Managing atypical and typical herpetic central nervous system infections: results of a multinational study

There have been many studies pertaining to the management of herpetic meningoencephalitis (HME), but the majority of them have focussed on virologically unconfirmed cases or included only small sample sizes. We have conducted a multicentre study aimed at providing management strategies for HME. Overall, 501 adult patients with PCR-proven HME were included retrospectively from 35 referral centres in 10 countries; 496 patients were found to be eligible for the analysis. Cerebrospinal fluid (CSF) analysis using a PCR assay yielded herpes simplex virus (HSV)-1 DNA in 351 patients (70.8%), HSV-2 DNA in 83 patients (16.7%) and undefined HSV DNA type in 62 patients (12.5%). A total of 379 patients (76.4%) had at least one of the specified characteristics of encephalitis, and we placed these patients into the encephalitis presentation group. The remaining 117 patients (23.6%) had none of these findings, and these patients were placed in the nonencephalitis presentation group. Abnormalities suggestive of encephalitis were detected in magnetic resonance imaging (MRI) in 83.9% of the patients and in electroencephalography (EEG) in 91.0% of patients in the encephalitis presentation group. In the nonencephalitis presentation group, MRI and EEG data were suggestive of encephalitis in 33.3 and 61.9% of patients, respectively. However, the concomitant use of MRI and EEG indicated encephalitis in 96.3 and 87.5% of the cases with and without encephalitic clinical presentation, respectively. Considering the subtle nature of HME, CSF HSV PCR, EEG and MRI data should be collected for all patients with a central nervous system infection.

Guanchias Limitada : a case study of an agrarian reform cooperative and its long-term relationship with a multinational firm in Honduras /

"PN-AAL-046"--Cover.

Mexican manufactured exports and U.S. transnational corporations /

"March 1990."

Handbook of the law of Mexican commercial corporations, including foreign corporations in Mexico (in English) containing explanations of the system of laws of the republic of Mexico and the law of the contract, management and operations of general corporations organized in Mexico; as well as of foreign corporations operating therein; together with complete forms for use by lawyers and corporate officials,

Mode of access: Internet.

Corporations; a study of the origin and development of great business combinations and of their relation to the authority of the state.

Mode of access: Internet.

Histoire des corporations de métiers, depuis leurs origines jusqu'à leur suppression en 1791 : suivie d'une étude sur l'évolution de l'ídee corporative de 1791 à nos jours, et sur le mouvement syndical contemporain /

"Ouvrage couronné par l'Académie française."

Report of the commissioner of corporations on cotton exchanges ...

Mode of access: Internet.

Uniform system of accounts for street railroad corporations. Adopted September 22, 1908.

Cover title.

Communication from Leland Stanford to the Committee on Corporations of the Senate.

Caption title.

Multinational activities of major U.S. automotive producers. Volume I - summary. Final report.

National Highway Traffic Safety Administration, Office of Research and Development, Washington, D.C.

Multinational activities of major U.S. automotive producers. Volume III - research, development, and engineering abroad. Final report.

National Highway Traffic Safety Administration, Office of Research and Development, Washington, D.C.

Multinational activities of major U.S. automotive producers. Volume IV - a preliminary evaluation of technology innovation and transfer. Final report.

National Highway Traffic Safety Administration, Office of Research and Development, Washington, D.C.

Multinational activities of major U.S. automotive producers. Volume V - diffusion of production and sales operations abroad. Final report.

National Highway Traffic Safety Administration, Office of Research and Development, Washington, D.C.

Multinational activities of major U.S. automotive producers. Volume II - data on foreign facilities and operations. Final report.

National Highway Traffic Safety Administration, Office of Research and Development, Washington, D.C.