COMPARAÇÃO DE MEDIDAS CEFALOMÉTRICAS DOS ESPAÇOS AÉREOS NASO E OROFARÍNGEO ENTRE RESPIRADORES NASAIS E ORAIS

A literatura tem evidenciado que o modo respiratório alterado influencia nos aspectos estruturais e funcionais do sistema estomatognático. Objetivo: Comparar as medidas cefalométricas dos espaços aéreos naso e orofaríngeo entre respiradores nasais e com modo respiratório alterado (orais ou oronasais). Método: Este estudo de caráter exploratório e retrospectivo utilizou os prontuários de pacientes atendidos na Clínica de Ortodontia, compreendendo o período de 2000 a 2009, sendo que dos 87 indivíduos (má oclusão Classe I de Angle) que compuseram a amostra, 55 eram respiradores nasais (RN) e 32 apresentavam modo respiratório alterado (RON - oronasal ou oral), 47 pertenciam ao sexo feminino e 40 ao masculino, com idades entre 8,75 e 22 anos (média de 14,78 anos). Foram analisadas as telerradiografias em norma lateral, não submetidos a tratamento ortodôntico ou fonoaudiológica prévios. As variáveis de análise foram: idade, sexo, raça, modo respiratório e análise dos espaços naso e orofaringeano pelo método adotado por Zanelato. Por meio de análise estatística (teste t de Student e quiquadrado), os resultados foram interpretados quanto à sua significância. Resultados: Houve diferença estatisticamente significante quanto à idade dos grupos (RN>RON); de prevalência de homens (maior no grupo RON), de leucodermas em ambos os grupos, de via aérea súpero-anterior (menor no grupo RON) e tonsila faríngea (maior no grupo RON); e de tamanho de tonsila faríngea em melanodermas. As demais variáveis de análise não evidenciaram diferenças estatisticamente significantes. Conclusão: As medidas cefalométricas do espaço nasofaringeano (menor no grupo RON) e da tonsila faríngea (maior no grupo RON) diferiram entre os grupos e o espaço orofaringeano não se mostrou diferente entre os grupos. Demais fatores, que não exclusivamente o espaço nasofaríngeo e a tonsila faríngea, podem predispor o indivíduo à respiração oronasal ou predominantemente oral e o ortodontista, em sua rotina clínica, pode avaliar objetivamente as particularidades de cada caso e, desta forma, proceder com condutas adequadas o mais precocemente possível.

A interseccionalidade de gênero, raça e classe no Programa Ciência sem Fronteiras : um estudo sobre estudantes brasileiros com destino aos EUA

Dissertação (mestrado)—Universidade de Brasília, Faculdade de Educação, Departamento de Pós-Graduação, Mestrado Profissional em Educação, 2015.

Evaluación de la posición hioidea en radiografías de pacientes clase I, II y III esqueletales entre 9 y 18 años de edad registrados en el período 2012 y 2015, de un Centro Radiológico de la Ciudad de Cuenca

Objetivo: El objetivo del presente estudio descriptivo, fue evaluar la posición del hueso hioides en los diferentes patrones esqueletales de Clase I, II y III mediante el trazado cefalométrico del triángulo hioideo propuesto por Bibby y Preston, estableciendo diferencias entre cada clase esqueletal. Materiales y métodos: La muestra consistió en 161 radiografías cefálicas laterales digitales, correspondientes a individuos de ambos sexos (75 hombres y 86 mujeres), entre edades de 9 y 18 años, las mismas que fueron divididas en tres subgrupos (Clase I, clase II y clase III) de acuerdo a los ángulos ANB y APDI. Se determinó la posición anteroposterior, vertical y angular del hueso hioides mediante el trazado cefalométrico del triángulo hioideo siendo el mentón, la tercera vértebra cervical y el hueso hioides las estructuras anatómicas utilizadas para el trazado del mismo. Se obtuvieron medidas estándar para cada clase esqueletal. Resultados: Se observaron diferencias estadísticamente significativas en la medida de H-Rgn entre clase I y II y entre clase II y III (p<0,005). El valor del ángulo del plano hioidal presentó diferencias estadísticamente significativas entre clase I y III y entre clase II y III (p<0,005). Se evidenciaron diferencias estadísticamente significativas entre hombres y mujeres con clase I esqueletal en la medida H-Rgn (p<0,005). Conclusiones: La posición del hueso hioides varía en los diferentes patrones esqueletales. Sin embargo, su posición en relación a la columna cervical presenta menos variabilidad que su relación con la mandíbula

Necessidade e procura do tratamento ortodôntico na consulta da clínica universitária do ISCSEM

Dissertação para obtenção do grau de Mestre no Instituto Superior de Ciências da Saúde Egas Moniz

Potencialidade do sensor Worldview II na detecção de hematita e goethita em solos tropicais

Dissertação (mestrado)—Universidade de Brasília, Instituto de Geociências, Programa de Pós-Graduação Stricto Sensu em Geociências Aplicadas, 2016.

Classe de Mathématiques réalité et communication

Cette étude se concentre sur une expérience d'enseignement exploratoire des mathématiques (EEM), réalisée avec des élèves de 5ème année, dans laquelle on établit une forte connexion avec la réalité et on intensifie la capacité de communication des élèves, tout en promouvant la résolution de problèmes et le raisonnement mathématique. Les leçons de mathématiques sont organisées en quatre phases: (i) Lancement de la tâche aux élèves; (ii) Développement de la tâche; (iii) Discussion de la tâche; et (iv) Systématisation de l’apprentissage mathématique. Afin de préparer la discussion de la tâche, l'enseignante a mis en œuvre la galerie des tâches, grâce à laquelle les élèves ont leur premier contact avec les résolutions de leurs collègues: ils peuvent poser des questions et enregistrer des commentaires dans les feuilles exposées. Cet article présente les résultats d'une leçon sur les pourcentages, dans laquelle les élèves ont travaillé la tâche intitulée « Rabais au Bit-@-Byte ». L'analyse de cette tâche ainsi que les résultats des tâches similaires de la réalité effectuées tout au long de l'année scolaire montrent que le modèle d'enseignement exploratoire des mathématiques (EEM) permet des améliorations dans l'apprentissage des mathématiques au niveau des concepts et aussi des capacités transversales comme le raisonnement, la communication et la résolution de problèmes mathématiques.

L'Intégration d'un Module d'Étude Internet Dans la Classe de Comptabilité: Perceptions des Élèves et les Résultats Académiques

Implemented in the context of Business Administration students enrolled in a college level three year technology program, this research investigated students’ perceptions and academic results concurrent with the implementation of an online web module designed to facilitate student self-study. The students involved in this research were enrolled in a program that, while offering a broad education in business disciplines, specialized in the field of accounting. As a result, students were enrolled in academically rigorous accounting courses in each of the six semesters of the program. The weighting of these accounting courses imposes a significant self-study component – typically matching or exceeding the time spent in class. In this context many of the students enrolled in the Business Administration Program have faced difficulties completing the self-study component of the course effectively as demonstrated in low homework completion rates, low homework grade averages and ultimately low success rates in the courses. In an attempt to address this situation this research studied the implementation of a web-based self-study module. Through this module students could access a number of learning tools that were designed to facilitate the self-study process under the premise that more effective self-study learning tools will help remove obstacles and provide more timely confirmation of learning during student self-study efforts. This research collected data from a single cohort of students drawn from the first three sequential accounting courses of the Business Administration Program. The web-based self-study module was implemented in the third of the three sequential accounting courses. The first two of these courses implemented a traditional manual self-study environment. Data collected from the three accounting courses included homework completion rates, homework, exam and final grades for the respective courses. In addition the web-study module allowed the automatic reporting of student usage of a number of specific online learning tools. To complement the academic data, students were surveyed to gain insight into their perceptions of the effectiveness of the web-based system. The research provided a number of interesting insights. First among these was a confirmation of the importance of the self-study process in the academic achievement of the learners. Regardless of the self-study environment, manual or web-enhanced, a significant positive correlation existed between the students’ self-study results, demonstrated in both homework completion rates and homework averages and the corresponding final grades. These results confirm the importance of self-study found generally in the prevailing academic literature regarding students enrolled in higher education. In addition, the web-enhanced learning environment implemented during the third accounting course coincided with significantly higher homework completion rates and corresponding homework averages: homework completion rates in particular increased from a combined average of 63% in the first two accounting courses to 93% in the web-enhanced context of the third accounting course. Moreover, the homework completion rates of the web-enhanced course were evenly distributed across the cohort of students. A quartile-based analysis was subsequently completed. Quartiles were constructed by ranking the students according to their combined average homework completion rates from the first two manual self-study courses, Accounting I and II. The quartile-based homework completion rates for the manual self-study courses Accounting I and II were subsequently compared to the results these same quartiles of students achieved in the web-based self-study within Accounting III. While the first two courses demonstrated significantly uneven homework completion rates across the quartiles ranging from 31% to 91% homework completion rates, the differences among the four quartiles within the web-enhanced module, with an average homework completion rate of 93%, were statistically insignificant. Congruent with the positive academic results observed in the third, web-enhanced course, through the corresponding survey, students expressed a strong attitude in favor of the online self-study environment. This research was designed to add to the existing research that studies the implementation of learning in an online setting. Specifically, the research was designed to explore a middle ground of online learning – a web-enhanced course – a context that supplements the classroom experience rather than replacing it. The web-enhanced accounting course demonstrated impressive favorable results, both academically and in terms of students' perception of the system; these results suggest that a web-enhanced environment can provide learning tools that facilitate the self-study process while providing a structured learning environment that can help developing learners reach their potential.

Melhoria da qualidade da atenção à saúde da pessoa idosa na Unidade Básica de Saúde Piquiri II, Canguaretama/RN

O aumento recente na expectativa de vida no Brasil resultante da mudança demográfica vem despertando a atenção dos gestores e dos servidores em saúde pública. O número de idosos em acompanhamento no SUS está crescendo em uma proporção maior do que o número de profissionais de saúde adequadamente habilitados para lidar com essa classe de usuário. Este projeto tem como objetivo geral melhorar a atenção à saúde da pessoa idosa no âmbito da atenção básica da seguinte maneira: ampliar a cobertura de acompanhamento, melhorar a adesão e a qualidade da atenção desses usuários, melhorar o registro das informações, mapear os idosos de risco na área de abrangência e promover a saúde. Essa sistematização foi amparada pelo uso da planilha de Objetivos, Metas, Indicadores e Ações (OMIA) e posta em prática com o preenchimento da ficha espelho e da planilha de coleta de dados durantes as atividades cotidianas. Foram cadastrados no programa apenas os usuários que foram atendidos durante as 12 semanas de intervenção. Após três meses de intervenção, foi observado um crescimento da proporção de atendimentos para idosos (de 13,2% para 20,2%), mesmo sem o cumprimento da meta inicial de cadastrar 80% dos idosos – 21,9% foram cadastrados no programa. As visitas domiciliares também aumentaram a frequência, sendo feito o cadastro de 81,2% dos idosos acamados e/ou com dificuldade de deambulação. Foi feito o rastreio para Hipertensão Arterial Sistêmica (HAS) e Diabetes Mellitus (DM) em 100% dos idosos acompanhados. Observou-se que 83,5% dos usuários tiveram acesso aos medicamentos prescritos. 100% deles receberam orientação para a adoção de hábitos alimentares saudáveis, e 68,2% foram orientados quanto a prática regular de atividade física. No entanto, as metas para o acompanhamento odontológico não foram atingidas. Ao final do período de observação, pudemos concluir que ocorreu crescimento tanto na quantidade como na qualidade da atenção direcionada aos idosos na UBS Piquiri II, mas os esforços devem ser continuados para que os resultados permaneçam em crescimento.

Mucopolysaccharidosis Type Ii: Identification Of 30 Novel Mutations Among Latin American Patients.

In this study, 103 unrelated South-American patients with mucopolysaccharidosis type II (MPS II) were investigated aiming at the identification of iduronate-2-sulfatase (IDS) disease causing mutations and the possibility of some insights on the genotype-phenotype correlation The strategy used for genotyping involved the identification of the previously reported inversion/disruption of the IDS gene by PCR and screening for other mutations by PCR/SSCP. The exons with altered mobility on SSCP were sequenced, as well as all the exons of patients with no SSCP alteration. By using this strategy, we were able to find the pathogenic mutation in all patients. Alterations such as inversion/disruption and partial/total deletions of the IDS gene were found in 20/103 (19%) patients. Small insertions/deletions/indels (<22 bp) and point mutations were identified in 83/103 (88%) patients, including 30 novel mutations; except for a higher frequency of small duplications in relation to small deletions, the frequencies of major and minor alterations found in our sample are in accordance with those described in the literature.

Reduced Plasma Angiotensin Ii Levels Are Reversed By Hydroxyurea Treatment In Mice With Sickle Cell Disease.

Sickle cell disease (SCD) pathogenesis leads to recurrent vaso-occlusive and hemolytic processes, causing numerous clinical complications including renal damage. As vasoconstrictive mechanisms may be enhanced in SCD, due to endothelial dysfunction and vasoactive protein production, we aimed to determine whether the expression of proteins of the renin-angiotensin system (RAS) may be altered in an animal model of SCD. Plasma angiotensin II (Ang II) was measured in C57BL/6 (WT) mice and mice with SCD by ELISA, while quantitative PCR was used to compare the expressions of the genes encoding the angiotensin-II-receptors 1 and 2 (AT1R and AT2R) and the angiotensin-converting enzymes (ACE1 and ACE2) in the kidneys, hearts, livers and brains of mice. The effects of hydroxyurea (HU; 50-75mg/kg/day, 4weeks) treatment on these parameters were also determined. Plasma Ang II was significantly diminished in SCD mice, compared with WT mice, in association with decreased AT1R and ACE1 expressions in SCD mice kidneys. Treatment of SCD mice with HU reduced leukocyte and platelet counts and increased plasma Ang II to levels similar to those of WT mice. HU also increased AT1R and ACE2 gene expression in the kidney and heart. Results indicate an imbalanced RAS in an SCD mouse model; HU therapy may be able to restore some RAS parameters in these mice. Further investigations regarding Ang II production and the RAS in human SCD may be warranted, as such changes may reflect or contribute to renal damage and alterations in blood pressure.

Phtx-ii A Basic Myotoxic Phospholipase A2 From Porthidium Hyoprora Snake Venom, Pharmacological Characterization And Amino Acid Sequence By Mass Spectrometry.

A monomeric basic PLA2 (PhTX-II) of 14149.08 Da molecular weight was purified to homogeneity from Porthidium hyoprora venom. Amino acid sequence by in tandem mass spectrometry revealed that PhTX-II belongs to Asp49 PLA2 enzyme class and displays conserved domains as the catalytic network, Ca2+-binding loop and the hydrophobic channel of access to the catalytic site, reflected in the high catalytic activity displayed by the enzyme. Moreover, PhTX-II PLA2 showed an allosteric behavior and its enzymatic activity was dependent on Ca2+. Examination of PhTX-II PLA2 by CD spectroscopy indicated a high content of alpha-helical structures, similar to the known structure of secreted phospholipase IIA group suggesting a similar folding. PhTX-II PLA2 causes neuromuscular blockade in avian neuromuscular preparations with a significant direct action on skeletal muscle function, as well as, induced local edema and myotoxicity, in mice. The treatment of PhTX-II by BPB resulted in complete loss of their catalytic activity that was accompanied by loss of their edematogenic effect. On the other hand, enzymatic activity of PhTX-II contributes to this neuromuscular blockade and local myotoxicity is dependent not only on enzymatic activity. These results show that PhTX-II is a myotoxic Asp49 PLA2 that contributes with toxic actions caused by P. hyoprora venom.

[impact Of The Activation Of Intention To Perform Physical Activity In Type Ii Diabetics: A Randomized Clinical Trial].

Type II diabetes mellitus is a highly prevalent disease among the adult Brazilian population, and one that can be controlled by interventions such as physical activity, among others. The aim of this randomized controlled study was to evaluate the impact of a traditional motivational strategy, associated with the activation of intention theory, on adherence to physical activity in patients with type II, diabetes mellitus who are part of the Unified Health System (SUS). Participants were divided into a control group (CG) and an intervention group (IG). In both groups, the traditional motivational strategy was applied, but the activation of intention strategy was only applied to the IG Group. After a two-month follow-up, statistically significant differences were verified between the groups, related to the practice of walking (p = 0.0050), number of days per week (p = 0.0076), minutes per day (p = 0.0050) and minutes walking per week (p = 0.0015). At the end of the intervention, statistically significant differences in abdominal circumference (p = 0.0048) between the groups were observed. The conclusion drawn is that the activation of intention strategy had greater impact on adherence to physical activity and reduction in abdominal circumference in type II diabetics, than traditional motivational strategy.

Comparação da eficiência do processo de ozonização e ozonização catalítica (Mn II e Cu II) na degradação de fenol

This paper discusses the results obtained with homogeneous catalytic ozonation [Mn (II) and Cu (II)] in phenol degradation. The reduction of total phenols and total organic carbon (TOC) and the ozone consumption were evaluated. The efficiency in phenol degradation (total phenol removal) at pH 3, with the catalytic process (Mn (II)), increased from 37% to 55% while the TOC removal increased from 4 to 63% in a seven-minute treatment. The ozonation process efficiency at pH 10 was 43% and 39% for phenol and TOC removal, respectively. The presence of both metallic ions (Mn2+ and Cu+2) in the ozonation process resulted in a positive effect.

Experimentação em química de compostos organometálicos: preparação do cloreto de dicarbonilciclopentadienilferro(II)

In this work, we describe a new method for obtaining [Fe(CO)2[(eta5-C5H5)Cl] employing simple techniques and low-cost reagents. It is worth mentioning that this method is faster than others reported in the literature. It was applied in laboratory classes for undergraduate students, exploring different concepts in organometallic chemistry and discussing the steps involved in the synthetic route.