Finding best urban routes based on analyses of high level and IOPT Petri net models

This paper presents a tool that combines two kinds of Petri Net analyses to set the fastest routes to one vehicle in a bounded area of traffic urban. The first analysis consists of the discovery of possible routes in a state space generated from an IOPT Petri net model given the initial marking as the vehicle position. The second analysis receives the routes found in the first analysis and calculates the state equations at incidence matrix created from the High Level Petri net model to define the fastest route for each vehicle that arrive in the roads. It was considered the exchange of information between vehicle and infrastructure (V2I) to get the position and speed of all vehicles and support the analyses. With the results obtained we conclude that is possible optimizing the urban traffic flow if this tool is applied to all vehicles in a bounded urban traffic. © 2012 IEEE.

Interclonal Variations in the Molecular Karyotype of Trypanosoma cruzi: Chromosome Rearrangements in a Single Cell-Derived Clone of the G Strain

Trypanosoma cruzi comprises a pool of populations which are genetically diverse in terms of DNA content, growth and infectivity. Inter- and intra-strain karyotype heterogeneities have been reported, suggesting that chromosomal rearrangements occurred during the evolution of this parasite. Clone D11 is a single-cell-derived clone of the T. cruzi G strain selected by the minimal dilution method and by infecting Vero cells with metacyclic trypomastigotes. Here we report that the karyotype of clone D11 differs from that of the G strain in both number and size of chromosomal bands. Large chromosomal rearrangement was observed in the chromosomes carrying the tubulin loci. However, most of the chromosome length polymorphisms were of small amplitude, and the absence of one band in clone D11 in relation to its reference position in the G strain could be correlated to the presence of a novel band migrating above or below this position. Despite the presence of chromosomal polymorphism, large syntenic groups were conserved between the isolates. The appearance of new chromosomal bands in clone D11 could be explained by chromosome fusion followed by a chromosome break or interchromosomal exchange of large DNA segments. Our results also suggest that telomeric regions are involved in this process. The variant represented by clone D11 could have been induced by the stress of the cloning procedure or could, as has been suggested for Leishmania infantum, have emerged from a multiclonal, mosaic parasite population submitted to frequent DNA amplification/deletion events, leading to a 'mosaic' structure with different individuals having differently sized versions of the same chromosomes. If this is the case, the variant represented by clone D11 would be better adapted to survive the stress induced by cloning, which includes intracellular development in the mammalian cell. Karyotype polymorphism could be part of the T. cruzi arsenal for responding to environmental pressure. © 2013 Lima et al.

Findings of the survey on international classifications in Latin America

Spanish document available at the Library

Mild cognitive impairment (part 2): Biological markers for diagnosis and prediction of dementia in Alzheimer's disease

To present a critical review of publications reporting on the rationale and clinical implications of the use of biomarkers for the early diagnosis of Alzheimer's disease (AD). Methods: We conducted a systematic search of the PubMed and Web of Science electronic databases, limited to articles published in English between 1999 and 2012, and based on the following terms: mild cognitive impairment, Alzheimer's disease OR dementia, biomarkers. We retrieved 1,130 articles, of which 175 were reviews. Overall, 955 original articles were eligible. Results: The following points were considered relevant for the present review: a) rationale for biomarkers research in AD and mild cognitive impairment (MCI); b) usefulness of distinct biomarkers for the diagnosis and prediction of AD; c) the role of multimodality biomarkers for the diagnosis and prediction of AD; d) the role of biomarkers in clinical trials of patients with AD and MCI; and e) current limitations to the widespread use of biomarkers in research and clinical settings. Conclusion: Different biomarkers are useful for the early diagnosis and prediction of AD in at-risk subjects. Nonetheless, important methodological limitations need to be overcome for widespread use of biomarkers in research and clinical settings. © 2013 Associação Brasileira de Psiquiatria.

Report of the Expert Group Meeting on the Caribbean Information Society

The meeting was convened as part of this office's strategy to continue to provide support to CDCC Member States in implementing the WSIS Plan of Action. The thirty two participants were in general knowledgeable about the Information Society activities of their respective governments and organisations. The objective of the meeting was to apprise CDCC Member Countries of the activities which the Secretariat had undertaken in the area of Information and Communications Technology for Development as a follow up to the Twentieth Session of the CDCC and in response to the resolution tabled at that session; to facilitate the exchange of information among countries and agencies in the region with respect to ICTs for development in general and the WSIS process in particular; hear reports on progress made at the national level, with special focus on the area of e-government and government policies in the area of ICTs; and to get a snapshot as to where the region is positioned vis a vis the WSIS agenda. A Caribbean ICT Stocktaking report was presented and there was an update on the e-LAC strategy. Several recommendations were made with respect to ECLAC's continuing involvement in this area - among them, that ECLAC should assist countries with preparing national e-strategies, develop strategic partnerships especially with the CARICOM Secretariat, develop databases and other information four use by the CDCC countries and continue its stocktaking work

Report on the production of trade statistics in the Caribbean region

Includes bibliography

Computerization of maritime ports, e-commerce platforms and logistics communities

In the past few years there has been a clear trend of attaching increasing importance to "inforstructures", or the capacity of ports to process the information that accompanies foreign trade flows, so that the processing becomes a facilitating factor for trade, rather than an obstacle.This led to development of the concept of a port community system, which is a computerized system that interconnects all the members of a logistics community, making the exchange of documentation as effective as possible, reducing the volume of data to be re-entered in different systems and ultimately improving the whole process of monitoring an operation until its completion. Computerization of communications between all the actors at the ports facilitates integration of the community, while it also assists interaction between ports, thus forming logistics corridors.

eHealth handbook for managers of healthcare services and systems

Prefacio de Alicia Bárcena y Luciano Sáez

A Semana: periódico literário

A vinda da família real para o Brasil, em 1808, trouxe grandes mudanças e entre elas a primeira manifestação periódica o Correio Brasiliense, editado em Londres. No início do século XX, sobretudo, com a Semana de Arte Moderna em 1922, surgem revistas como: Klaxon, Estética, Festa e outras. A partir delas editam-se outras que constituíram importantes documentos da sociedade brasileira e registram a nova tendência do público leitor. O Pará não ficou ausente desses acontecimentos e teve a Imprensa como seu principal veículo de divulgação. Algumas revistas e alguns jornais surgiram nessa época na capital do Estado, entre as quais se destacou a revista A Semana, que circulou por vinte e cinco anos. Esse semanário mantinha correspondência com outras regiões do Brasil: São Paulo, Rio de Janeiro, Recife, Maranhão. Nessas regiões havia colaboradores da revista, o que permitia a troca de informações do que acontecia no mundo literário e no mundo cultural. Dos periódicos compilados foram selecionados quatro exemplares do ano de 1939 para serem estudados, neste trabalho. Neles foram feitos levantamentos da capa, das publicações literárias, do gênero a que essas produções pertenciam e de seus respectivos autores. Pelo quadro-resumo feito dessas edições, percebeu-se que os editores procuravam seguir um padrão divulgando textos de cunho literário, como contos, poemas, trechos de romances, ensaios, entre outros. Em algumas dessas produções ficaram evidentes que nem todas absorveram a nova tendência estética que veio com A Semana de Arte Moderna, pois havia escritores que oscilavam entre as estéticas Romântica, Simbolista e Parnasiana. Por outro lado existiam aqueles que se destacavam, incorporando esse novo tempo literário. Em meio a essas produções despontava a figura feminina, num lugar de destaque, que além de ilustrarem a capa do periódico ainda apareciam nas páginas subseqüentes. Todas essas informações divulgadas no periódico deram mais credibilidade à Revista e permitiu que a Literatura Paraense fizesse parte desse novo momento da Literatura Brasileira.

Basic illocutions in the native languages of Brazil

This paper shows that the distribution of basic illocutions (defined as grammatical structures that can be related to a default communicative intentions) within and across the indigenous languages of Brazil can be described systematically in terms of a set of implicational hierarchies by means of which the existence of certain basic illocutions can be predicted from the existence of others. In doing so, a case is made for a major distinction between propositional and behavioural basic illocutions, the former having to do with the exchange of information, the latter with influencing behaviour.

Chiral transition of fundamental and adjoint quarks

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Interferences and interventions after acute myocardial infarction: an integrative review of the literature

Objective: to identify the interference of acute myocardial infarction (AMI) in the quality of life of affected, interventions and understanding by health professionals. Method: an integrative review, aiming to answer << What are the interference in the quality of life of post-AMI customers? >> and << What are the interventions proposed in order to minimize them? >>. We selected 12 articles available in the LILACS database, between 2000 and 2011, based on the criteria of inclusion and exclusion. Results: we have selected a total of 12 articles selected according to the inclusion and exclusion criteria pre-established. We obtained a classification into two themes (1) interference with quality of life and (2) proposals for interventions to minimize interference. Conclusions: highlights the importance of patient involvement in care plan well structured, multidisciplinary team integration and quantity of publications by heterogeneous country on the subject.

Optimized design of substrate-integrated hollow waveguides for mid-infrared gas analyzers

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Non-Markovianity through flow of information between a system and an environment

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Spectrophotometric evaluation of dental bleaching under orthodontic bracket in enamel and dentin

Aware of the diffusion capacity of bleaching in the dental tissues, many orthodontists are subjecting their patients to dental bleaching during orthodontic treatment for esthetic purposes or to anticipate the exchange of esthetic restorations after the orthodontic treatment. For this purpose specific products have been developed in pre-loaded whitening trays designed to fit over and around brackets and wires, with clinical efficacy proven. Objective: The objective of this study was to evaluate, through spectrophotometric reflectance, the effectiveness of dental bleaching under orthodontic bracket. Material and Methods: Thirty-two bovine incisors crown blocks of 8 mm x 8 mm height lengths were used. Staining of tooth blocks with black tea was performed for six days. They were distributed randomly into 4 groups (1-home bleaching with bracket, 2- home bleaching without bracket, 3- office bleaching with bracket, 4 office bleaching without bracket). The color evaluation was performed (CIE L * a * b *) using color reflectance spectrophotometer. Metal brackets were bonded in groups 1 and 3. The groups 1 and 2 samples were subjected to the carbamide peroxide at 15%, 4 hours daily for 21 days. Groups 3 and 4 were subjected to 3 in-office bleaching treatment sessions, hydrogen peroxide 38%. After removal of the brackets, the second color evaluation was performed in tooth block, difference between the area under the bracket and around it, and after 7 days to verified color stability. Data analysis was performed using the paired t-test and two-way variance analysis and Tukey’s. Results: The home bleaching technique proved to be more effective compared to the office bleaching. There was a significant difference between the margin and center color values of the specimens that were subjected to bracket bonding. Conclusions: The bracket bond presence affected the effectiveness of both the home and office bleaching treatments.