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Copy of correspondence responding to a November 16, 1652, letter from Odell regarding his daughter's illness, which Winthrop speculates is hemiplegia. According to Winthrop, "The cure depends upon the knowledge of the right cause, and not only that but the constand and due aplication of such things as may conduce them thereto, which is difficult to doe at a distance." Winthrop further writes that he did not at present have medicine to send for her condition, but recommends "some general things that might be helpfull." These included keeping the child warm with fox or rabbit furs, an ointment consisting of herbs, wax, castor oil, worm grease, fox grease, or an ointment of balsam. Winthrop writes he has sent an ointment, but does not specify its ingredients. His other suggestions for treatment include cupping without scarification, and an decoction containing sarsaparilla, guaiacum, and spirit of rosemary.

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Correspondence seeking Winthrop's advice regarding treatment of his daughter, who had been vomiting and suffering insomnia and dry mouth for several days

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Correspondence requesting Winthrop's advice for treating a condition Rood describes as a "falling out of [the] wome" (prolapsed uterus) that occurred after her first childbirth and has worsened with the birth of her second child.

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Correspondence soliciting Winthrop's advice for treating an illness in Samford's wife, whose symptoms included pain and weakness in her back and legs.

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Correspondence describing a hernia Sherman was suffering, and asking for Winthrop's advice and a "little of [your] red powder."

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Correspondence requesting advice on treatment and medicine for his daughter-in-law, who was ill with pain, vomiting, and a cough.

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Correspondence seeking advice from Winthrop about his 23-week-old son, who was suffering from jaundice and a cough. Stone writes the course of treatment for the infant, on the advice of a Mrs. Hooker, had included barbaric bark boiled in beer with saffron twice daily, as well as turmeric. He also administered Winthrop's purging powder, and Stone asks if he should continue giving the powder and at what dose, and if there is any other medicines Winthrop would prescribe.

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Correspondence requesting directions for administering medicine Winthrop had sent for Towslande's wife.

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Correspondence seeking advice on treatment of a urinary condition.

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Correspondence requesting advice for treating occasional fits of pain and cold Ward was suffering.

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Correspondence requesting advice and medicine for his wife, who was suffering from symptoms that included a "swiming" feeling in her head, melancholy, and hot flashes.

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Commission of Noah Cooke, Jr., as chaplain in the Continental Army, signed by John Hancock, 1 January 1776.

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Correspondence regarding the donation of several collections to the Boston Medical Library, including the John Winthrop papers