Lottery Action, Vol. 16, No. 18

Iowa Lottery newsletter for lottery retailers.

Special investigation of the City of Truro for the period January 1, 2003 through February 18, 2009

Special investigation of the City of Truro for the period January 1, 2003 through February 18, 2009

Inflammatory caspases in innate immunity and inflammation.

Caspases are best known for their role in apoptosis. More recently, they have gained prominence as critical mediators of innate immune responses. The so-called 'inflammatory caspases' include human caspase-1, -4, -5 and -12 and murine caspase-1, -11 and -12. Of these, caspase-1 is best characterized and serves as the prototype for our understanding of the processing, activation and function of inflammatory caspases. Like their apoptotic counterparts, inflammatory caspases are produced as inactive zymogens and require activation to become proteolytically active. Caspase-1 is activated within the inflammasome, a large cytosolic protein complex that is induced by a growing number of endogenous, microbial, chemical or environmental stimuli. The importance of caspase-1 in initiating innate immune responses is demonstrated by its role in cleaving pro-IL-1 beta and pro-IL-18 to their biologically active forms. New functions have also been implicated, as these proteases and the mechanisms underlying their activation and regulation emerge as important mediators of human health and disease.

Business Sphere, Vol. 18, no.2

The biosciences industry significantly impacts Iowa’s economy. Kemin, Integrated DNA Technologies, Archer Daniels Midland Co., Roquette America, Cargill, Monsanto and DuPont’s Pioneer Hi-Bred International are only a few of Iowa’s 1,800 bioscience companies employing more than 83,000 people. Everyday, Kemin and other Iowa life sciences companies seek to commercialize new bioscience innovations. Together with Iowa’s outstanding business climate, a skilled, well educated and adaptable workforce, and an enviable quality of life, Iowa is providing bioscience companies with an exciting new resource to assist us in our endeavors: The Biosciences Alliance of Iowa.

Business Sphere, Vol. 18, no.4

As the nation’s leading producer of ethanol and biodiesel, Iowa is building upon its national reputation as an innovative renewable fuel and energy leader by aggressively pursuing more wind energy production. We invite you to take a closer look at Iowa as we harness the winds of renewable energy

Business Sphere, Vol. 18, no.3

Iowa may be known for some of the world’s most fertile cropland, but in recent years, we’ve become fertile ground for rapid growth in information technology as well. From the recent “plug-in” of Google’s $600-million Council Bluffs data center to Microsoft’s planned half-billion-dollar West Des Moines expansion to IBM’s 1,300-job-creating expansion in Dubuque, technology leaders are finding Iowa a place to grow. And why not? Iowa has a supportive business climate and its infrastructure — physical and human — give our technology companies the competitive advantages that allow them to grow and prosper.

Business Sphere, Vol. 18, no.1

Information technology is a strong and important sector of the Iowa economy employing 30,000 Iowans at more than 2,000 companies, according to a new analysis from Battelle Institute consultants. The strength of Iowa’s IT industry is based in the service-segment. Internet and data services, communications network services, and software and computer services constitute 81 percent of all IT employment. Slightly ahead of U.S. trends, these service sectors compose the backbone of Iowa’s IT industry,

[Lettre autographe signée de Giuseppe Verdi adressée à Escudier, Gênes, 18 juillet 1866]

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[Lettre autographe signée de Giuseppe Verdi à Escudier, Busseto, Sant'Agata, 18 avril 1867]

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[Lettre autographe signée de Giuseppe Verdi à Escudier, Sant'Agata, 18 avril 1869]

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[Lettre autographe signée de Giuseppe Verdi adressée à Escudier, Naples, 18 janvier 1873]

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