Gene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8.

The DNA-activated serine/threonine protein kinase (DNA-PK) is composed of a large (approximately 460 kDa) catalytic polypeptide (DNA-PKcs) and Ku, a heterodimeric DNA-binding component (p70/p80) that targets DNA-PKcs to DNA. A 41-kbp segment of the DNA-PKcs gene was isolated, and a 7902-bp segment was sequenced. The sequence contains a polymorphic Pvu II restriction enzyme site, and comparing the sequence with that of the cDNA revealed the positions of nine exons. The DNA-PKcs gene was mapped to band q11 of chromosome 8 by in situ hybridization. This location is coincident with that of XRCC7, the gene that complements the DNA double-strand break repair and V(D)J recombination defects (where V is variable, D is diversity, and J is joining) of hamster V3 and murine severe combined immunodeficient (scid) cells.

A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3.

Deletion of the short arm of human chromosome 1 is the most common cytogenetic abnormality observed in neuroblastoma. To characterize the region of consistent deletion, we performed loss of heterozygosity (LOH) studies on 122 neuroblastoma tumor samples with 30 distal chromosome 1p polymorphisms. LOH was detected in 32 of the 122 tumors (26%). A single region of LOH, marked distally by D1Z2 and proximally by D1S228, was detected in all tumors demonstrating loss. Also, cells from a patient with a constitutional deletion of 1p36, and from a neuroblastoma cell line with a small 1p36 deletion, were analyzed by fluorescence in situ hybridization. Cells from both sources had interstitial deletions of 1p36.2-36.3 which overlapped the consensus region of LOH defined by the tumors. Interstitial deletion in the constitutional case was confirmed by allelic loss studies using the panel of polymorphic markers. Four proposed candidate genes--DAN, ID3 (heir-1), CDC2L1 (p58), and TNFR2--were shown to lie outside of the consensus region of allelic loss, as defined by the above deletions. These results more precisely define the location of a neuroblastoma suppressor gene within 1p36.2-36.3, eliminating 33 centimorgans of proximal 1p36 from consideration. Furthermore, a consensus region of loss, which excludes the four leading candidate genes, was found in all tumors with 1p36 LOH.

Ordered restriction endonuclease maps of yeast artificial chromosomes created by optical mapping on surfaces.

We have developed a surface mounting technology for the rapid construction of ordered restriction maps from individual DNA molecules. Optical restriction maps constructed from yeast artificial chromosome DNA molecules mounted on specially derivatized glass surfaces are accurate and reproducible, and the technology is amenable to automation. The mounting procedures described here should also be useful for fluorescence in situ hybridization studies. We believe these improvements to optical mapping will further stimulate the development of nonelectrophoretic approaches to genome analysis.

Black maps/vivid waters : beauty and horror in David Maisel's The Lake Project and Terminal Mirage

"This paper examines The Lake Project and Terminal Mirage, the two components of David Maisel’s Black Maps series that concern water. Like the section of the Salt Lake chosen by Robert Smithson for his seminal Spiral Jetty, the alkaline waters Maisel photographs are subject to infestations of bacteria that that give them a visceral hue. Smithson provides a reference for this work; the artists are notable for their shared site, disorienting scale, and attraction to entropy"

Genera et species Curculionidum, cum synonymia hujus familae species novæ / a C.J. Schoenherr ; species novae aut hactenus minus cognitae, descriptionibus a L. Gyllenhal, C. H. Boheman entomologis aliis illustratæ.

1

Genera et species Curculionidum, cum synonymia hujus familae species novæ / a C.J. Schoenherr ; species novae aut hactenus minus cognitae, descriptionibus a L. Gyllenhal, C. H. Boheman entomologis aliis illustratæ.

3

Genera et species Curculionidum, cum synonymia hujus familae species novæ / a C.J. Schoenherr ; species novae aut hactenus minus cognitae, descriptionibus a L. Gyllenhal, C. H. Boheman entomologis aliis illustratæ.

5

Genera et species Curculionidum, cum synonymia hujus familae species novæ / a C.J. Schoenherr ; species novae aut hactenus minus cognitae, descriptionibus a L. Gyllenhal, C. H. Boheman entomologis aliis illustratæ.

4

Genera et species Curculionidum, cum synonymia hujus familae species novæ / a C.J. Schoenherr ; species novae aut hactenus minus cognitae, descriptionibus a L. Gyllenhal, C. H. Boheman entomologis aliis illustratæ.

2

Genera et species Curculionidum, cum synonymia hujus familae species novæ / a C.J. Schoenherr ; species novae aut hactenus minus cognitae, descriptionibus a L. Gyllenhal, C. H. Boheman entomologis aliis illustratæ.

7

Genera et species Curculionidum, cum synonymia hujus familae species novæ / a C.J. Schoenherr ; species novae aut hactenus minus cognitae, descriptionibus a L. Gyllenhal, C. H. Boheman entomologis aliis illustratæ.

8

Genera et species Curculionidum, cum synonymia hujus familae species novæ / a C.J. Schoenherr ; species novae aut hactenus minus cognitae, descriptionibus a L. Gyllenhal, C. H. Boheman entomologis aliis illustratæ.

6

The brown-tail moth, Euproctis chrysorrhcea (L.). A report on the life history and habits of the imported brown-tail moth, together with a description of the remedies best suited for destroying it. By Charles H. Fernald ... and Archie H. Kirkland ... Pub. under the direction of the State board of agriculture by authority of the legislature.

1903

New birds from Chile, by C. E. Hellmayr. Reports on results of the Captain Marshall Field expeditions.

v.12:no.5(1924)