Anonymer arabischer Kommentar zu Maimonides' "Führer der Unschlüssigen" : 1. Teil, Kap- 41-61 ; nach Ms. Or. Oct. 258 (hebr.) zum erstenmal herausgegeben

Bern, Univ., Diss., 1906

Haematuria in two geldings caused by osteochondroma of the os pubis: Case reports and anatomic study of the os pubis in 41 cadaveric pelvises

Exostosis of the os pubis causing haematuria, and potentially cystorrhexis, in horses has not been described in the literature. In this study, 2 geldings that suffered from exercise-induced haematuria caused by an osteochondroma of the os pubis, and the assessment of 41 cadaveric pubic bones are reported on. The anatomy of the os pubis is highly variable. The prevalence of exostosis in the os pubis appears to be higher in male horses. Palpation and ultrasonography of the pelvis per rectum and cystoscopy are valuable diagnostic tools. Depending on the extent of changes in the bladder wall, surgical removal of the exostosis should be considered in order to prevent cystorrhexis. In horses that present with haematuria, closer assessment of the os pubis for the presence of an exostosis is warranted.

Psalm 41 : zur Feier der Einweihung des neu erbauten jüdischen Krankenhauses zu Berlin

von L. Lewandowski

Ms. hebr. oct. 41 - Derashot

Vorbesitzer: Aaron Ben-Moses Fuld

Bevacizumab continuation versus no continuation after first-line chemotherapy plus bevacizumab in patients with metastatic colorectal cancer: a randomized phase III non-inferiority trial (SAKK 41/06)

BACKGROUND Chemotherapy plus bevacizumab is a standard option for first-line treatment in metastatic colorectal cancer (mCRC) patients. We assessed whether no continuation is non-inferior to continuation of bevacizumab after completing first-line chemotherapy. PATIENTS AND METHODS In an open-label, phase III multicentre trial, patients with mCRC without disease progression after 4-6 months of standard first-line chemotherapy plus bevacizumab were randomly assigned to continuing bevacizumab at a standard dose or no treatment. CT scans were done every 6 weeks until disease progression. The primary end point was time to progression (TTP). A non-inferiority limit for hazard ratio (HR) of 0.727 was chosen to detect a difference in TTP of 6 weeks or less, with a one-sided significance level of 10% and a statistical power of 85%. RESULTS The intention-to-treat population comprised 262 patients: median follow-up was 36.7 months. The median TTP was 4.1 [95% confidence interval (CI) 3.1-5.4] months for bevacizumab continuation versus 2.9 (95% CI 2.8-3.8) months for no continuation; HR 0.74 (95% CI 0.58-0.96). Non-inferiority could not be demonstrated. The median overall survival was 25.4 months for bevacizumab continuation versus 23.8 months (HR 0.83; 95% CI 0.63-1.1; P = 0.2) for no continuation. Severe adverse events were uncommon in the bevacizumab continuation arm. Costs for bevacizumab continuation were estimated to be ∼30,000 USD per patient. CONCLUSIONS Non-inferiority could not be demonstrated for treatment holidays versus continuing bevacizumab monotheray, after 4-6 months of standard first-line chemotherapy plus bevacizumab. Based on no impact on overall survival and increased treatment costs, bevacizumab as a single agent is of no meaningful therapeutic value. More efficient treatment approaches are needed to maintain control of stabilized disease following induction therapy. CLINICAL TRIAL REGISTRATION ClinicalTrials.gov, number NCT00544700.

Tages-Ordnung für den 11ten Juli 1848: I. Vor dem Anfang der Berathung der Tages-Ordnung für den 4. Juli Nr. 41, 43. und 44.: Dr. Jacoby. Antrag: Die Preußische constituirende Versammlung kann den von der Deutschen National-Versammlung gefaßten Beschluß nicht billigen ...

Welsch (Projektbearbeiter): Zusammenstellung der am 11. Juli 1848 in der Preußischen Nationalversammlung gestellten Anträge und Interpellationen (von insgesamt 23 Abgeordneten)

Ms. germ. fol. 41 - Der Reichs-Stadt Regensburg Wachtgedings-Ordnung

Akzessionsnummer: 591/2054

Ms. Barth. 41 (Ausst. 18) - Collectio homiliarum de tempore. Pars aestivalis

Vorbesitzer: Bartholomaeusstift Frankfurt am Main;

Ms. germ. oct. 41 - Passionstraktat

Vorbesitzer: Hartwin von Ergerßheim

Ms. Praed. 41 - Libri aggregationum in medicinis simplicibus

Vorbesitzer: Georg von Breidenbach; Dominikanerkloster Frankfurt am Main

Ms. germ. oct. 28 (Ausst. 41) - Lateinisch-deutsches Gebetbuch für Dominikanerinnen

Vorbesitzer: Antonius Ediger; Elisabeth Ruprechtin; Anna Elisabetha Johannisin zu Leiselsheim; Johann Nicolaus Johannes

Ms.Ff.F.Stoltze 3. 41 - Brief von Albert Friedrich Benno Dulk an Friedrich Stoltze

Verlorener Brief an Stoltze, Der wahre Jakob, Bitte um Übertragung einiger Texte ins Frankfurterische,für eine "Comoedia politica", Hermann Presber

Inc. hebr. 41 - Mishneh Torah : Lib. 1-3

Transliterationsvarianten: Mišne Tōrā. Mischne Tora.