908 resultados para Risco-Brasil


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Pós-graduação em Fisiopatologia em Clínica Médica - FMB

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Objetivo:O objetivo deste estudo foi investigar o fenótipo do HLA em pacientes com contratura de Dupuytren (CD) para verificar a correlação desses alelos com os fatores de risco para o desenvolvimento da CD na população brasileira.Métodos:Este foi um estudo de caso-controle de 25 pacientes com CD e 443 indivíduos saudáveis sem histórico de doenças associadas ao HLA. As tipagens classe I e classe II do HLA foram feitas utilizando o método iniciador de sequências específicas da reação em cadeia da polimerase.Resultados:O fenótipo HLA-B*18 foi observado em 32% dos pacientes e 10,5% do grupo controle. Contudo, os valores de p não permaneceram significativos após correção.Discussão:Apesar de termos observado um aumento na tendência de os pacientes com CD terem o alelo HLA-B*18, os resultados não foram estatisticamente significativos após correção. Esse alelo foi maior em pacientes de etnia italiana e/ou espanhola, locais com frequências superiores a 18% e 14%, respectivamente. São necessárias investigações adicionais com uma coorte maior de pacientes com CD para confirmar o possível papel do HLA nessa doença.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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In the last few decades, Brazil has experienced an accelerated urbanization process in which many cities have grown in a disorderly way occupying environmentally fragile areas unsuitable for habitation. Anthropogenic actions such as high levels of impermeable soil, structural changes in watercourses, lack of riparian vegetation, illegal presence of trash and rubbish along the river banks added to irregular settlements in floodplains result in the rise of high risk areas. When accompanied by intense and prolonged rainfall phenomena, those areas have been the scenery of serious accidents such as floods. This study aims to classify the level of the risk of floods in the neighborhood of Jardim Inocoop, in the town of Rio Claro, São Paulo countryside, Brazil. One of the main technical support to tackle this issue is the identification and classification of the risks. In order to classify the risk level of flood in this case study, the methodology adopted was developed by the Ministry of Cities and Technology Research Institute, and take into account the arrangement of the hydrological scenario, vulnerability of households and dangerous process according to the distance of the houses from the axis of drainage. Therefore, the risk levels adopted to classify are listed below: very high (MA), high risk (A), moderate (M) and low risk (B). In conclusion, it is imperative to develop prevention plans in order to avoid or to minimize the damages caused by natural disasters. Therefore, the zoning of the risk sceneries remains as an important issue once it helps to identify the areas with high level risk of flood. Consequently, the occupation must be regulated where there is low or absent risk and it must be often forbidden where the high risk of flood is detected. Thus, the present study remains as an attempt to notify the risk of floods through its spatialization on a map, remainig...(Complete abstract click electronic access below)

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The disaster natural disaster stand as one of the greatest challenges of urban man. Cities are built and modeled as a function of economic and political issues, without respecting environmental characteristics. So it is possible to see through the data of the National Civil Defence large number of disasters occurring in Brazilian cities in the years 2009 to 2011, and in all were reported over 5000 occurrences of natural disasters over the years. The Brazilian public policy failures show up in issues of urban planning where to admit the allocation of people in inappropriate areas. Another issue to be considered is the non-response of the population to civil defense warnings, people often prefer to risk staying in high-risk areas for fear of being robbed while they are away, and end up not serving the notices given by the Civil Defense, increase thus the number of victims when in fact the weather event triggers natural disasters one

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Tuberculosis and brucellosis are important diseases in national scenario, as they affect national cattle and can be transmitted to human, as they are zoonosis. The transmission risk increases mostly for those who have strict contact with animals, as is this case of slaughterhouse workers. This paper presents a bibliographic review of data referent to both diseases occurring in bovine slaughterhouse workers in Brazil, characterizing as occupational zoonosis diseases. We still have few data available of this subject, what raise difficulties to know the real incidence of both diseases in national cattle and in people who work in contact with animals, and most of the time are not instructed to the risk that they are exposed and how to prevent it. It’s important to know which is the situation of both diseases so that prevention and even eradication measures can be taken, as we know the Veterinary has an essential function in this matter, protecting animal health as much as protecting national public health

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Proteins of animal origin are among the most consumed foods in the world, this scenario highlights the pig production, providing much of the daily protein intake worldwide. Brazil has significant numbers in the production and export of pork to stand among the first in the world marker. Several diseases such as brucellosis, can configure a threat to this sector. Brucellosis in pigs is an important disease and zoonosis once it is the cause of great economic losses by making the species vulnerable to sanitary barriers as well as putting at risk the health of attendants of farms, slaughterhouses employees and consumers. Pigs slaughtered in slaughterhouses approved by competent organs guarentee the safety of employees, in the flowchart of slaughter, and consumers, but illegal slaughterhouses pose risk to public health

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O Brasil caracteriza-se pela pluralidade cultural e religiosa. Muitas religiões, como a Umbanda, o Candomblé e o Espiritismo, utilizam plantas em rituais ou com o intuito de combater doenças. No combate das doenças, as plantas medicinais são utilizadas com base no conhecimento tradicional, muitas vezes distorcido pela sociedade moderna. Portanto, há um risco inerente nesta prática, pois o efeito das plantas medicinais está relacionado à presença de substâncias químicas, geralmente metabólitos secundários, as quais exercem ação farmacológica de forma análoga aos fármacos sintéticos, bem como podem produzir reações adversas ou intoxicação. Além disso, o uso adequado das plantas medicinais envolve conhecimento sobre seu cultivo, colheita/coleta, modo de preparo, posologia e indicação. O objetivo deste trabalho foi realizar uma revisão bibliográfica sobre o uso de plantas medicinais por comunidades religiosas e avaliar o risco de sua utilização com base em evidências científicas. Concluiu-se no trabalho que a maioria das plantas utilizadas está de acordo, totalmente, ou em parte com as indicações de uso na medicina popular ou respaldadas por estudos científicos. Porém, algumas das plantas medicinais utilizadas apresentam alta toxicidade e a indicação de uso de algumas outras, não condiz com estudos científicos ou uso na medicina popular

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The work consists of analyzing the risk management of investments by applying statistical concepts, economic and mathematical models considering the assets on the market on renowned financial institution. The assessment of these risks becomes increasingly interesting in view of minimizing your losses thus maximizing your chances of gains in both markets boom as extreme uncertainty, even with the sudden changes of scenery. Introducing concepts of investment funds, as well as the classification of the types of funds as funds management and equity, its guidelines, the concept of market investment funds. The types of assets comprising the investment funds, their taxation rules beyond the incidents that market widely used by investors and skilled people, both physical and legal, who keep their resources in this modality. With the historical data collected yields of investment funds of the Bank of Brazil, is an accomplished inflation adjustment and calculated the mean and variance for the verification of the model of Markowitz efficient frontier, a method used as investment analysis. This scan is used Matlab to obtain the set (or border) efficient portfolios. Once verified such data, there will be a critique of the Markowitz model as a quadratic programming and more coherent risk measures currently studied as VaR and CVaR minimizing the expected error, approaching our studies of current research. It is found that such studies have much to be explored, since there are many discussions about how effectively measure risk investments such as its characteristic and behavior, using a time series and volatility

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To verify the levels of concentration of some heavy metals in fishes from Sorocaba river (São Paulo, Brazil) and evaluate if this contamination offers health risks to the fishermen, 63 samples of fishes collected from four points along the river were studied for cadmium, lead, chromium, nickel and mercury, with emphasis in this last, since it is the most toxic and most probable as a fish contaminant. Analyzing muscle samples by cold vapor atomic absorption spectrometry it was shown that the fishes are not contaminated. None of the five metals studied were present in prohibitive level and the fishes could be judged secure for human consume. It was also analyzed data from four years of cadmium, lead, chromium, nickel and mercury monitoring made by CETESB, from 1997 to 2000, in water from the main rivers of the State of São Paulo. The study pointed out that the majority of the monitored rivers still present contamination by those metals in a level that requires an improvement of the pollution control actions.

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Pós-graduação em Saúde Coletiva - FMB

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Visceral leishmaniasis (VL) is among the most important vector-borne diseases that occur in Brazil, mainly due to its zoonotic nature. It is currently present in almost all Brazilian territory, and its control is a challenge both for veterinarians and for public health officials. The etiologic agent is Leishmania infantum (syn chagasi), and the main vector in Brazil is Lutzomyia longipalpis. Of all animals identified as reservoirs of VL, the dog is considered the most important domestic reservoir. Although the disease has already been identified in cats, the epidemiological role of this animal species is still unclear. This article presents a brief review of the epidemiological situation of the disease, its mode of transmission, clinical features in dogs and cats as well as possible risk factors associated with the occurrence of the disease in Brazil.

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Pós-graduação em História - FCHS