984 resultados para super-orbital re-entry
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OBJECTIVES: Gender differences in psychotic disorder have been observed in terms of illness onset and course; however, past research has been limited by inconsistencies between studies and the lack of epidemiological representative of samples assessed. Thus, the aim of this study was to elucidate gender differences in a treated epidemiological sample of patients with first episode psychosis (FEP). METHODS: A medical file audit was used to collect data on premorbid, entry, treatment and 18-month outcome characteristics of 661 FEP consecutive patients treated at the Early Psychosis Prevention and Intervention Centre (EPPIC), Melbourne, Australia. RESULTS: Prior to onset of psychosis, females were more likely to have a history of suicide attempts (p=.011) and depression (p=.001). At service entry, females were more likely to have depressive symptoms (p=.007). Conversely, males had marked substance use problems that were evident prior to admission (p<.001) and persisted through treatment (p<.001). At service entry, males also experienced more severe psychopathology (p<.001) and lower levels of functioning (GAF, p=.008; unemployment/not studying p=.004; living with family, p=.003). Treatment non-compliance (p<.001) and frequent hospitalisations (p=.047) were also common for males with FEP. At service discharge males had significantly lower levels of functioning (GAF, p=.008; unemployment/not studying p=.040; living with family, p=.001) compared to females with FEP. CONCLUSIONS: Gender differences are evident in illness course of patients with FEP, particularly with respect to past history of psychopathology and functioning at presentation and at service discharge. Strategies to deal with these gender differences need to be considered in early intervention programs.
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Desenvolupament d'un videojoc per a Android i un videojoc per a navegador; tots dos relacionats amb la prctica de les matemtiques.
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The performance of the SAOP potential for the calculation of NMR chemical shifts was evaluated. SAOP results show considerable improvement with respect to previous potentials, like VWN or BP86, at least for the carbon, nitrogen, oxygen, and fluorine chemical shifts. Furthermore, a few NMR calculations carried out on third period atoms (S, P, and Cl) improved when using the SAOP potential
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The signaling pathway that regulates glucose-stimulated insulin secretion depends on glucose metabolism, which is itself controlled by glucokinase. In a recent issue of Cell, show that altering N-glycosylation of the GLUT2 glucose transporter prevents its anchoring and retention at the cell surface; this impairs glucose uptake and insulin secretion.
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O objetivo deste artigo foi apresentar as bases para a construo de uma ferramenta re-leitora do Processo Sade-doena, por meio da relao dialgica entre categorias sociais e as variveis funcionais, contidas no instrumento CIPESC de Curitiba. Ancorou-se nos marcos conceituais apresentados na Teoria da Interveno Prxica da Enfermagem em Sade Coletiva. A ferramenta constituiu-se de um modelo analtico de apoio tomada de deciso, pretendendo o desenvolvimento de data warehouse. Os dados do pronturio eletrnico do paciente, relacionados s categorias: Necessidade, Classe Social, Gnero, Etnia e Gerao, desvelam a face social e atribuem vulnerabilidade aos grupos sociais homogneos. Foram visualizados quatro graus de vulnerabilidade, qualificados por 11 marcadores. O estudo remeteu reflexo de que as desigualdades reproduzem-se ao longo do tempo e transformam grupos em alvos de imobilidade social. Embora existam lacunas para visualizao das categorias sociais, o instrumento permitiu visualizar a face coletiva de famlias e grupos sociais.
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Ecrit par le copiste Bertrand (f. 170v).
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In rodents and nonhuman primates subjected to spinal cord lesion, neutralizing the neurite growth inhibitor Nogo-A has been shown to promote regenerative axonal sprouting and functional recovery. The goal of the present report was to re-examine the data on the recovery of the primate manual dexterity using refined behavioral analyses and further statistical assessments, representing secondary outcome measures from the same manual dexterity test. Thirteen adult monkeys were studied; seven received an anti-Nogo-A antibody whereas a control antibody was infused into the other monkeys. Monkeys were trained to perform the modified Brinkman board task requiring opposition of index finger and thumb to grasp food pellets placed in vertically and horizontally oriented slots. Two parameters were quantified before and following spinal cord injury: (i) the standard 'score' as defined by the number of pellets retrieved within 30 s from the two types of slots; (ii) the newly introduced 'contact time' as defined by the duration of digit contact with the food pellet before successful retrieval. After lesion the hand was severely impaired in all monkeys; this was followed by progressive functional recovery. Remarkably, anti-Nogo-A antibody-treated monkeys recovered faster and significantly better than control antibody-treated monkeys, considering both the score for vertical and horizontal slots (Mann-Whitney test: P = 0.05 and 0.035, respectively) and the contact time (P = 0.008 and 0.005, respectively). Detailed analysis of the lesions excluded the possibility that this conclusion may have been caused by differences in lesion properties between the two groups of monkeys.
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We analyze the entry of a new product into a vertically differentiated market in which an entrant and an incumbent compete in prices. Here the entry-deterrence strategies of the incumbent firm rely on limit qualities. With a sequential choice of quality, a quality-dependent marginal production cost, and a fixed entry cost, we relate the entry-quality decision and the entry-deterrence strategies to the level of entry cost and the degree of consumer heterogeneity. Quality-dependent marginal production costs in the model entail the possibility of inferior-quality entry as well as an incumbents aggressive entry-deterrence strategies of increasing its quality level toward potential entry. Welfare evaluation confirms that social welfare is not necessarily improved when entry is encouraged rather than deterred.
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chelle(s) : 1:100 000
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[Traditions. Afrique. Madagascar]
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Cf. notice du ms. par Leroquais, Sacramentaires, II, 180-183 n 366. Les incipit des proses ont t relevs dans la table des incipit. F. 1-6v Calendrier de Paris : 3 janv., en rouge, Genovefe virg. IX lc. (1); 22 avr., Inventio corporis s. Dyonisii sociorumque ejus. Oportune virg. semid. (2v); 28 mai, en rouge, Germani ep. Parisiensis semid. Carauni mart. memoria (3); 25juin, en violet, Translatio s. Eligii ep. (3v); en violet, In prima dominica hujus mensis [augusti] fit d. de cruce [rception Notre-Dame d'un fragment de la vraie Croix] (4v); 9 oct., en rouge, Dyonisii sociorumque ejus duplex (5v); 28 oct., Germani ep. Translatio s. Genovefe virg. mart. memoria (5v); 3 nov. Marcelli ep. Parisiensis dupl.; 13 nov., Gendulphi ep. et conf. [Parisiensis] dupl.; 26 nov., en violet, Genovefe virg. de miraculo [ardentium] IX lc. (6); 4 dc., Susceptio capillorum b. Marie et capitis b. Dyonisii in ecclesia Parisiensi (6v). Le calendrier ne contient pas la fte de s. Louis au 25 aot (tablie en 1298) ni au 17 mai la translation du chef de s. Louis la Sainte-Chapelle (en 1306); Ajout du XIVe s. au 30 avr., Eutropii mart. et conf. [culte tabli Paris en 1296] (2v); cf. Leroquais, Brviaires, I, CXII-CXIII, Tableau chronologique des ftes parisiennes. Au dbut de chaque mois, vers sur les jours gyptiaques (d. Hennig, Traditio, XI (1955), 84 III), sauf celui de janvier (1) qui correspond au premier vers de la srie d. par Riese (Anthol. lat., I2 (1906), 680a); la fin de fvrier, vers sur l'anne bissextile : Byssextum sexte martis tenuere kalende...; cf. ms. Latin 3162, f. 102 (1v); la fin de mars, vers sur la date de Pques : Post martis nonas ubi sit nova luna requiras... (2); Notations astrologiques et de comput, passim. F. 7-353v Temporal, avec parties chantes notes. Incomplet du dbut par la perte du premier f., il commence dans la prose du premier dimanche de l'Avent : ... [eterna indefici]ens mundi vita... (7). remarquer : dominica IIIa [in Adventu] more ecclesie Parisiensis (24v); Crmonie des Cendres avec rubriques liturgiques (62v-66v); Dimanche des Rameaux, congregatis processionibus conventualibus in ecclesia B. Marie, capiceriis portantibus capsam et tribus clericis in albis paratis tres textus, exitur de ecclesia nichil cantando et sic eundum est ad ecclesiam Sancte Genovefe de Monte... (147); cf. Leroquais, 181; Dans l'vangile des Rameaux, le Christ est dsign par la lettre L, le narrateur par la lettre C et les autres par la lettre S (153-158); dans les autres vangiles de la Passion (162-186 passim), ces lettres suscrites ont t effaces et remplaces la mine de plomb de faon sporadique, le Christ tant alors dsign par une croix; Oremus pro papa nostro N... (186v); ... pro christianissimo rege nostro N... (187); Parmi les litanies, s.Stephane... s. Dyonisi... (191v)..., s. Lucane... s. Justine... s. Gendulphe... s. Germane... (199)..., s. Genovefa... (201v). Incipit ordo misse. Sacerdos primo induat se rocheto dicens : Actiones nostras... (203v-206); pour les rubriques liturgiques, cf. Leroquais, 181; Prfaces notes : Incipiunt prefationes... (206-210); Canon de la messe (210-213); pour les rubriques liturgiques, cf. Leroquais, 182; In die Re[sur]rectionis (214); In die sancto [Pentecostes] (262v); [De sancta Trinitate] (280v); Dominica XXVa (348v); In dedicatione ecclesie (350-353v). La fte du Saint-Sacrement ne figure pas. F. 354-496v Sanctoral, avec parties chantes notes. noter parmi les saints parisiens : 3 janv., S. Genovefe virg. (373v); 22 avr., Inventio corporis s. Dyonisii, Rustici et Eleuterii (398v); 28 mai, S. Germani ep. Parisiensis (407v); 10 juin, S. Landerici Parisiensis ep. (410); 26 juill., In translatione s. Marcelli (432); 11aot, De receptione s. corone... (443v); , 4 oct., Auree virg. [abb. Parisiis] (480); 9 oct., In die [s. Dyonisii], avec octave (481v); 28oct., In translatione s. Genovefe (487); 3nov., S. Marcelli Parisiensis ep., avec octave (489v); 26 nov., S. Genovefe de miraculo ardentium (495); De s. Gendulpho. Prosa (495). F. 497-541 Commun des saints, avec pices chantes notes. F. 541-559 Messes votives, sans parties notes l'exception de la messe des morts (551v-556). Aux ff. 546v-547, en marge de la messe pro amico, deux additions d'une criture cursive de la fin du XIVe s. prcisent : ducem nostrum et duxissem ejusque prolem. Prires diverses (556-559). F. 559-563 Rituel de mariage. Incipit ordo ad sponsam benedicendam. Cum venerint ante valvas ecclesie sponsus et sponsa, accinctus sacerdos alba et stola... auxilium et argentum super scutum positum benedicat dicens : Manda Deus... Tunc aspergatur aqua benedicta et thurificetur et sponsus et sponsa; quo facto sacerdos dicat : Bones genz nos avons faiz les bans III foiz de ces II genz et encore les faison nous, que se il i a nul ne nule qui sache enpeschement par quoi l'un ne puisse avoir l'autre par loi de mariage, si le die. Et re[spon]dent assistentes : Nous ni savons se bien non. Quo audito, accipiat sacerdos manum dexteram sponse et ponat in dextera manu sponsi et dicat... nominandos eos : Vos Marie et vos Jeham vous prometez, fianciez et jurez l'un l'autre garder la foi et la loiaut du mariage... Tunc sacerdos tradat anulum sponso et sponsus autem per manum sacerdotis primo in police sponse... dicens... : Marie de cest annel t'espous et de mon cors t'ennor et de douaire qui est devisiez entre mes amis et les tiens. In nomine... Secundo in indice dicens... Tercio in medio dicens : Et Spiritus sancti. Amen... Postea sacerdos extensa manu super illos dicat orationes... Tunc sacerdos centus [sic] sponsum per manum dexteram et sponsam et introducat eos in ecclesiam... (559-559bis); Messe de mariage, comportant deux prfaces notes : Deinde celebratur missa... (559bis-562v); pour les rubriques liturgiques, cf. Leroquais, 183. Missa celebrata, recedant sponsus et sponsa et, ipsis stantibus ante hostium domus illorum presentibus pane et vinum [sic], faciat sacerdos benedictionem super panem dicens : Benedic Domine creaturam... Tunc sponsus mordet in pane, postea sponsa. Item benedictio super vinum... Tunc sponsus bibat, postea sponsa. Quo facto introducit eos sacerdos per manum in domum... Item in sero benedictio thalami... Tunc turificet thalamum, postea sponsum et sponsam sedentes vel jacentes in lecto suo benedicat dicens : Benedic Domine adulescentulos... (562v-563) (d. avec variantes par E. Martne, De antiquis Ecclesiae ritibus, II, 374-376, d'aprs le ms. Latin 859A); mme ordo dans le ms. NAL 2649, f. 333-336. F. 563-565v Exorcisme de l'eau et du sel (563-564v). Pro Terra sancta (564v-565). Pro rege nostro (565). Benedictio pere et baculi peregrinorum (565-565v). Benedictio crucis... Benedictio novorum fructuum... Benedictio panis (565v).
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Pharmacological treatment of hypertension is effective in preventing cardiovascular and renal complications. Calcium antagonists (CAs) and blockers of the renin-angiotensin system [angiotensin-converting enzyme (ACE) inhibitors and angiotensin II antagonists (ARBs)] are widely used today to initiate antihypertensive treatment but, when given as monotherapy, do not suffice in most patients to normalise blood pressure (BP). Combining a CA and either an ACE-inhibitor or an ARB considerably increases the antihypertensive efficacy, but not at the expense of a deterioration of tolerability. Several fixed-dose combinations are available (CA + ACE-inhibitors: amlodipine + benazepril, felodipine + ramipril, verapamil + trandolapril; CA + ARB: amlodipine + valsartan). They are expected not only to improve BP control, but also to facilitate long-term adherence with antihypertensive therapy, thereby providing maximal protection against the cardiovascular and renal damage caused by high BP.
