933 resultados para Gerlach, Joe


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Lucas (2000) estimates that the US welfare costs of inflation are around 1% of GDP. This measurement is consistent with a speci…c distorting channel in terms of the Bailey triangle under the demand for monetary base schedule (outside money): the displacement of resources from the production of consumption goods to the household transaction time à la Baumol. Here, we consider also several new types of distortions in the manufacturing and banking industries. Our new evidences show that both banks and firms demand special occupational employments to avoid the inflation tax. We de…ne the concept of ”the foat labor”: The occupational employments that are aflected by the in‡ation rates. More administrative workers are hired relatively to the bluecollar workers for producing consumption goods. This new phenomenon makes the manufacturing industry more roundabout. To take into account this new stylized fact and others, we redo at same time both ”The model 5: A Banking Sector -2” formulated by Lucas (1993) and ”The Competitive Banking System” proposed by Yoshino (1993). This modelling allows us to characterize better the new types of misallocations. We …nd that the maximum value of the resources wasted by the US economy happened in the years 1980-81, after the 2nd oil shock. In these years, we estimate the excess resources that are allocated for every speci…c distorting channel: i) The US commercial banks spent additional resources of around 2% of GDP; ii) For the purpose of the firm foating time were used between 2.4% and 4.1% of GDP); and iii) For the household transaction time were allocated between 3.1% and 4.5 % of GDP. The Bailey triangle under the demand for the monetary base schedule represented around 1% of GDP, which is consistent with Lucas (2000). We estimate that the US total welfare costs of in‡ation were around 10% of GDP in terms of the consumption goods foregone. The big di¤erence between our results and Lucas (2000) are mainly due to the Harberger triangle in the market for loans (inside money) which makes part of the household transaction time, of the …rm ‡oat labor and of the distortion in the banking industry. This triangle arises due to the widening interest rates spread in the presence of a distorting inflation tax and under a fractionally reserve system. The Harberger triangle can represent 80% of the total welfare costs of inflation while the remaining percentage is split almost equally between the Bailey triangle and the resources used for the bank services. Finally, we formulate several theorems in terms of the optimal nonneutral monetary policy so as to compare with the classical monetary theory.

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In her victory speech, President Dilma Rousseff said she did not believe the nation’s closest election in a generation had divided Brazil. But she only needed to go online to see the civil war raging on social media to see how much the campaign had split Brazil, pitting rich against poor, friend against friend.

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The ways in which Internet traffic is managed have direct consequences on Internet users’ rights as well as on their capability to compete on a level playing field. Network neutrality mandates to treat Internet traffic in a non-discriminatory fashion in order to maximise end users’ freedom and safeguard an open Internet. This book is the result of a collective work aimed at providing deeper insight into what is network neutrality, how does it relates to human rights and free competition and how to properly frame this key issue through sustainable policies and regulations. The Net Neutrality Compendium stems from three years of discussions nurtured by the members of the Dynamic Coalition on Network Neutrality (DCNN), an open and multistakeholder group, established under the aegis of the United Nations Internet Governance Forum (IGF).

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O sistema plantio direto preconiza o uso de culturas de cobertura para produção de massa seca sobre o solo. O presente trabalho teve por objetivo estudar a produção e a taxa de decomposição de duas coberturas vegetais - crotalária juncea (Crotalária juncea L.) e mucuna-cinza (Stilozobium niveum L) - em três sistemas de manejo (rolo-faca, triturador de palhas e herbicida), e a capacidade de campo efetiva dos manejos. O experimento foi realizado na área do Laboratório de Máquinas e Mecanização Agrícola (LAMMA), do Departamento de Engenharia Rural, UNESP, Jaboticabal - SP, com delineamento em blocos ao acaso, em esquema fatorial 3x2, originando seis tratamentos, com quatro repetições. Foram analisadas as produções de massa seca das culturas de cobertura antes e após o manejo, a velocidade de deslocamento e a capacidade de campo efetiva para cada conjunto (trator-equipamento). As análises dos valores obtidos permitiram verificar que o fator manejo não interfere na decomposição da massa seca das coberturas vegetais e que as duas culturas de cobertura apresentaram massas semelhantes aos 30; 70 e 125 dias após a semeadura, diferindo aos 97 dias, época na qual a crotalária apresentou maior quantidade de massa seca. Aos 30; 51 e 71 dias após o manejo, as massas secas das culturas foram semelhantes. O manejo com herbicida apresentou maior capacidade de campo efetiva.

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To understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a core set of 14,345 orthologs shared among seven mammalian species of which 1217 are absent or undetected in noneutherian (marsupial or monotreme) genomes. Cattle-specific evolutionary breakpoint regions in chromosomes have a higher density of segmental duplications, enrichment of repetitive elements, and species-specific variations in genes associated with lactation and immune responsiveness. Genes involved in metabolism are generally highly conserved, although five metabolic genes are deleted or extensively diverged from their human orthologs. The cattle genome sequence thus provides a resource for understanding mammalian evolution and accelerating livestock genetic improvement for milk and meat production.

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During pregnancy, the maternal endocrine pancreas undergoes, as a consequence of placental lactogens and prolactin (PR,L) action, functional changes that are characterized by increased glucose-induced insulin secretion. After delivery, the maternal endocrine pancreas rapidly returns to nonpregnant state, which is mainly attributed to the increased serum levels of glucocorticoids (GCs). Although GCs are known to decrease insulin secretion and counteract PRL action, the mechanisms for these effects are poorly understood. We have previously demonstrated that signal transducer and activator of transcription 3 (STAT3) is increased in islets treated with PRL. In the present study, we show that STAT3 expression and serine phosphorylation are increased in pancreatic islets at the end of pregnancy (P19). STAT3 serine phosphorylation rapidly returned to basal levels 3 days after delivery (U). The expression of the sarcoendoplasmic reticulum Ca2+-ATPase 2 (SERCA2), a crucial protein involved in the regulation of calcium handling in P-cells, was also increased in P19, returning to basal levels at L3. PRL increased SERCA2 and STAT3 expressions and STAT3 serine phosphorylation in RINm5F cells. The upregulation of SERCA2 by PRL was abolished after STAT3 knockdown. Moreover, PRL-induced STAT3 serine phosphorylation and SERCA2 expression were inhibited by dexamethasone (DEX). Insulin secretion from islets of PI 9 rats pre-incubated with thapsigargin and L3 rats showed a dramatic suppression of first phase of insulin release. The present results indicate that PRL regulates SERCA2 expression by a STAT3-dependent mechanism. PRL effect is counteracted by DEX and might contribute to the adaptation of maternal endocrine pancreas during the peripartum period.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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O nitrogênio é o nutriente aplicado em maior quantidade à cultura do feijão, o mais limitante ao crescimento e desenvolvimento das plantas e o que mais onera o custo de produção. Uma boa opção para o produtor diminuir custos, com a utilização de fertilizantes nitrogenados, é a utilização de plantas de cobertura do solo, também conhecidas como adubos verdes. Assim, este trabalho objetivou avaliar os custos de produção e índices de lucratividade de diferentes tratamentos envolvendo coberturas vegetais e doses de nitrogênio em cobertura, na cultura do feijoeiro irrigado, em sistema plantio direto, nas safras de inverno de 2010 e 2011. O trabalho foi realizado em área experimental localizada no município de Selvíria (MS), em Latossolo Vermelho distrófico típico. Os tratamentos constituíram-se de seis coberturas vegetais (Crotalaria juncea, milheto, guandú, Crotalaria juncea + milheto, guandú + milheto e pousio) e quatro doses de N (0 kg ha-1, 30 kg ha-1, 60 kg ha-1 e 90 kg ha-1). Foram estimados o custo operacional total, receita bruta, lucro operacional, índice de lucratividade, produtividade de equilíbrio e o preço de equilíbrio. Concluiu-se que o uso da Crotalaria juncea, como cobertura vegetal do solo, proporcionou os maiores valores de custo operacional total e lucro operacional e os melhores índices de lucratividade, e que o incremento nas doses de nitrogênio aumentou o custo operacional total, com tendência de aumento na produtividade e, consequentemente, no preço de equilíbrio.

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Background: In human medicine, transfusion of ABO-mismatched platelets has been associated with shortened platelet survival and refractoriness to platelet transfusion because of expression of certain blood group antigens on platelets. It remains unknown if canine platelets express dog erythrocyte antigens (DEAs). Objective: The aim of this study was to develop a flow cytometric assay for DEA 1.1 and determine whether DEA 1.1 is present on canine platelets.Methods: Blood was collected from 172 clinically healthy dogs. Platelets and erythrocytes from each dog were tested for DEA 1.1 by flow cytometry using anti-DEA 1.1 blood-typing sera. Erythrocytes from each dog were also assessed for DEA 1.1 using a standard tube-typing test (T1) and using a second tube method (T2), if the flow cytometric and T1 results differed.Results: Using flow cytometry, DEA 1.1 was detected on erythrocytes of all 110 dogs shown by T1 or T2 testing to be DEA 1.1-positive. Initial results of the T1 test had a diagnostic accuracy of 93% (160 correct/ 172 tests). The frequency of erythrocyte DEA 1.1 positivity in previously untyped dogs (n = 118) was 56%. DEA 1.1 expression was not detected on platelets from DEA 1.1-positive dogs.Conclusions: Flow cytometry was a reliable method for detection of DEA 1.1 on canine erythrocytes. The absence of DEA 1.1 on platelets from DEA 1.1-positive dogs suggests that their platelets do not express DEA 1.1 and will not induce production of anti-DEA 1.1 antibodies that might lead to platelet refractoriness or reactions to a subsequent transfusion of DEA 1.1positive erythrocytes.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)