Análise de estruturas reticuladas utilizando o software excel pelo método dos elementos finitos

Pós-graduação em Engenharia Mecânica - FEG

Critérios de qualidade em artigos e periódicos científicos: da mídia impressa à eletrônica

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação do desempenho das propriedades mecânicas de concretos self compacting elaborados com diferentes tipos de cimentos submetidos à cura térmica

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Understanding the Function of Conserved Variations in the Catalytic Loops of Fungal Glycoside Hydrolase Family 12

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Fatores que interferem nas taxas de recuperação embrionária em éguas

The success in implementing an embryo transfer program derives from many factors. The embryo recovery rate is one of the most important factors, and allows the transfer to the recipient mare. This rate comes from a group of elements such as donor´s characteristics, collection date, reproductive management, semen quality, technician skill. Mainly because of the great importance of this direct interference on the results of an embryo recovery program, this study aimed to review the factors involved in embryo recovery rates in donor mares during an embryo transfer, suggesting some ways of improving these results

Aplicação e análise da utilização do software Eberick em um projeto residencial popular

Due to new technologies in civil engineering and the competition of the market, the demand for computer programs for the elaboration of structural projects of reinforced concrete is raising in a quick and efficient manner. This paper presents a study based on Eberick, a structural calculation software, and this software was applied to a low cost residence project. By performing structural calculation manually, it is possible to compare and analyze the criteria that Eberick uses for the design and detailing of structural elements like columns, beams and slabs. As the software functionality becomes clear, the engineer will use it careful and safely, exploring all of its resources and advantages

Pontes de madeira para pequenos vãos para situações emergenciais

In Brazil there are many cases of cities that suffer from flooding. It often destroys much of the structure of the city, and isolates many families. Relying on emergency measures for these cases and similar cases is of utmost importance. This paper proposes the development of a project of a timber bridge that can be used in emergency situations such as occurs in situations of floods and especially on side roads. It is considered one type of structural bridge which has, among other characteristics, an easy transportation and assembly of the elements. The development is carried out, at this early stage of the project, only about the verification and sizing of structural elements of the superstructure of the bridge. For this purpose, it relies on computer programs, and fundamentally on PCFrame Visual Taco. The first allows you to model the structure and determine the efforts of calculating the elements, and the second one assists at the scaling and the verifications in accordance with the Brazilian technical standards for timber bridges. The wood used in the project comes from the tree Eucalyptus saligna, which is easy to acquaint and manipulate and comes from the region Vale do Paraíba. The bridge in this case of application should have the characteristics mentioned below: short execution time, simplicity of structure and an assembly of a relatively low cost

A Sancta Sapientia Medieval: enigma e mistério no teatro cristão de Rosvita de Ganderseheim

Within the scope of Literary Studies, theory, criticism, and historiography about the literature produced in the Middle Ages developed considerably from 1940 on, with the works of Ernst Curtius, Mikhail Bakhtin, and Erich Auerbach. In spite of the progress made, some specific aspects remain in the shadow, with incursions which were punctual though meaningful: that is the case of the critic fortunes about women‟s literary production in that period. Rosvita was a canoness and lived in the Benedictine convent of Gandersheim (Germany), in the 10th century A.D. Coming under Terence‟s influence, she wrote theater plays in Latin in which she figuratively presented theological issues in order to spread the Christian doctrine. The martyrdom issue deserved to be put in relief and was the focal point of the play Wisdom, which took place at the time of the Roman emperor Adrian. This paper analyzes that dramatic text discussing, at the end, how the categories of symbol, enigma, allegory, and mystery are organized by the author as expressive resources and structural elements.

Os desenhos da cidade observada: uma reflexão singular

How are teachers Cartoons observation Architecture Schools in several decades, the idea was to try and explain firsthand the look and fundamental elements of drawings to the Architect. We start looking through the design of: 1 A projective gaze: the invisible is made visible by interactivity and space and time are perceived by the distance that look place between them; 2nd In bidirectional contamination: the object fills the subject, double-hand, bringing the tactile qualities of architecture in continuous resonance, 3rd Strangeness by slow look: draw as perceptual expansion strategy; 4 Articulation of the structural elements of the design while similar language to architecture and city through the selection of appropriate signs and codes, exclusive and singular.

Aboutness em Análise Documental de textos literários infanto-juvenis: perspectivas para o aprimoramento da representação de conteúdo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Considerações sobre a armadura transversal de pilares de concreto armado

There are regulations that establish conditions and enable the design of armor columns. The NBR 6118 features statements relating to the transverse reinforcement as spacing, reinforcement diameters provision in structural elements and others. However, the norm in force does not provide an explicit methodology for the design of stirrups in different situations. We do not propose even a calculation model for this equipment and provides normative considerations for maximum or minimum values of spacings and armor in diameter. It is noteworthy that the classical references also do not provide a calculation routine sizing of transverse reinforcement and only makes the checks as the normative conditions for the given data. Based on this assumption and the problems that may occur in sizing error, both for spacing and for the proposal of the stirrup diameter, this study demonstrates that armor calculation method already established in the literature and then through an intuitive tool and available develops a spreadsheet based on this calculation routine. It takes as reference the one developed by Emil Moersch (1902) and the calculation model proposed by BUFFONI E SILVA (2006). Finally the paper presents a rational design of shear reinforcement and confronts these values with some numerical examples to show its truth

Considerações sobre a armadura transversal de pilares de concreto armado

There are regulations that establish conditions and enable the design of armor columns. The NBR 6118 features statements relating to the transverse reinforcement as spacing, reinforcement diameters provision in structural elements and others. However, the norm in force does not provide an explicit methodology for the design of stirrups in different situations. We do not propose even a calculation model for this equipment and provides normative considerations for maximum or minimum values of spacings and armor in diameter. It is noteworthy that the classical references also do not provide a calculation routine sizing of transverse reinforcement and only makes the checks as the normative conditions for the given data. Based on this assumption and the problems that may occur in sizing error, both for spacing and for the proposal of the stirrup diameter, this study demonstrates that armor calculation method already established in the literature and then through an intuitive tool and available develops a spreadsheet based on this calculation routine. It takes as reference the one developed by Emil Moersch (1902) and the calculation model proposed by BUFFONI E SILVA (2006). Finally the paper presents a rational design of shear reinforcement and confronts these values with some numerical examples to show its truth

Natural intracellular peptides can modulate the interactions of mouse brain proteins and thimet oligopeptidase with 14-3-3e and calmodulin

Protein interactions are crucial for most cellular process. Thus, rationally designed peptides that act as competitive assembly inhibitors of protein interactions by mimicking specific, determined structural elements have been extensively used in clinical and basic research. Recently, mammalian cells have been shown to contain a large number of intracellular peptides of unknown function. Here, we investigate the role of several of these natural intracellular peptides as putative modulators of protein interactions that are related to Ca2+-calmodulin (CaM) and 14-3-3 epsilon, which are proteins that are related to the spatial organization of signal transduction within cells. At concentrations of 1-50 mu M, most of the peptides that are investigated in this study modulate the interactions of CaM and 14-3-3 epsilon with proteins from the mouse brain cytoplasm or recombinant thimet oligopeptidase (EP24.15) in vitro, as measured by surface plasmon resonance. One of these peptides (VFDVELL; VFD-7) increases the cytosolic Ca2+ concentration in a dose-dependent manner but only if introduced into HEK293 cells, which suggests a wide biological function of this peptide. Therefore, it is exciting to suggest that natural intracellular peptides are novel modulators of protein interactions and have biological functions within cells.

Adhesion of Trypanosoma cruzi Trypomastigotes to Fibronectin or Laminin Modifies Tubulin and Paraflagellar Rod Protein Phosphorylation

Background: The unicellular parasite Trypanosoma cruzi is the causative agent of Chagas disease in humans. Adherence of the infective stage to elements of the extracellular matrix (ECM), as laminin and fibronectin, is an essential step in host cell invasion. Although members of the gp85/TS, as Tc85, were identified as laminin and fibronectin ligands, the signaling events triggered on the parasite upon binding to these molecules are largely unexplored. Methodology/Principal Findings: Viable infective parasites were incubated with laminin, fibronectin or bovine serum albumin for different periods of time and the proteins were separated by bidimensional gels. The phosphoproteins were envisaged by specific staining and the spots showing phosphorylation levels significantly different from the control were excised and identified by MS/MS. The results of interest were confirmed by immunoblotting or immunoprecipitation and the localization of proteins in the parasite was determined by immunofluorescence. Using a host cell-free system, our data indicate that the phosphorylation contents of T. cruzi proteins encompassing different cellular functions are modified upon incubation of the parasite with fibronectin or laminin. Conclusions/Significance: Herein it is shown, for the first time, that paraflagellar rod proteins and alpha-tubulin, major structural elements of the parasite cytoskeleton, are predominantly dephosphorylated during the process, probably involving the ERK1/2 pathway. It is well established that T. cruzi binds to ECM elements during the cell infection process. The fact that laminin and fibronectin induce predominantly dephosphorylation of the main cytoskeletal proteins of the parasite suggests a possible correlation between cytoskeletal modifications and the ability of the parasite to internalize into host cells.

Considerações de interesse sobre a avaliação em laboratório de elementos estruturais em situação de incêndio: contribuições à revisão da NBR 5628:2001

Existe um crescente interesse sobre a pesquisa sobre a segurança das estruturas em situação de incêndio no Brasil, mas ainda existem aspectos que carecem de discussão. A simulação e avaliação em laboratório de elementos estruturais em situação de incêndio é um desses aspectos, principalmente no que diz respeito à metodologia de ensaio. A norma técnica brasileira NBR 5628:2001 necessita de revisão com vistas à adaptação das metodologias internacionais à realidade brasileira ou, até mesmo, à definição de novas metodologias que considerem variáveis relevantes para o contexto local. Este trabalho apresenta um ponto de partida para essas discussões e reúne os parâmetros que norteiam os procedimentos metodológicos para a avaliação de elementos estruturais, em escala natural, com carga, e em situação de incêndio. Parâmetros de interesse como dimensões mínimas dos elementos, taxas de elevação de temperatura com o tempo, infraestrutura para o ensaio, instrumentação dos elementos estruturais, entre outros, são avaliados à luz da normalização nacional e internacional vigente. Espera-se que este trabalho forneça subsídios para a futura revisão da NBR 5628:2001 e estimule pesquisadores brasileiros a ingressar nessa nova e árdua linha de pesquisa.