979 resultados para Tadashi Suzuki


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Introduction: Physical exercise are related to high oxygen consumption, leading to increase on reactive oxygen species (ROS) generation and subsequent oxidative stress. Concomitantly, physical training can improve the antioxidant defense systems, reducing the deleterious activity of ROS. The yerba mate (Ilex paraguariensis) has several bioactive compounds in its composition, providing important antioxidant activity in improving defense systems and reducing the damage caused by ROS. Few studies related to yerba mate with antioxidant effects during exercise. Objective: Evaluate whether the consumption-based drink yerba mate (Ilex paraguariensis) is able to increase the total antioxidant performance (TAP) after an exhaustive test on a treadmill. Methods: The sample counted with 15 female soccers players from Botucatu-SP female soccer team with a mean age of 22.1 ± 4.2 years. For laboratory tests , it was evaluated: triglycerides (TG), total cholesterol (TC) and fractions, glucose and gamma-GT were dosed by dry chemistry (Vitros® System, Johnson & Johnson). LDL-cholesterol was obtained by Friedwald formula. Total antioxidant performance (TAP) was obtained by the method of fluorescence assay for the measurement of plasma. Weight, height and body mass index (IMC) were measured, percentage of body fat was obtained by bioeletrical impedance analysis (Biodinâmics, modelo 450, USA). Arterial blood pressure was checked by auscultatory method and cardiorespiratory fitness was determined by ergoespirometric test (Ramp Protocol). Maltodextrin was supplemented (30 g in 400 ml) 30 minutes after M0 with placebo (400 ml) or mate (5 g in 400 ml of water). Statistical analysis: ANOVA for repeated measures followed by Tukey's test set, p<0.05. Results: There was a decrease in the pH after exhaustive testing for water and tea (p<0.0001), the same was observed for bicarbonate (p<0.0001). In both groups pO₂ increased for ...

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The cancer anorexia-cachexia syndrome is the most common paraneoplastic syndrome in Veterinary Medicine. It is characterized by severe loss of muscle mass and adipose tissue resulting in severe unintentional weight loss, anemia, fatigue, negative nitrogen balance, immune dysfuntion and other metabolic disturbances. The SAC is not only a result of inadequate intake of nutrients. The tumor requires large amounts of nutrients to allow growth and causes changes in pacient metabolism to get this energy. Recent studies suggest that the metabolic changes by cancer can be measured by hormones and cytokines produced or by the patient or the tumor, but this not completely understood. Animals with SAC have lower survival time, the greater chance of complications during treatment and lower quality of life. With the increase in the number of cancer cases in domestic animals and longer lifespan after diagnosis of malignant disease through the use of antineoplastics drugs, diagnosis and treatment of cancer anorexia-cachexia syndrome has shown great importance in that patients may have higher survival then better quality of life. This paper aims to provide information about this complex and multifunctional syndrome and its possible treatments

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The city of São Paulo has, since the beginning of the expansion of its urban sprawl, represented relations of conflicts and contradictions between society and nature. Once the way society relates to nature is defined by how the social agents themselves correlate in certain social and historical contexts, the ways of interaction between the social and natural elements will be different according to the forms of production and appropriation of the urban space. Even more evident is the case of the great national metropolis, given its demographic dimensions and historical conditions, the process of urban expansion follows a logic where spaces of better quality for housing are occupied by those of better financial conditions. Thus, although there are exceptions, the poorest people live in places less desirable, in less resilient environments of lower environmental quality, relating to nature and its phenomena with greater risks. These risks are reflected here as recurring flooding, mudslides and landslides for which the rain is constantly blamed. So we have a situation where it is clear that a weather phenomenon differently interacts with different social groups. In this context, the study was conducted to compare extreme events occurred in two regions of São Paulo: the Freguesia do O, in the north side, and M'Boi Mirim, in the south side. Both are regions with large number of risk areas and are in the same urban climate unit. However, they present different conditions of social vulnerability. With the investigation of each extreme rain event occurred in the two regions, in the period of 2000-2010, supplemented by field research, we tried to observe how far the rain, with his intensity and volume, can, in fact, be related to the accidents.

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The current problematic of the construction and demolition (C&D) waste faced for the Brazilian cities, is one of the main degradation factors of the environment, over all about the promise of the urban ambient quality. This scenery must mainly to the unsustainable management adopted by the great majority of the Brazilian cities. Therefore, this work aims at to offer subsidies for medium cities, having as study object the city of Rio Claro-SP, (Brazil), in the elaboration of plans and integrated programs of sustainable management of the construction and demolition waste, in accordance with CONAMA Resolution nº 307/2002, that’s set up a sustainable management system of C&D waste. In this direction, the diagnosis of the management was elaborated for the city of Rio Claro, (generation, collects, transport and disposal) and the public administration of the construction and demolition waste, as well as of the study of the related aspects with C&D waste recycling plant. Later, was suggested a plan of improvements for the public manager of C&D waste: areas of temporary disposal to facility the appropriating destination, appropriated areas of final disposal, incentives to the recycling of C&D waste, new legislations, education and orientation programs and adequacy the agents of C&D waste management (generating, transporting, addressee and public manager), directing for an environmental, economic and social sustainability.

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The following paper means to develop a program to make structural analysis of space trusses. The program to be implemented was based on the concepts of the finite element method and used the programing resources of Visual Basic for Applications (VBA) for the Excel Software®. Being Excel® a software of easy access, low cost, capacity to make matrix calculations and with advanced resources of VBA programing, it is possible to develop an economic solution, efficient and precise for structural analysis of space trusses. Firstly is presented a finite elemento method and the space truss. Then is developed a few important algorithms to be used during the development of the program and also the use of a few resources of VBA. And to validate the quality, efficiency and precision of the results, these are compared with the established commercial software Ansys

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The demographic census is the largest and most important socioeconomic research of the country since it portrays the situation closer to the reality of the population. Their result allows public policy making aimed at improving the quality of life, socioeconomic development and provides information for decision making on public and private sector. Due to the large amount of data collected, the processing of such information requires increasingly use information technology to facilitate processing. Therefore, the increasingly common use of the Geographic Information System (GIS) in various fields of knowledge contributes to the job achievement given its ability to collect, store, retrieve and view data. Following this trend, the Brazilian Institute of Geography and Statics (IBGE) also used this tool in the development of cartographic inputs, wich plays a key role for the data collection range nationwide

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Dark Water is the title of the translation of a short story, ―Floating Water‖, from the book Honogurai mizu no soko kara by Koji Suzuki, originally published in Japan, that the Japanese director Hideo Nakata adapted for the cinema and that was remade by the Brazilian director Walter Salles Jr. The objective of this study is to analyse Walter Salles’ film to demonstrate how it resolved the problems of transcreation, whilst at the same time it fulfilled commercial and artistic functions and incorporated the traces of its aesthetic trajectory. In this case, attention is drawn to the types of relationship between literature and cinema, to the metalinguistic function as a generator of poetics and of an interesting dialogue between genres.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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We demonstrate the supercontinuum (SC) generation in a suspended-core As2S3 chalcogenide microstructured optical fiber (MOF). The variation of SC is investigated by changing the fiber length, pump peak power and pump wavelength. In the case of long fibers (20 and 40 cm), the SC ranges are discontinuous and stop at the wavelengths shorter than 3500 nm, due to the absorption of fiber. In the case of short fibers (1.3 and 2.4 cm), the SC ranges are continuous and can extend to the wavelengths longer than 4 μm. The SC broadening is observed when the pump peak power increases from 0.24 to 1.32 kW at 2500 nm. The SC range increases with the pump wavelength changing from 2200 to 2600 nm, corresponding to the dispersion of As2S3 MOF from the normal to anomalous region. The SC generation is simulated by the generalized nonlinear Schrödinger equation. The simulation includes the SC difference between 1.3 and 2.4 cm long fiber by 2500 nm pumping, the variation of SC with pump peak power in 2.4 cm long fiber, and the variation of SC with pump wavelength in 1.3 cm long fiber. The simulation agrees well with the experiment.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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To quantify fibrin degradation products after topical and subconjunctival administration of recombinant tissue plasminogen activator in rabbits. Methods: Fibrin formation was induced in the anterior chamber in 25 rabbits. Subsequently, five rabbits received an injection of r-TPA (positive control) in the anterior chamber, another 10 received a subconjunctival injection of r-TPA, and the remaining 10 received instillations of topical r-TPA. Afterwards, samples of aqueous humor were collected and semi-quantitative analysis of fibrin degradation products (FDP) was performed. Results: No statistical differences were noted between the treatment and control groups at any time point. Fibrin degradation products semi-quantification showed statistical improvement in the control group and the subconjunctival group. Conclusion: Fibrin degradation products were observed in the anterior chamber after subconjunctival administration of r-TPA. However, it was probably not sufficient to cause fibrin degradation. Topical r-TPA did not effectively absorb anterior chamber fibrin.

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Objective. This study aimed to investigate the surface roughness of composite resins subjected to thermal cycles procedure. Materials and methods. Two microfill, four microhybrid and four nanofill composites were used. The surface roughness (Ra) was initially measured in a profilometer using a cut-off 0f 0.25 mm, after 3000 and 10,000 thermal cycles. Data were subjected to ANOVA and Fischer's test (alpha = 0.05). Results. Overall, 3000 thermal cycles increased the surface roughness values for all materials and there was a trend in all groups to decrease the roughness after 10,000 thermal cycles. Conclusions. The composition of material, including the type of organic matrix, could be more relevant to roughness maintenance over time than the general behavior of composites based on particles fillers. The maintenance of smooth surface in resin-based composite restorations is totally dependent of organic composition of the material.