Exploring the factor structure of neurocognitive measures in older individuals

Here we focus on factor analysis from a best practices point of view, by investigating the factor structure of neuropsychological tests and using the results obtained to illustrate on choosing a reasonable solution. The sample (n=1051 individuals) was randomly divided into two groups: one for exploratory factor analysis (EFA) and principal component analysis (PCA), to investigate the number of factors underlying the neurocognitive variables; the second to test the "best fit" model via confirmatory factor analysis (CFA). For the exploratory step, three extraction (maximum likelihood, principal axis factoring and principal components) and two rotation (orthogonal and oblique) methods were used. The analysis methodology allowed exploring how different cognitive/psychological tests correlated/discriminated between dimensions, indicating that to capture latent structures in similar sample sizes and measures, with approximately normal data distribution, reflective models with oblimin rotation might prove the most adequate.

Algumas considerações sobre o princípio da culpa enquanto factor de autonomização do Direito das Contra-ordenações

Dissertação de mestrado em Direito Judiciário

Synthetic biology approaches to shape bacteriophages towards Pseudomonas aeruginosa biofilm control

Dissertation for Ph.D. degree in Biomedical Engineering.

Desarrollo de una técnica de detección rápida y precisa de preñez en cerdos. Segunda etapa: Purificación de factor precoz de preñez y desarrollo de un radioinmunoensayo

Una de las principales causas de pérdida reproductiva en condiciones normales, es la mortalidad embrionaria basal. Por lo tanto, estaría ampliamente justificado el diseño de experiencias que nos permitan encontrar las causas de las pérdidas y detectar la preñez tan precozmente, como fuere posible. Las causas de las pérdidas embrionarias en muchos casos se relacionan con fallas en las señales del embrión dirigidas a la madre con el fin de establecer inmunotolerancia, fenómeno imprescindible para la sobrevida del embrión porque modifica la respuesta inmune de modo favorable para éste. La inmunomodulación es ejercida por sustancias de naturaleza proteica detectadas durante la gestación. Entre estas se encuentra el Factor Precoz de Preñez (EPF). Durante la preñez, el EPF tiene dos fuentes de producción: una materna y otra embrionaria. El EPF materno, también llamado temprano, se produce durante los períodos pre y periimplantacional y persiste hasta el último tercio de la preñez. Hasta el presente, la única técnica desarrollada para la detección del EPF, es un ensayo in vitro propuesto por Morton que mide de manera indirecta la actividad del factor. Dicha técnica se basa en la capacidad que tiene el EPF de potenciar la acción de un suero antilinfocitario (SAL), para inhibir la formación de rosetas entre linfocitos T y eritrocitos heterólogos en presencia de complemento. Esta técnica es efectiva pero muy compleja para realizarse rutinariamente en el laboratorio. De todo lo expuesto surge claramente la necesidad del aislamiento y purificación del EPF, lo que permitiría desarrollar metodologías inmunológicas aplicables para el diagnóstico de rutina de detección de preñez en cerdos y un notable adelanto en el estudio de alguno de los factores que afectan los sucesos de concepción y el curso de preñez, momentos claves en la fisiología reproductiva. Objetivos Generales - Desarrollar una técnica de detección rápida y precisa del Factor Precoz de Preñez (EPF) en cerdos. Objetivos Específicos - Aislar, purificar y caracterizar al Factor Precoz de Preñez (EPF) a partir de suero y placenta de cerdas gestantes. - Obtener y valorar un antisuero policlonal anti-EPF en conejos a partir de la fracción purificada con mayor índice de actividad EPF.

Capturing the essence of shape of polygonal meshes

Polygonal meshes, essential shape representation, feature detection, external skeleton, mesh decimation, progrssive meshes, silhouettes, hidden line removal, non-photorealistic rendering, OpenNPAR

Active shape structural model

Shape model, deformable models, structural models, biometry, content based image retrieval, sketches

Jacob - an activity regulated morphogenetic factor for synapto-dendritic cytoarchitecture

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2008

Cross-talk of protein kinase B (PKB/Akt) with the transcription factor NFAT and the Src kinase Fyn in T lymphocytes

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2010

Modulation of [My]-opioid receptor signal transduction and endocytosis by ADP-ribosylation factor proteins

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2010

Konstruktion einer nicht-IGF-bindenden Insulin-like Growth Factor Binding Protein-2-Variante und Untersuchung ihrer Wirkung auf das Tumorzellwachstum

Magdeburg, Univ., Medizin. Fakultät, Diss., 2008

Regulation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-[kappa]B) by protein Kinase C theta (PKC-[theta]) and cylindromatosis (CYLD) in murine listeriosis and toxoplasmosis

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2013

Effects of grain shape on packing and dilatancy of sheared granular materials

Aus: Soft matter, Vol. 10.2014, H. 28, S. 5157 - 5167

The effectiveness of methods of shape analysis / Cliff A. Lemen.

n.s. no.15(1983)

Width-weight relationship and condition factor of Ucides cordatus (Crustacea, Decapoda, Ucididae) at tropical mangroves of Northeast Brazil

The present contribution aims at evaluating the carapace width vs. humid weight relationship and the condition factor of Ucides cordatus (Linnaeus, 1763), in the mangrove forests of the Ariquindá and Mamucabas rivers, state of Pernambuco, Brazil. These two close areas present similar characteristics of vegetation and substrate, but exhibit different degrees of environmental conservation: the Ariquindá River is the preserved area, considered one of the last non-polluted of Pernambuco, while the Mamucabas River suffers impacts from damming, deforestation and deposition of waste. A total of 1,298 individuals of U. cordatus were collected. Males were larger and heavier than females, what is commonly observed in Brachyura. Ucides cordatus showed allometric negative growth (p < 0.05), which is probably related to the dilatation that this species develops in the lateral of the carapace, which stores six pairs of gills. The values of b were within the limit established for aquatic organisms. Despite of the condition factor being considered an important feature to confirm the reproductive period, since it varies with cyclic activities, in the present study it was not correlated to the abundance of ovigerous females. However, it was considered a good parameter to evaluate environmental impacts, being significantly lower at the impacted area.