Validação de métodos nociceptivos elétrico, mecânico e térmico para avaliação de dor de equinos tratados com metadona associada à detomidinaou acepromazina

Pós-graduação em Anestesiologia - FMB

Seqüelas em dentes permanentes após trauma nos predecessores decíduos e sua implicação clínica

In regarding to the high prevalence of traumatic dental injuries in primary teeth and the possible disturbances on developing permanent successor germs, an early diagnosis and an adequate establishment of treatment planning are very important to minimize the damage caused by the trauma. Sequelaes can affect the coronal portion (white or yellow-brown discoloration associated or not with enamel hipoplasia, dilacerations of the crown), the root portion (dilaceration, duplication or cessation of root formation) or the whole successor permanent tooth (odontoma sequestration or disturbances of permanent successor eruption). The aim of this study is to make a literature review of the developmental disturbances of permanent teeth followed by traumatic injuries to theirs primary predecessors and to present cases reports to advise the dentists, their patients and parents about the damage that developing permanents teeth can undergo.

Quantificação de endotoxinas e sua relação com sinais / sintomas e volumetria da lesão periapical e do canal radicular em dentes com infecção endodôntica primária

Pós-graduação em Odontologia Restauradora - ICT

Avaliação da espessura do osso parietal como região doadora de enxertos ósseos.

Introduction: The study of graft donor sites, whether from the anatomical, physiological or morphological point of view, has become a topic of current interest, due to the increasing number of patients needing facial bone reconstruction for various reasons. Purpose: In view of the need to constantly improve surgical techniques for autogenous bone graft harvesting, still considered the best choice for facial bone reconstruction, this paper describes an anatomical study on dry skulls in order to evaluate the average thickness of the parietal bone. Material and Methods: Measurements of this bone were taken with a goniometer, at four previously defined points, in the region that is often used as a donor site, in 49 dry skulls (98 parietal bones). The results were evaluated using the T test. Results: Thickness was measured at four predetermined points. The mean values (Point A = 4898mm, B = 4517mm, C = 6185mm, D = 4280mm) show that the bone can be even thinner than previously reported in the literature in other studies of the same nature. The largest bone thickness is in the medial and posterior region. Conclusion: A knowledge of these anatomical characteristics is helpful in preventing possible surgical complications, as well as making it safer for the surgeon to remove this graft and providing more information on whether or not to indicate this region as a bone graft donor site.

Dimensões das furcas de primeiros pré-molares superiores e sua relação com curetas periodontais

The aim of this in vitro study was to comparatively evaluate the mesio and distal furcation entrance measurements of first maxillary premolar. The measurements were compared with different curette blades. A caliper was used by an examinator to acquire the measurements of root trunk (TR); 1 mm (D1) and 2 mm (D2) both below the furcation entrance. For this study Gracey, Mini Gracey, Padua Lima (PL) and Goldman Fox 4 curettes (Millenium) were selected. Measurements of DT - total distance of the active blade length, DI - width of the active blade, DM - width of the medium part of the active blade were obtained for the curettes. The measurements were obtained in both the coronary face and in the lateral face. The data TR, D1 and D2 presented normal distribution and were statistically analyzed by paired t-test. Statistically significant differences were found in the mesial root trunk region (TR) of both premolars. The mean of the measurements was greater than the distal. Mean and standard deviation were obtained, and both Gracey and Mini Gracey showed mean measurements compatible with the closer furcation entrance (D1 - 1 mm). Goldman Fox 4 showed adaptation only in the mesial face, and Padua Lima showed no access to any of the faces. Thereby it is concluded that the access of the furcation is narrow (D1). The mesial face of the root trunk (TR) showed mean measurement greater than distal face. Gracey and Mini Gracey curettes demonstrated to be compatible for both faces, mesial and distal of the first maxillary premolars studied.

Fracture resistance of endodontically-treated teeth submitted to bleaching treatment with hydrogen peroxide and titanium dioxide nanoparticles photoactivated by LED-laser

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Response of human pulps to different in-office bleaching techniques: preliminary findings

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Interação entre as vias de sinalização de receptores serotoninérgicos e Β-adrenérgicos em artéria femoral de ratos

Fundamento: A doença coronária tem sido amplamente estudada em pesquisas cardiovasculares. No entanto, pacientes com doença arterial periférica (DAP) têm piores resultados em comparação àqueles com doença arterial coronariana. Portanto, os estudos farmacológicos com artéria femoral são altamente relevantes para a melhor compreensão das respostas clínicas e fisiopatológicas da DAP. Objetivo: Avaliar as propriedades farmacológicas dos agentes contráteis e relaxantes na artéria femoral de ratos. Métodos: As curvas de resposta de concentração à fenilefrina contrátil (FC) e à serotonina (5-HT) e os agentes relaxantes isoproterenol (ISO) e forskolina foram obtidos na artéria femoral de ratos isolada. Para as respostas ao relaxamento, os tecidos foram contraídos com FC ou 5-HT. Resultados: A potência de classificação na artéria femoral foi de 5-HT > FC para as respostas contráteis. Em tecidos contraídos com 5-HT, as respostas de relaxamento ao isoproterenol foram praticamente abolidas em comparação aos tecidos contraídos com FC. A forskolina, um estimulante da adenilil ciclase, restaurou parcialmente a resposta de relaxamento ao ISO em tecidos contraídos com 5-HT. Conclusão: Ocorre uma interação entre as vias de sinalização dos receptores β-adrenérgicos e serotoninérgicos na artéria femoral. Além disso, esta pesquisa fornece um novo modelo para estudar as vias de sinalização serotoninérgicas em condições normais e patológicas que podem ajudar a compreender os resultados clínicos na DAP.

Perception of the informed consent form by participants in clinical trials

To understand the perception of the participants in controlled clinical trials (CCTs) about the informed consent and describe the meaning of their participation in the research. Qualitative study using the focus group technique. The sample was composed of 19 patients who participated in clinical trials about hypertension and coronary disease in a specialized cardiologic hospital located in the city of Sao Paulo. The methodological framework used was the content analysis. Some of the participants were aware of the real objective of these studies while others had misperceptions. The reading of the informed consent is not always done and, when it is done, the patient does not understand it. The lack of understanding about the term ''placebo'' was mentioned by some participants. The motivation to participate was the personal benefit. This study shows that obtaining the informed consent in CCTs is complex and that there is the need to adapt the structure and application of this document, in order to protect the participants and improve the quality of clinical trials performed in the country.

Avaliação e correlação da presença de endotoxinas e MMP-3, -8 e -9 em canais radiculares com necrose pulpar submetidos ao tratamento endodôntico - estudo in vivo

It is know that endotoxin and various matrix metalloproteinases (MMPs) are involved in the development of periapical lesions. The purpose of this study was to evaluate and correlate the presence of endotoxins and MMP- 3, MMP-8 and MMP-9 in root canals of teeth with necrotic pulp and periapical lesion before, during and after the biomechanical preparation (PBM) using a combination of different irrigations solutions and intracanal dressing. Thirty-three single-root teeth with a diagnosis of pulp necrosis and periapical lesion radiographically visible were selected. Immediately after the coronal opening was collected the first sample from the root canal content. Then, all canals were prepared (cervical and middle thirds) by oscillatory instruments (EndoEze) and irrigated by 2.5% NaOCl. After, a manual preparation was made for the apical third and the teeth were divided into three groups according to the irrigation protocol: G1) 2.5% NaOCl (4 manual files); G2) 2.5% NaOCl (2 manual files) + [Ca (OH)2 0.14%] (2 manual files) and G3) 2.5% NaOCl (2 manual files) + polymyxin B (2 manual files). After the PBM, the second sample was collected; then the third collect was performed after using EDTA final flush. The fourth sample was collected 14 days after placing the dressing [2% chlorhexidine gel + Ca(OH)2]. Quantification of endotoxins was performed by a kinetic chromogenic lysate from amoebocytes of Limulus (LAL) and quantification of MMPs by ELISA assay. The results were analyzed statistically by Kruskal-Wallis and Dunn's test (5%) and ordinal Spearman correlation. Presence of endotoxin was observed in 100% of cases and G3 showed the greatest reduction of endotoxins from the 1st to the 2nd samples (97%), being statistically similar to G2 (84.2%) and different from G1 (49.4%) (p<0.05). The intracanal dressing promoted a significant reduction of endotoxin, no difference among the groups. For...

Interdisciplinaridade do plano de tratamento após reimplante dentário: relato de caso

O tratamento de escolha para a avulsão dentária é o reimplante dentário, no entanto diversos fatores interferem no prognóstico e a reabsorção radicular é a principal seqüela podendo levar a perda dentária. O objetivo do trabalho foi relatar um caso clínico de reimplante dentário com perda dentária por extensa reabsorção radicular e os planos de tratamento instituídos para reposição do dente perdido. Paciente após acidente motociclístico apresentou avulsão dentária e fratura coronária do elemento 21 e subluxação e fratura coronária do 11. Após quatro anos do reimplante o dente foi perdido por reabsorção radicular externa. Um novo plano de tratamento foi instituído e como a paciente apresentava uma maloclusão foi realizado um tratamento ortodôntico e uma cirurgia ortognática seguido da colocação de um implante para reposição do 21. Como não ocorreu a osseointegração do implante após três tentativas foi realizada uma prótese fixa adesiva associada à laminado de porcelana para o restabelecimento da função e a estética. Desta forma a interdisciplinaridade permitiu a elaboração de planos de tratamento, capaz de eliminar os imprevistos e conduzir o caso a um sucesso.

Avaliação dos fatores críticos para a seleção e aplicação clínica dos pinos de fibra: relato de caso cliínico

Teeth that have lost much of their coronal tooth structure need intraradical devices to achieve a desired retention of the restorative material, restoring aesthetics and function to the patient. For this purpose, various types of intracanal posts have been studied, of wich the fiber posts have been highlighted with its increasing use in the dental market. The purpose of this study was to present a clinical case of using fiberglass post. As well as critically analyze the published works and points of controversy described by different authors related to factors such as different protocols cementation, surface treatments pins, fracture toughness and compression, the possibility of microleakage, diameter and length of the pin, and the various materials used in conjunction with the intracanal retainers. Thus, we concluded that fiber posts showed as an excellent alternative for anterior teeth, since have least 2 mm of tooth remaining.

Estética em sistema metal free associado a núcleos metalocerâmicos personalisados

The evolution of ceramic systems currently allows the manufacture of prosthesis similar to the natural teeth, meeting the expectations of patients. However, when using vitreous ceramic the color of substrate is significant for the esthetic result, requiring planning aesthetic cores when involved reconstruction of endodontically treated teeth without coronal structure. Thus, the aim of this study to describe a case report of aesthetic rehabilitation in upper anterior teeths using vitreous ceramic system for the reconstruction of elements: 11, 12, 21 and 22 after endodontically treated. It was emphasized the removal of crowns and manufacture of custom cast post and core with ceramic in coronal portion, prioritizing the aesthetic result. Through the clinical results observed can be seen that the use of custom cast post and core with ceramic in association lithium disilicate glass ceramics provided a satisfactory aesthetic result.

Restauração transcirúrgica como alternativa na resolução das perfurações endodônticas

The endodontic perforations are iatrogenic communications that result in a communication between the endodonto and periodontium. This occurrence represents about 10 % of cas- es of failure in endodontic treatment. The management may vary and is related to the drilling site endodontic. This paper aims to report a case of iatrogenic perforation and one of the possible alternatives for the treatment of endodontic perforations -level cervical tooth. During the opening coronary perforation occurred due to improper slope cervical penetration drill. Considering the drilling site, we opted for sealing com- posite resin after surgical access and absolute isolation. After sealing, the channel was filled with medication and instru- mented based on calcium hydroxide. Later the canal was obturated by lateral condensation technique with Sealapex. The radiographic follow-up showed regression of the lesion and the clinical silence confirmed the success of the treatment.

Emprego de ma teriais rest auradores adesivos direto no ângulo incisal de incisivos centrais fra turados

A case report of a patient who presents as chief complaint presence of stained restorations in the anterior teeth. After analysis and discussion of the clinical therapeutic approaches to be adopted, it was observed the presence of type class IV restorations on teeth 11 and 21, due to an oblique coronal fracture in the past. But the patient was not satisfied with the aesthetic result, then where was planned the realization of the removal of the restorations, for subsequently be used direct restorative materials for the correction of form, function and esthetics. The final result showed that the restorations were able to return the form, function and aesthetic dental, thereby evidencing the proven development of restorative dentistry in the solution of aesthetic problems.