499 resultados para Aulo, Thea


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Mode of access: Internet.

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Vol. 2-3, Erfurt, C. Villaret.

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German translation, without original text.

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Includes bibliographical references.

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Top Row: Kristen Clark, Katherine Grinenko, Shinyi Tang, Troy Tann, Kelly Pasanen, Barbara Loson, Dennis Lake, Lisa Mancuso, Elizabeth Kim, Linda Dengate, Linda Morse, Stacey Horner, Juliet McKeone, Laura Schenk, Corrie Boguth

Row 2: Valerie Straka, Jamie T. Mose, Robert VanCamp, Cary Johnson, Laura Chamberlain, Kenyatta A. Paige, Kevin T. Sprecher, Jean L. Novak, Amanda Sue Niskar, Lisa Oliverio, Rosalyn Baumann, Elaine Schultz, Jennifer Lee Bastress, Kristen Hedge

Row 3: Jennifer Joh, Jennifer Monroe, Marion Tauriainen, Anne Chesky, Michael Fournier, Amy Sebright, Brian Simmons, Ann Luciano, Robin Van Eck, Beth Hart

Row 4: Jacqueline weibel, Dawn Garrett, Vicki McWalters, Malina Rocoff, Holly Medley, Ann Kosky, Tina L. Kessey, Caesanea A. Smith, Michelle Koch, Julie C. Wolf

Row 5: Robin Wygant, Cynthia Nichols, Susan Worek, Sandi Sassack, Timothy Wright, Bridgette Nichols, Kelly Sheridan, Kristin Sirosky, Kathy Kentala, Susan Oslund, Zaleha Williams, Heidi C. Goiz

Row 6: Kathryn Erdmann, Karen Crandall, Darryl Anderson, Karla Stoermer, Janice Lindberg, Beverly Jones, Rhetaugh G. Duman, Elisabeth Pennington, Violet Barkauskas, Laura Stock, Jacqueline Mickle, Catharine Quinn, Laura Nourse

Row 7: Christopher Kelly, Deborah Zolinski, Victoria Buckles, Pamela Brown, Stephanie Macey, Meredith Muncy, Susan, M. Smashey, Laura Welch, Rene Thompson, Sarah Scott, Juliette Lovell, Diane Ferguson, Deborah Ann Dolasinski, Cynthia Zammit, Lorie Malarney

Row 8: Janet Ingram, Rosemary Stafford, Diane Mayernik, Thea Picklesimer, Hannah Clark, JoyMarie Bruhowzki, Jennifer Beckert, Elizabeth Bryant, Jennifer Voeffray, Jane Perrin, Sophia Jan, Diana apostolou, Deborah Ruzicka, Liesel Culver

Row 9: Lori Wessman, Nicole Kerridge, Julia Oman, Melissa Naser, Jennifer Cole, Elizabeth Brickman, Detria Williams, Kris Haaksma, Alison Flaskamp, Nela L. Humm, Carol Taylor, Dena Mitchell, Karen L. Domke

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Growth hormone is believed to activate the growth hormone receptor (GHR) by dimerizing two identical receptor subunits, leading to activation of JAK2 kinase associated with the cytoplasmic domain. However, we have reported previously that dimerization alone is insufficient to activate full-length GHR. By comparing the crystal structure of the liganded and unliganded human GHR extracellular domain, we show here that there is no substantial change in its conformation on ligand binding. However, the receptor can be activated by rotation without ligand by inserting a defined number of alanine residues within the transmembrane domain. Fluorescence resonance energy transfer ( FRET), bioluminescence resonance energy transfer (BRET) and coimmunoprecipitation studies suggest that receptor subunits undergo specific transmembrane interactions independent of hormone binding. We propose an activation mechanism involving a relative rotation of subunits within a dimeric receptor as a result of asymmetric placement of the receptor-binding sites on the ligand.

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The nature of market orientation and its impact on business performance and other related outcomes have been extensively researched in a range of service contexts including tourism. In contrast, our understanding of the factors that influence market orientation is still limited. This paper reports on a study that contributes to our understanding of the determinants of market orientation within the tourism sector by focusing specifically on the role played by two strategically important variables, namely government regulation and ownership structure. The study analyses two national samples of hotels and travel services in the rapidly growing tourism industry in China. The hotel sector has been open to foreign investment for two decades and has a diversified ownership structure, whereas the travel services sector has been dominated by government owned firms and relatively closed to foreign investment. The results of the survey suggest that of the two new antecedents, only government regulation has a significant role to play in driving market orientation. Internally, access to appropriate managerial and marketing capabilities was identified as a significant predictor of the development of market orientation.