999 resultados para métodos de tratamento
Resumo:
As arterial hypertension can be diagnosed by different methods, among which are the traditional auscultatory instrument and the automated oscillometric monitor, the aim of this study was to compare the performance of these instruments, to evaluate the reliability of the digital oscillometer. The sample consisted of 40 patients under dental treatment, whose blood pressure measurements were recorded. The measurements of systolic and diastolic blood pressures were evaluated in terms of their intraclass correlation coefficients (r). For systolic blood pressure, an excellent level of agreement was found between the instruments, with r=0.93, and for diastolic blood pressure, there was a good level of agreement (r=0.75). It was concluded, from the excellent agreement for systolic blood pressure, that the oscillometric monitor can be recommended for the monitoring of the variations of that pressure in the same individual, while the good agreement obtained in the determination of the diastolic blood pressure indicates that the oscillometric method is reliable. However, new studies need to be carried out for a better understanding of the disagreements that can occur in the diastolic pressure results.
Resumo:
Darunavir is a protease inhibitor used in the treatment of HIV infection. It is a pillar of the drug cocktail for patients diagnosed with the virus. Quality control in the pharmaceutical industry, to verify the content of active substance and study the physicochemical characteristics of the drug, is essential to ensure final product quality. Until now, standardized methods for the analysis of darunavir have not been available in official compendia. This justifies new research, to develop and validate analytical methods, as well as physicochemical and pharmaceutical analysis for this drug, both as a raw material and a finished product. Thus, in this study, (a) the average weight of darunavir tablets and (b) the melting point of the pure drug were determined, and the following analytical techniques were performed: (c) thin-layer chromatography, (d) ultraviolet spectroscopy, (e) infrared spectroscopy and (f) high performance liquid chromatography. By developing the above techniques, it is possible to make a qualitative assessment of the quality of darunavir tablets.
Resumo:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Resumo:
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Resumo:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Resumo:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Resumo:
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Resumo:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Resumo:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Resumo:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Resumo:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Resumo:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Resumo:
Pós-graduação em Engenharia e Ciência de Alimentos - IBILCE
Resumo:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Resumo:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)