995 resultados para 1593-1652
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This thesis focused on the situation of family members of persons with psychotic illness, particular on their experience of the approach of the healthcare professionals and of their feelings of alienation regarding the professional care of their family member. A further aim was to explore how siblings who have participated in a support group for siblings experienced their situation. A questionnaire was developed that enabled the aims of this thesis to be investigated (I). Seventy family members from various parts of Sweden participated, and data were collected via the questionnaire developed in study I (II-III). Thirteen siblings who previously had participated in a support group participated in follow-up focus groups interviews (IV). The questionnaire developed was shown to be reliable and valid in these studies (I). In many cases, the participants had experienced an approach from professionals that indicated that they did not experience openness, confirmation and cooperation, and that they felt powerless and socially isolated in relation to the care. There was also found to be a certain degree of association between how the participants experienced the approach and whether they felt alienation (II). The majority of the participants considered openness, confirmation, and cooperation to be important aspects of professional’s approach. The result also identified a low level of agreement between the participants’ experience and what they considered to be significant in the professional’s approach (III). The findings revealed the complexity of being a sibling of an individual with psychotic illness. Participating in a support group for siblings can be of importance in gaining knowledge and minimizing feelings of being alone (IV). Although the psychiatric care services in Sweden have been aware of the importance of cooperating with family members, the results indicated that there is a need for further research in this area.
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Entrepreneurs are portrayed as salient drivers of regional development and for a number of years nascent entrepreneurs have been studied in a large number of countries as part of the Global Entrepreneurship Monitor project and the Panel Study of Entrepreneurial Dynamics. Scholars have devoted much effort to investigating factors that determine how individuals engage in entrepreneurial activities, with most of the discussion limited to business start-ups. However, since this type of project does not follow identical nascent entrepreneurs over time, limited knowledge exists about their development and whether they stay in this nascent phase for a long time. In practice, it is common for entrepreneurs to run a business and at the same time work in wage work, so-called combining entrepreneurs. In Sweden, almost half of all business owners combine wage work with a business. However, not all combining entrepreneurs will eventually decide to leave the wage work and invest fully in the business. Consequently, much research has focused on the first step of entering entrepreneurship full time, but less has focused on the second step, the transition from the combining phase to full-time self-employment. The aim of this thesis is therefore to contribute to the theory of entrepreneurship by gaining a deeper understanding of combining entrepreneurs and their motives and intentions. In the context of combining entrepreneurs, the theory of identity, resources and choice overload has been used to examine how entrepreneurs’ age (when starting the business), entrepreneurial tenure (the length of engagement in the side-business), hours spent (weekly involvement in the side-business), involvement in entrepreneurial teams (leading the business with one or more partners) and involvement in networks (business networks) influence their passion for engaging in entrepreneurship while sustaining wage work. Different categories of combining entrepreneurs and their intentions have also been examined. A survey was administered to 1457 entrepreneurs within the creative sector in two counties in Sweden (Gävleborgs County and Jämtlands County). Since there were no separate mailing lists to only combining entrepreneurs, the survey was sent to all entrepreneurs within the chosen industry and counties. The total response rate was 33.5 percent and of them 57.6 percent combined, yielding 262 combining entrepreneurs who answered the questionnaire. The survey was then followed up with eight focus group interviews and two single interviews to validate the answers from the questionnaire. The results indicate three types of combining entrepreneurs: nascent – with the intention to leave the combining phase for a transition into full-time self-employment, lifestyle – with the intention to stay in the combining phase, and occasional – with the intention to leave the combining phase for full-time wage work and close down the business. Transitioning fully to self-employment increases with the individual’s age. Also, a positive interactive effect exists with involvement in entrepreneurial networks. The results also indicate that the ability to work with something one is passionate about is the top motive for combining wage work with a side-business. Passion is also more likely to be the main motive behind the combining form among individuals who are older at business start-up, but passion is less likely to be the main motive behind the combining form among individuals who spend more time on the business. The longer the individual has had the side-business, the less likely passion is the main motive behind the combining form, and passion is less likely to be the main motive among those who are part of an entrepreneurial team.
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A hiperamonemia é um achado comum em crianças com acidemia metilmalônica, um erro inato do metabolismo caracterizado por retardo mental, convulsões e acúmulo tecidual de ácido metilmalônico (MMA). Embora existam evidências de que o MMA induza convulsões por inibição da sucinato desidrogenase (SDH), muito pouco se sabe sobre a contribuição da hiperamonemia para o desenvolvimento das convulsões nestes pacientes. No presente estudo investigou-se os efeitos do acetato de amônio sobre a ação convulsivante do MMA in vivo e do cloreto de amõnio sobre a inibição da SDH estriatal induzida pelo MMA in vitro. Ratos adultos foram injetados com acetato de amônio (1,5 mmol/kg, s.c.) ou acetato de sódio (1,5 mmol/kg, s.c.) e, após 5 minutos, injetados unilateralmente no estriado com MMA (3 µmol/µl) neutralizado para pH 7,4 com NaOH ou NaCl (4,5 µmol/µl). O pré-tratamento com acetato de amônio aumentou o número e durações dos episódios convulsivos induzidos pelo MMA. O cloreto de amônio não teve efeito sobre a atividade da sucinato desidrogenase e não alterou a inibição da SDH induzida pelo MMA in vitro. Estes resultados sugerem que a amônia potencializa os efeitos comportamentais induzidos pelo MMA por mecanismos que não envolvam adicional inibição da SDH. Este estudo provê evidências de que a hiperamonemia pode potencializar os efeitos neurotóxicos do MMA.
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Este trabalho desenvolve-se na área da Lingüística Aplicada ao Ensino do Espanhol como Língua Estrangeira. O propósito é o de examinar as provas de espanhol dos vestibulares de três Instituições de Ensino Superior de Porto Alegre e Grande Porto Alegre, Rio Grande do Sul, Brasil, no período compreendido entre os anos de 1996 a 2000, para depreender delas o tipo de conhecimento lingüístico exigido do candidato. Empregamos como base metodológica a avaliação formativa, com enfoque qualitativo na interpretação das informações e quantitativo na coleta e exposição dos dados, resultando em um quadro descritivo da realidade das provas examinadas. O estudo caracteriza-se como exploratório, sem levantamento de hipóteses. A falta de pesquisas sobre as provas de espanhol nos vestibulares, e de literatura específica sobre o assunto resultou na busca de uma base teórica que desse suporte a uma análise clara e ajustada ao objetivo. Teóricos clássicos como Saussure (1974), Bloom (1983) até autores contemporâneos como Ortega Olivares (1990), Orlandi (1987) e Wiggins e McThige (1998) constituíram o referencial teórico do trabalho. A análise das provas de espanhol foi organizada tendo em vista os conceitos de Orlandi sobre tipos de discurso, o de Wiggins e MacThige sobre os tipos de perguntas de compreensão e de Ortega Olivares sobre o conceito de gramática. Os resultados apontam para a presença dos discursos autoritário, lúdico e polêmico com a predominância desse último. As perguntas de unidade preponderam sobre as do tipo essencial e o conhecimento gramatical, em grande parte, ainda de base estruturalista indicam que uma nova postura deva ser adotada em relação à elaboração das provas de vestibular e à abordagem do conteúdo.
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Ilustração componente do jogo “QuiForca (http://www.loa.sead.ufscar.br/quiforca.html)” desenvolvido pela equipe do Laboratório de Objetos de Aprendizagem da Universidade Federal de São Carlos (LOA/UFSCar).
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Ilustração componente do jogo “Ortotetris (http://www.loa.sead.ufscar.br/ortotetris.html)” desenvolvido pela equipe do Laboratório de Objetos de Aprendizagem da Universidade Federal de São Carlos (LOA/UFSCar).
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Estudaram-se o perfil eletroforético das proteínas liquóricas e a cota de albumina em cães sem e com cinomose na fase neurológica e não-neurológica. A punção da cisterna magna para a obtenção de amostras de liquor realizou-se em 30 cães. Analisaram-se teores de proteínas totais, cota de albumina e fracionamento eletroforético das proteínas liquóricas em gel de agarose. Os resultados foram semelhantes nos cães normais e nos cães com cinomose sem sinais neurológicos e significativamente elevados no grupo de cães com cinomose apresentando sinais neurológicos. O estudo do quadro protéico do líquido cérebroespinhal foi útil e contribuiu significativamente na detecção de lesões ao sistema nervoso central e de danos à barreira hematoencefálica durante a fase neurológica da cinomose.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Pygmalion (1913), by George Bernard Shaw (1856-1950), has many studies in literary criticism. However, this study brings a new interpretation to Shaw s play based on Harold Bloom s theory and methodology, that is, the anxiety of influence and the dialectic of revisionism. Through the analysis of poetic influence and the dialectic of love, we can see that Pygmalion represents an apophrades in relation to William Shakespeare s The Taming of the Shrew (1593) and Ovid s myth of Pygmalion and Galatea in Metamorphosis (c. 14), which creates a family romance between the three stories. Shaw s play surpasses The Taming of the Shrew when it shows the possibility of the relation between this parent poem and Ovid s myth, which it is also its parent poem, and because it represents a strong misreading of Shakespeare s play as well as of Ovid s myth.
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The mechanical properties of metals with bcc structure, such as niobium and its alloys, have changed significantly with the introduction of heavy interstitial elements. These interstitial elements (nitrogen, for example), present in the alloy, occupy octahedral sites and constitute an elastic dipole of tetragonal symmetry and might produce anelastic relaxation. This article presents the effect of nitrogen on the anelastic properties of Nb-1.0 wt% Zr alloys, measured by means of mechanical spectroscopy using a torsion pendulum. The results showed complex anelastic relaxation structures, which were resolved into their constituent peaks, representing each relaxation process. These processes are due to stress-induced ordering of the interstitial elements around the niobium and zirconium of the alloy.
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Non-audio signals have been recorded in the flash ROM memory of a portable MP3 player, in WAV format file, to examine the possibility of using these cheap and small instruments as general-purpose portable data loggers. A 1200-Hz FM carrier modulated by the non-audio signal has replaced the microphone signal, while using the REC operating mode of the MP3 player, which triggers the voice recording function. The signal recovery was carried out by a PLL-based FM demodulator whose input is the FM signal captured in the coil leads of the MP3 player's earphone. Sinusoidal and electrocardiogram signals have been used in the system evaluation. Although the quality of low frequency signals needs improvement, overall the results indicate the viability of the proposal. Suggestions are made for improvements and extensions of the work.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)