Nutrition Society Silver Medal Lecture Nutrigenetics and personalised nutrition: how far have we progressed and are we likely to get there?

Nutrigenetics and personalised nutrition are components of the concept that in the future genotyping will be used as a means of defining dietary recommendations to suit the individual. Over the last two decades there has been an explosion of research in this area, with often conflicting findings reported in the literature. Reviews of the literature in the area of apoE genotype and cardiovascular health, apoA5 genotype and postprandial lipaemia and perilipin and adiposity are used to demonstrate the complexities of genotype-phenotype associations and the aetiology of apparent between-study inconsistencies in the significance and size of effects. Furthermore, genetic research currently often takes a very reductionist approach, examining the interactions between individual genotypes and individual disease biomarkers and how they are modified by isolated dietary components or foods. Each individual possesses potentially hundreds of 'at-risk' gene variants and consumes a highly-complex diet. In order for nutrigenetics to become a useful public health tool, there is a great need to use mathematical and bioinformatic tools to develop strategies to examine the combined impact of multiple gene variants on a range of health outcomes and establish how these associations can be modified using combined dietary strategies.

'Outside Architecture': lecture at The British School at Rome

Renshaw and Donszelmann lecture on their projects for the collaborative group 'Outside Architecture' this was part of a series of papers on the subject of architecture and art curated by The British School at Rome

Plenary Lecture 2: Milk and dairy produce and CVD: new perspectives on dairy and cardiovascular health

Cardiovascular diseases (CVD) are the leading cause of mortality and morbidity worldwide. One of the key dietary recommendations for CVD prevention is reduction of saturated fat intake. Yet despite milk and dairy foods contributing on average 27 % of saturated fat intake in the UK diet, evidence from prospective cohort studies does not support a detrimental effect of milk and dairy foods on risk of CVD. This paper provides a brief overview of the role of milk and dairy products in the diets of UK adults, and will summarise the evidence in relation to the effects of milk and dairy consumption on CVD risk factors and mortality. The majority of prospective studies and meta-analyses examining the relationship between milk and dairy product consumption and risk of CVD show that milk and dairy products, excluding butter, are not associated with detrimental effects on CVD mortality or risk biomarkers, that include serum LDL cholesterol. In addition, there is increasing evidence that milk and dairy products are associated with lower blood pressure and arterial stiffness. These apparent benefits of milk and dairy foods have been attributed to their unique nutritional composition, and suggest that the elimination of milk and dairy may not be the optimum strategy for CVD risk reduction.

A typical lecture room

This illustrates a typical lecture room at the New York Trade School taken during a class. Black and white photograph.

Electrical Lecture

Students fill a lecture room at the New York Trade School. The illustration on the board indicates that this is probably a lecture in the Electrical Department. Black and white photograph.

Le poète errant à Port-au-Prince : Une lecture de _Parias_ de Magloire Saint-Aude

Cet article offre une analyse de la figure du flâneur dans Parias: documentaire de l’écrivain haïtien Magloire-Saint-Aude (1912-1971). Étudiant la façon dont il se réapproprie de ce trope surréaliste dans un cadre port-au-princien, le but est de montrer que l’auteur essaie de repenser le sujet haïtien. L’article démontre que Magloire-Saint-Aude se sert d’un chronotope urbain double, d’abord les rues pauvres où les personnages déambulent sans but fixe et ensuite les salons bourgeois où naît le désir. Son flâneur haïtien subit un processus complexe de subjectivation qui s’articule dans la tension de ces deux chronotopes urbains. Même si le héros saint-audien essaye de se libérer par le biais de l’amour pour une Française il est à jamais attaché à l’espace exigu de Port-au-Prince. Cela vient rompre avec une tradition d’affirmation héroïque du sujet (masculin) haïtien. ”Exilé de l’intérieur,” Malgoire-Saint-Aude explore un sujet insaisissable qui garde ouverte sa part à l’altérité.

De "l'ermite" Ã "zone" : une lecture d'alcools de Guillaume Apollinaire

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La nation et ses mutations : une lecture d'une paix royale, roman belge francophone contemporain de Pierre Mertens

O presente estudo tem como objeto final a análise do romance belga francófono contemporâneo Une paix royale, publicado em 1995 por Pierre Mertens. No que diz respeito a um espaço nacional sem conformidade com o modelo canônico do Estadonação, quer-se evidenciar o estatuto de uma poética romanesca no seu processo de invenção do mito da nação e as peculiaridades da representação nacional que essa poética contribui a gerar. Tal abordagem do texto literário tem como pressuposto um estudo teórico sobre o conceito de nação, do qual são apresentadas uma história e uma definição. Também é levada em consideração a natureza das relações que a ficção romanesca estabelece com o mito da nação: a invenção do mesmo – que pode incluir sua desconstrução - utiliza uma linguagem específica da qual o romance e o campo literário em geral são enunciadores privilegiados. Essas considerações teóricas abrem caminho para um método interpretativo de textos francófonos que são os portadores contemporâneos do mito da nação belga, ou seja, manifestos publicados por intelectuais e por escritores entre 1976 e 2003, e o romance Une paix royale. A tese manifesta o papel criativo das Letras belgas francófonas na renovação da nação, que conserva uma atualidade