (marsupial or monotreme) genomes. Cattle-specific evolutionary breakpoint regions in chromosomes have a higher density of segmental duplications, enrichment of repetitive elements, and species-specific variations in genes associated with lactation and immune responsiveness. Genes involved in metabolism are generally highly conserved, although five metabolic genes are deleted or extensively diverged from their human orthologs. The cattle genome sequence thus provides a resource for understanding mammalian evolution and accelerating livestock genetic improvement for milk and meat production.

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The imprints of domestication and breed development on the genomes of livestock likely differ from those of companion animals. A deep draft sequence assembly of shotgun reads from a single Hereford female and comparative sequences sampled from six additional breeds were used to develop probes to interrogate 37,470 single-nucleotide polymorphisms (SNPs) in 497 cattle from 19 geographically and biologically diverse breeds. These data show that cattle have undergone a rapid recent decrease in effective population size from a very large ancestral population, possibly due to bottlenecks associated with domestication, selection, and breed formation. Domestication and artificial selection appear to have left detectable signatures of selection within the cattle genome, yet the current levels of diversity within breeds are at least as great as exists within humans.

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Includes bibliography

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Pós-graduação em Agronomia (Entomologia Agrícola) - FCAV

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Inversión extranjera directa y desarrollo: la experiencia del Mercosur / Daniel Chudnovsky y Andrés López. -- Desarrollo de ventajas competitivas: pymes exportadoras exitosas en Argentina, Chile y Colombia / Dario Milesi, Virginia Moori, Verónica Robert y Gabriel Yoguel. -- Efectos de la capacitación en la competitividad de la industria manufacturer / Ramón Padilla y Miriam Juárez. -- La inserción laboral de los jóvenes: características, tensiones y desafíos / Jürgen Weller. -- La globalización de la atención de la salud: oportunidades para el Caribe / Richard L. Bernal. -- La protección social en el Caribe de habla inglesa / Oliver Paddison. -- Reforzando un pilar fiscal: el impuesto a la renta dual a la uruguaya / Alberto Barreix y Jerónimo Roca. -- Migraciones internacionales y desarrollo: el impacto socioeconómico de las remesas en Colombia / David Khoudour-Castéras. -- Agentes extrasectoriales y transformaciones recientes en el agro argentine / Clara Craviotti. -- Jueces de la Revista de la CEPAL 2005-2006. -- Orientaciones para los colaboradores de la Revista de la CEPAL. -- La Revista de la CEPAL en Internet . -- Publicaciones recientes de la CEPAL.