The licensing of a laboratory for manipulating radionuclides in Brazil

Radionuclides take a major role in guidelines of environmental agencies/national organizations of countries worldwide. In Brazil, CNEN-Comissão Nacional de Energia Nuclear is responsible for managing all subjects related to nuclear energy in the country. Thus, laboratories employing radionuclides for the development of their activities must submit a Radioprotection Plan to CNEN in order to get an operation license. Such plan must indicate that the laboratory is exempt of risks to the people involved and designed to fit all related environmental aspects. This was the case of LABIDRO-Hydrochemical and Isotopes Laboratory that belongs to IGCE-Geosciences and Exact Sciences Institute from UNESP - the University of the State of São Paulo Júlio de Mesquita Filho, located at Rio Claro city, São Paulo State, Brazil. The total monthly activity of the radionuclides utilized during the laboratorial activities held at LABIDRO corresponds to 0.01 μCi. This paper describes all information provided by LABIDRO in order to get the CNEN license. The LABIDRO plan also showed the expected radioactive waste released when the experiments take place and CNEN decided that it fits the guidelines established by Brazilian legislation. Therefore, LABIDRO received its license for utilizing radionuclides, which is valid until September 2016. © 2013 WIT Press.

Exploring the multifactorial nature of autism through computational systems biology: Calcium and the Rho GTPase RAC1 under the spotlight

Autism is a neurodevelopmental disorder characterized by impaired social interaction and communication accompanied with repetitive behavioral patterns and unusual stereotyped interests. Autism is considered a highly heterogeneous disorder with diverse putative causes and associated factors giving rise to variable ranges of symptomatology. Incidence seems to be increasing with time, while the underlying pathophysiological mechanisms remain virtually uncharacterized (or unknown). By systematic review of the literature and a systems biology approach, our aims were to examine the multifactorial nature of autism with its broad range of severity, to ascertain the predominant biological processes, cellular components, and molecular functions integral to the disorder, and finally, to elucidate the most central contributions (genetic and/or environmental) in silico. With this goal, we developed an integrative network model for gene-environment interactions (GENVI model) where calcium (Ca2+) was shown to be its most relevant node. Moreover, considering the present data from our systems biology approach together with the results from the differential gene expression analysis of cerebellar samples from autistic patients, we believe that RAC1, in particular, and the RHO family of GTPases, in general, could play a critical role in the neuropathological events associated with autism. © 2013 Springer Science+Business Media New York.

La protección y el manejo de océanos, mares y zonas costeras en la Plataforma de Tlatelolco sobre Medio Ambiente y Desarrollo: un análisis práctico de sus alcances = The protection and management of oceans, seas and coastal areas under the Tlatelolco Platform on Environment and Development: a practical analysis of its implications

Incluye Bibliografía

Key statistics required under the CARICOM CSME

The approach in this paper is to consider each crucial area of statistics individually, and present and discuss some details highlighting in general where the subregion is with respect to the regular and timely production of the respective area of statistics. The paper concludes with a discussion of some of the major challenges facing statistical development and progress in the subregion.

Critical evaluation of the performance of the ECCM countries under the Agricultural Marketing Protocol (AMP) and the Guaranteed Market Scheme (GMS)

Includes bibliography

Malaysian industrial and trade policies under the new international trading system

Includes bibliography

Industrial and trade policies under the new trading system: toward a comparative analysis between East Asia and Latin America

Includes bibliography

Kinetic study of pyrolysis of castor beans (Ricinuscommunis L) presscake: an alternative use for solid waste arising from the biodiesel production

This work investigated the effects of temperature and of rate of heating on the kinetic parameters of pyrolysis of castor beans presscake, a byproduct generated in the biodiesel production process. Pyrolysis process was investigated by thermogravimetric analysis, and parameters were obtained from nonisothermal experiments. The results obtained from the process of thermal decomposition indicated the elimination of humidity and the decomposition of organic components of the biomass. DTG curves showed that the heating rate affects the temperature of maximum decomposition of the material. Kinetic parameters such as activation energy and pre-exponential factor were obtained by model-free methods proposed by Flynn–Wall–Ozawa (FWO), Kissinger–Akahira–Sunose (KAS), and Kissinger. Experimental results showed that the kinetic parameters values of the FWO and KAS methods display good agreement and can be used to understand the mechanism of degradation of the cake. In a generalized way, the results contribute to better understanding of the processes of biomass pyrolysis.

Trade and Development Nexus: reflections on the performance of trade in goods under the Cariforum-European Union Partnership agreement a Cariforum perspective

Given the asymmetry in the levels of development and capacity which exist between the EU and CARIFORUM States, the architects of the CARIFORUM-European Union (EU) Economic Partnership Agreement (EPA)1 anticipated the need for review and monitoring of the impacts of implementation. Article 5 and other provisions in the Agreement therefore specifically mandate that monitoring be undertaken to ensure that the Agreement benefits a wide cross-section of the population in member countries. The paper seeks to provide a preliminary assessment of the impact of the EPA on CARIFORUM countries. In so doing, it highlights some critical information and implementation gaps and challenges that have emerged during the implementation process. The analysis however, is restricted to goods trade. The services sector will be the subject of a separate report. The paper draws on a combination of quantitative and qualitative analyses. While the paper undertakes a CARIFORUM-wide analysis for the most part, five CARIFORUM member states including Barbados, Dominican Republic, Guyana, Saint Kitts and Nevis and Saint Lucia are examined more closely in some instances. These economies were selected by virtue of economic structure and development constraints, as a representative subset of CARIFORUM, which comprises the CARICOM membership as well as the Dominican Republic.