Interactions membranaires de canaux ioniques artificiels : une étude approfondie par dichroïsme circulaire orienté

Les peptides et les protéines font partie intégrante de l’arsenal dont l’évolution a pourvu les êtres vivants. Plusieurs fonctions essentielles d’un organisme, tel le transport ionique, dépendent d’ailleurs de leur implication. Les protéines-canal sont ubiquitaires chez tous les êtres vivants et pourtant, plusieurs questions non résolues sont soulevées quand on pense à leur mécanisme d’action et plus précisément à la relation qui existe entre leur structure et leur activité. Puisque l’étude des protéines-canal s’avère très complexe et laborieuse, plusieurs ont cherché à les étudier indirectement en développant, par exemple, des modèles synthétiques. Ce mémoire présente une catégorie unique de peptides développés par le groupe Voyer et constitués exclusivement de leucines et de 21-couronne-7-L-phénylalanines. La structure du peptide a été conçue spécialement pour qu’il puisse effectuer du transport ionique membranaire et servir de modèle dans l’étude des protéines-canal. Le peptide a été caractérisé de façon exhaustive au cours des vingt dernières années et les études ont bien établi sa conformation et démontré sa capacité à effectuer du transport membranaire sans, toutefois, lever le voile sur le mécanisme par lequel il opère. Afin d’y voir plus clair et d’en apprendre davantage sur leur mécanisme d’action, les travaux qui sont décrits dans les pages suivantes portent sur la caractérisation par dichroïsme circulaire orienté de la structure et de la topologie membranaire des peptides du groupe Voyer.

A responsabilidade de traduzir o in-traduzível: Jacques Derrida e o desejo de [la] tradução

How should one consider the responsibility of the translator, who is located between the differences of two linguistic systems and in the middle of the various idioms constitute each of the languages involved in the translation? (P. Ottoni). What is the role of the translator in inter-acting with both his/her mother tongue and the idiom of the other? These two questions will be discussed in order to reflect on the responsibility of translating the un-translatable. Two hypotheses orient the paper: 1 - an idiom spoken idiomatically is known as the mother tongue and is not appropriated, so that accommodating the other in one's own language automatically considers his/her idiom (J. Derrida) and 2 - face-to-face with language and its idioms, the translator is trapped in a double (responsibility) bind; faced with something which cannot be translated, he/she is forced to perceive it in another way. In conclusion, how should one consider the responsibility of translating the un-translatable Jacques Derrida?

Práticas escolares e desempenho acadêmico de alunos com TDAH

This article reports the results from the research work which objects the critical and profound study about the ADHD (Attention Deficit/Hyperactivity Disorder) in the courses for teachers' development in College Education, under its various dimensions - social, cultural, pedagogical, biological. The investigation focused on five adults with diagnosis for ADHD. The methodology used was the Case Study, developed from the Oral History as a source of data. The results that were obtained suggest that the study, proposed in the research, may contribute significantly for the teachers to know determining factors of the school performance of students with this disorder, as well as to guide them in the search of partnership with other professionals - doctors and psychologists, for example - when such partnership becomes necessary.

Resposta eletromiografica do musculo iliocostal lombar e abordagem da pressão intradiscal da coluna lombar

Universidade Estadual de Campinas. Faculdade de Educação Física

Recreação e lazer como integrantes de curriculos dos cursos de graduação em educação fisica

Universidade Estadual de Campinas . Faculdade de Educação Física

Recreação e lazer como integrantes dos curriculos dos cursos de graduação em educação fisica

Universidade Estadual de Campinas. Faculdade de Educação Física

Educação fisica, saude coletiva e a luta do MST : reconstruindo relações a partir das violencias

Universidade Estadual de Campinas . Faculdade de Educação Física

Historias infantis : o simbolismo, a ludicidade e a motricidade na ação da educação motora

Universidade Estadual de Campinas . Faculdade de Educação Física

The bubbles or the boiling pot?: an ecosystemic approach to culture, environment and quality of life

For the diagnosis and prognosis of the problems of quality of life, a multidisciplinary ecosystemic approach encompasses four dimensions of being-in-the-world, as donors and recipients: intimate, interactive, social and biophysical. Social, cultural and environmental vulnerabilities are understood and dealt with, in different circumstances of space and time, as the conjugated effect of all dimensions of being-in-the-world, as they induce the events (deficits and assets), cope with consequences (desired or undesired) and contribute for change. Instead of fragmented and reduced representations of reality, diagnosis and prognosis of cultural, educational, environmental and health problems considers the connections (assets) and ruptures (deficits) between the different dimensions, providing a planning model to develop and evaluate research, teaching programmes, public policies and field projects. The methodology is participatory, experiential and reflexive; heuristic-hermeneutic processes unveil cultural and epistemic paradigms that orient subject-object relationships; giving people the opportunity to reflect on their own realities, engage in new experiences and find new ways to live better in a better world. The proposal is a creative model for thought and practice, providing many opportunities for discussion, debate and development of holistic projects integrating different scientific domains (social sciences, psychology, education, philosophy, etc.)

Haptic Stabilization of Posture in Adults With Intellectual Disabilities Using a Nonrigid Tool

This study assessed the effects of haptic information on the postural control systems of individuals with intellectual disabilities (ID), through the use of a nonrigid tool that we call the ""anchor system"" (e.g., ropes attached to graduated weights that rest on the floor). Eleven participants with ID were asked to stand, blindfolded, on a balance beam placed at two heights (10 and 20 cm), for 30 s, while using the anchor system at two weights. The lighter anchor weight appeared to improve the individuals' balance in contrast to a control task condition; therefore, we concluded that haptic sensitivity was more significant in helping to orient the body than was the anchor's mechanical support alone.