The effect of climate change on the potential distribution of the European Phlebotomus species and the parasite Leishmania infantum in 2011-2070. A climate envelope modeling approach

Aims: In the Mediterranean areas of Europe, leishmanisasis is one of the most emerging vector-borne diseases. Members of genus Phlebotomus are the primary vectors of the genus Leishmania. To track the human health effect of climate change it is a very important interdisciplinary question to study whether the climatic requirements and geographical distribution of the vectors of human pathogen organisms correlate with each other. Our study intended to explore the potential effects of ongoing climate change, in particular through a potential upward altitudinal and latitudinal shift of the distribution of the parasite Leishmania infantum, its vectors Phlebotomus ariasi, P. neglectus, P. perfiliewi, P. perniciosus, and P. tobbi, and some other sandfly species: P. papatasi, P. sergenti, and P. similis. Methods: By using a climate envelope modelling (CEM) method we modelled the current and future (2011-2070) potential distribution of 8 European sandfly species and L. infantum based on the current distribution using the REMO regional climate model. Results: We found that by the end of the 2060’s most parts of Western Europe can be colonized by sandfly species, mostly by P. ariasi and P. pernicosus. P. ariasi showed the greatest potential northward expansion. For all the studied vectors of L. infantum the entire Mediterranean Basin and South-Eastern Europe seemed to be suitable. L. infantum can affect the Eastern Mediterranean, without notable northward expansion. Our model resulted 1 to 2 months prolongation of the potentially active period of P. neglectus P. papatasi and P. perniciosus for the 2060’s in Southern Hungary. Conclusion: Our findings confirm the concerns that leishmanisais can become a real hazard for the major part of the European population to the end of the 21th century and the Carpathian Basin is a particularly vulnerable area.

The role of death qualification in venirepersons' evaluations of aggravating and mitigating circumstances in capital trials

Death qualification is a part of voir dire that is unique to capital trials. Unlike all other litigation, capital jurors must affirm their willingness to impose both legal standards (either life in prison or the death penalty). Jurors who assert they are able to do so are deemed “death-qualified” and are eligible for capital jury service: jurors who assert that they are unable to do so are deemed “excludable” or “scrupled” and are barred from hearing a death penalty case. During the penalty phase in capital trials, death-qualified jurors weigh the aggravators (i.e., arguments for death) against the mitigators (i.e., arguments for life) in order to determine the sentence. If the aggravating circumstances outweigh the mitigating circumstances, then the jury is to recommend death; if the mitigating circumstances outweigh the aggravating circumstances, then the jury is to recommend life. The jury is free to weigh each aggravating and mitigating circumstance in any matter they see fit. Previous research has found that death qualification impacts jurors' receptiveness to aggravating and mitigating circumstances (e.g., Luginbuhl & Middendorf, 1988). However, these studies utilized the now-defunct Witherspoon rule and did not include a case scenario for participants to reference. The purpose of this study was to investigate whether death qualification affects jurors' endorsements of aggravating and mitigating circumstances when Witt, rather than Witherspoon, is the legal standard for death qualification. Four hundred and fifty venirepersons from the 11 th Judicial Circuit in Miami, Florida completed a booklet of stimulus materials that contained the following: two death qualification questions; a case scenario that included a summary of the guilt and penalty phases of a capital case; a 26-item measure that required participants to endorse aggravators, nonstatutory mitigators, and statutory mitigators on a 6-point Likert scale; and standard demographic questions. Results indicated that death-qualified venirepersons, when compared to excludables, were more likely to endorse aggravating circumstances. Excludable participants, when compared to death-qualified venirepersons, were more likely to endorse nonstatutory mitigators. There was no significant difference between death-qualified and excludable venirepersons with respect to their endorsement of 6 out of 7 statutory mitigators. It would appear that the Furman v. Georgia (1972) decision to declare the death penalty unconstitutional is frustrated by the Lockhart v. McCree (1986) affirmation of death qualification. ^

Efeitos de fungicidas alternativos em folhas de Carthamus tinctorius L. (Asteraceae), potencial espécie para cultivo em agricultura familiar

The currently main development model on global society is driven by an economic rationality that endangers the environment and social justice. More and more, attention to this way of production and consumption is increasing, boosting research for sustainable development, with an environmental rationality that can harmonize nature preservation and welfare of all socioeconomic classes. One of the efforts on this sense is changing the sources supplying the energy demand, replacing fossil fuels for renewable and cleaner sources, such as biofuels. Carthamus tinctorius (safflower) is an oilseed crop with potential for biodiesel production, with good oil yield and chemical profile, allied to good adaptation to climates such like the northeastern semiarid lands of Brazil. With public policies fomentation, the use of this species may be an interesting alternative for family farming. In farming in general, the use of pesticides to prevent and combat diseases and plagues is common, which is not a sustainable practice. Thus, there are researched alternative, less dangerous substances. In this study, it was aimed to assess if neem (Azadirachta indica) leaf extract (20% m/v) and Bordeaux mixture (copper sulfate) have effects on safflower. It was also aimed to verify acceptance of farmers on safflower crop in Apodi, a municipality in Rio Grande do Norte state, Brazil, in view of it being localized in the aimed region for this crop cultivation. Besides that, understanding that the farmers’ knowledge and inclination to adopt the crop is fundamental for the introduction of this species and socioeconomic growth due to its exploration. In addition, a booklet with basic information on safflower was produced. In the field experiment, the fungicides were pulverized on plants cultivated in field experimental plots, with collection of leaf samples for analysis on anatomy, cuticle, and epicuticular wax morphology, the protective layer that interfaces with the surrounding ambient. In Apodi, forty-five farmers from Potiguar Cooperative of Apiculture and Sustainable Rural Development (COOPAPI) underwent semi-structured interviews, which also addressed their assessment on currently cultivated crops and perception of pesticide uses and sustainable alternatives. After comparing using analysis of variance, it was found that there was no difference between treatments in the experiment, as well as no anatomical or morphological modifications. Safflower acceptation among farmers was wide, with 84% of interviewees believing in a perspective of good incomes. The current scenario, comprised of low crop diversity, fragile in face of droughts and plagues, can partially explain this opinion. The booklet was effective in catching people attention for the species potential. There was wide acknowledgement on the importance of alternative pesticides, justified by health security. Based on the assessed parameter in the results of this research, the treatments here utilized may be recommended as fungicides for safflower. Given the crop susceptibility to fungi in heavy rainy period, it is advised that its potential introduction on the region shall be focused on semiarid areas.

A linguagem audiovisual do cinema como elemento integrador da arte e ciência na formação cultural dos professores de ciências e matemática

This work aims to study about the importance of cinema for cultural and professional training of teachers of Natural Sciences and Mathematics. The educational potential of cinema is emphasizing by different authors, which also reveal the teachers' training gap in this issue (media). In this study, we defend the audiovisual language of cinema as an integrating element of Arts and Science for cultural and professional training of teachers. This subject has been developed by different authors, in which the emphasis has been the importance of intelligent dialogue with the world. Specifically, the training of science teachers and mathematics, by the approach of Cinema in its formation, It envisions the possibility of minimizing the dichotomy between humanistic and scientific training, already much discussed by some researchers. Educational products contribute to an effective experience and reflection on the cultural and educational role of the Seventh Art. Considering the Cinema as a possible "bridge" between the two cultures (scientific culture and humanistic culture) and promoting ownership of audiovisual language in teacher training It was accomplished the I Exhibition - Cultural Spring: Cinema and Science Education in UFRN. The production of the booklet "Topics of History, Language and Art of Cinema for Science and Mathematics Teachers," and its application in a short course in the XXI National Symposium on Physics Teaching also aimed to contribute to the approximation of Science and Art in training teachers.

Concepções dos professores da educação básica sobre as feiras de ciência

Currently the Science fairs in Brazil have gained great incentive, examples are the regulations that the government has been implementing in education and the financing of public calls for events throughout the national territory. However, even with this incentive, some researchers point out that the scientific fairs and shows are still interpreted as an extemporaneous work by teachers. In order to know the views of basic education teachers about the fairs of Science, proposed to carry out this research. Given this situation, based mediation theory and sociocultural interaction Vygotsky (2001), the theory of instrumentalism Dewey (2002) and the proposed education through research Galiazzi e Moraes (2002), we sought to understand the importance of fair and their benefits as well as the presence in the talks of respondents. In order to analyze the answers of respondents, used to discourse analysis proposed by Eni Orlandi (2009), in which it is observed and is an interpretation of the speech of teachers, considering their interpretation and how to shape their thinking on the research object. In analyzing the results of the survey, it was noted that the teachers interviewed know the importance and objectives of science fairs, however experience difficulties that often does not allow these events to be carried out. In seeking to assist them to minimize these difficulties, it was realized the need for a product to make available guidance on how to develop research projects and assemblies of science fairs, that would provide an education for the research. Thus, resulting from research, was set up a blog and a booklet with texts, articles and report templates.

Graded Exercise Therapy Guided Self-Help Trial for Patients with Chronic Fatigue Syndrome (GETSET): Protocol for a Randomized Controlled Trial and Interview Study

Background: Chronic fatigue syndrome, also known as myalgic encephalomyelitis (CFS/ME), is characterized by chronic disabling fatigue and other symptoms, which are not explained by an alternative diagnosis. Previous trials have suggested that graded exercise therapy (GET) is an effective and safe treatment. GET itself is therapist-intensive with limited availability. Objective: While guided self-help based on cognitive behavior therapy appears helpful to patients, Guided graded Exercise Self-help (GES) is yet to be tested. Methods: This pragmatic randomized controlled trial is set within 2 specialist CFS/ME services in the South of England. Adults attending secondary care clinics with National Institute for Health and Clinical Excellence (NICE)-defined CFS/ME (N=218) will be randomly allocated to specialist medical care (SMC) or SMC plus GES while on a waiting list for therapist-delivered rehabilitation. GES will consist of a structured booklet describing a 6-step graded exercise program, supported by up to 4 face-to-face/telephone/Skype™ consultations with a GES-trained physiotherapist (no more than 90 minutes in total) over 8 weeks. The primary outcomes at 12-weeks after randomization will be physical function (SF-36 physical functioning subscale) and fatigue (Chalder Fatigue Questionnaire). Secondary outcomes will include healthcare costs, adverse outcomes, and self-rated global impression change scores. We will follow up all participants until 1 year after randomization. We will also undertake qualitative interviews of a sample of participants who received GES, looking at perceptions and experiences of those who improved and worsened. Results: The project was funded in 2011 and enrolment was completed in December 2014, with follow-up completed in March 2016. Data analysis is currently underway and the first results are expected to be submitted soon. Conclusions: This study will indicate whether adding GES to SMC will benefit patients who often spend many months waiting for rehabilitative therapy with little or no improvement being made during that time. The study will indicate whether this type of guided self-management is cost-effective and safe. If this trial shows GES to be acceptable, safe, and comparatively effective, the GES booklet could be made available on the Internet as a practitioner and therapist resource for clinics to recommend, with the caveat that patients also be supported with guidance from a trained physiotherapist. The pragmatic approach in this trial means that GES findings will be generalizable to usual National Health Service (NHS) practice.

Las menudencias impresas en los archivos y bibliotecas: clasificación, terminología y guía para su identificación

Cuando abordamos un trabajo de investigación en cualquier centro de documentación que albergue fondo antiguo a menudo nos topamos con papeles o cuadernillos de pocas hojas que muchas veces han pasado desapercibidos y están sin catalogar. La naturaleza de éstos resulta diversa y, en ocasiones, también su identificación puede llegar a ser compleja seguramente por el mero hecho de aparecer muchos de ellos descontextualizados. Por esta razón, el presente artículo pretende establecer una guía sistemática que englobe, clasifique y describa aquellos más habituales en los archivos para facilitar así su identificación.

Get the Word Out: Public relations tips for transportation agencies

This booklet, financed through the Local Technical Assistance Program (LTAP) in Iowa, provides public relations tips for transportation agencies. Information is provided on how to deal with the media, especially how to develop story ideas, where to send them, and how to write more effective news releases. Also included is information on handling complaints, speaking to the public, and working with elected officials.

The world beneath your feet : a closer look at soil and roots / by Mark Mϋller.

A booklet about soil, soil ecology and soil conservation produced by the Iowa Living Roadway Trust Fund and the Iowa Department of Transportation.

Effectiveness and Cost-effectiveness of Outpatient Physiotherapy After Knee Replacement for Osteoarthritis: Study Protocol for a Randomised Controlled Trial

Background: Primary total knee replacement is a common operation that is performed to provide pain relief and restore functional ability. Inpatient physiotherapy is routinely provided after surgery to enhance recovery prior to hospital discharge. However, international variation exists in the provision of outpatient physiotherapy after hospital discharge. While evidence indicates that outpatient physiotherapy can improve short-term function, the longer term benefits are unknown. The aim of this randomised controlled trial is to evaluate the long-term clinical effectiveness and cost-effectiveness of a 6-week group-based outpatient physiotherapy intervention following knee replacement. Methods/design: Two hundred and fifty-six patients waiting for knee replacement because of osteoarthritis will be recruited from two orthopaedic centres. Participants randomised to the usual-care group (n = 128) will be given a booklet about exercise and referred for physiotherapy if deemed appropriate by the clinical care team. The intervention group (n = 128) will receive the same usual care and additionally be invited to attend a group-based outpatient physiotherapy class starting 6 weeks after surgery. The 1-hour class will be run on a weekly basis over 6 weeks and will involve task-orientated and individualised exercises. The primary outcome will be the Lower Extremity Functional Scale at 12 months post-operative. Secondary outcomes include: quality of life, knee pain and function, depression, anxiety and satisfaction. Data collection will be by questionnaire prior to surgery and 3, 6 and 12 months after surgery and will include a resource-use questionnaire to enable a trial-based economic evaluation. Trial participation and satisfaction with the classes will be evaluated through structured telephone interviews. The primary statistical and economic analyses will be conducted on an intention-to-treat basis with and without imputation of missing data. The primary economic result will estimate the incremental cost per quality-adjusted life year gained from this intervention from a National Health Services (NHS) and personal social services perspective. Discussion: This research aims to benefit patients and the NHS by providing evidence on the long-term effectiveness and cost-effectiveness of outpatient physiotherapy after knee replacement. If the intervention is found to be effective and cost-effective, implementation into clinical practice could lead to improvement in patients’ outcomes and improved health care resource efficiency.

Deep Red: The Quintessential Giallo

Essay exploring the giallo genre using Dario Argento's Profondo Rosso/Deep Red as example. Produced for Arrow Video's Blu-ray of Deep Red, and included as part of the full colour booklet.

9 Lives of the Black Cat

This is a short essay included in the accompanying booklet for Arrow Video's Blu-ray collection titled "Edgar Allan Poe's Black Cats": The Black Cat (Lucio Fulci, 1981) & Your Vice is a Locked Room and Only I have the Key (Sergio Martino, 1972)

Iowa Hunting and Trapping Regulations, 2016-2017

This booklet is not a complete set of hunting laws. It contains basic information needed during the hunting and trapping seasons.