Helsinki 18.11.1931

Kirje

Iowa Lottery Action, April 18-29, 2007, vol. 14, no. 7.

Iowa Lottery newsletter for lottery retailers.

Mrs. Hemming Hartikka 18/4 1961

Kirje 18.4.1961

Motor Vehicle Accident Fatalities for the Week Ending, January 18, 2008

Record of the Fatalities for Motor Vehicle Accidents in Iowa per week.

EPI Update, January 18, 2008

Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public Health.

Chefredaktör Rafael Paasio 18.6.1963 Åbo

Kirje

Magister Raoul Palmgren 18.1.1962 Kemi

Kirje

Hina 18.7.1943

Kirje

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

Elevated serum urate concentrations can cause gout, a prevalent and painful inflammatory arthritis. By combining data from >140,000 individuals of European ancestry within the Global Urate Genetics Consortium (GUGC), we identified and replicated 28 genome-wide significant loci in association with serum urate concentrations (18 new regions in or near TRIM46, INHBB, SFMBT1, TMEM171, VEGFA, BAZ1B, PRKAG2, STC1, HNF4G, A1CF, ATXN2, UBE2Q2, IGF1R, NFAT5, MAF, HLF, ACVR1B-ACVRL1 and B3GNT4). Associations for many of the loci were of similar magnitude in individuals of non-European ancestry. We further characterized these loci for associations with gout, transcript expression and the fractional excretion of urate. Network analyses implicate the inhibins-activins signaling pathways and glucose metabolism in systemic urate control. New candidate genes for serum urate concentration highlight the importance of metabolic control of urate production and excretion, which may have implications for the treatment and prevention of gout.

Motor Vehicle Crash Fatalities for Week Ending, April 18, 2008

Motor Vehicle Crash Fatalities

EPI Update, April 18, 2008

Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public Health.