Genome expansion and gene loss in powdery mildew fungi reveal tradeoffs in extreme parasitism

Powdery mildews are phytopathogens whose growth and reproduction are entirely dependent on living plant cells. The molecular basis of this life-style, obligate biotrophy, remains unknown. We present the genome analysis of barley powdery mildew, Blumeria graminis f.sp. hordei (Blumeria), as well as a comparison with the analysis of two powdery mildews pathogenic on dicotyledonous plants. These genomes display massive retrotransposon proliferation, genome-size expansion, and gene losses. The missing genes encode enzymes of primary and secondary metabolism, carbohydrate-active enzymes, and transporters, probably reflecting their redundancy in an exclusively biotrophic life-style. Among the 248 candidate effectors of pathogenesis identified in the Blumeria genome, very few (less than 10) define a core set conserved in all three mildews, suggesting thatmost effectors represent species-specific adaptations.

Pianos for the people: the manufacture, marketing and sale of pianos as consumer durables, 1850-1914

During the second half of the nineteenth century, British society experienced a rise in real incomes and a change in its composition, with the expansion of the middle classes. These two factors led to a consumer revolution, with a growing, but still segmented, demand for household goods that could express status and aspiration. At the same time technological changes and new ways of marketing and selling goods made these goods more affordable. This paper analyzes these themes and the process of mediation that took place between producers, retailers, and consumers, by looking at the most culturally symbolic of nineteenth century consumer goods, the piano.

‘The European Dream of Franz Josef Strauss’

Franz Josef Strauss, West German Minister of Atomic Energy and Minister of Defence, pursued a project by which European political integration was to be paralleled by co-operation in the field of nuclear energy and indeed nuclear weapons. It has often been alleged that this covered nationalist German ambitions to turn Germany into a nuclear power in its own rights. Seen in the context of his European integration programme - which foundered on the devotion of French President de Gaulle to French national sovereignty - Strauss' overall policy suggests that he did indeed aim not to obtain nuclear weapons for Germany, but for an integrated European superstate.

Missionary children: The French Holy Childhood Association in European context, 1843-c.1914

In the mid-nineteenth century, thousands of children in Europe and beyond were organized into battalions of fundraisers for overseas missions. By the end of the century these juvenile missionary organizations had become a global movement, generating millions of pounds in revenue each year. While the transnational nature of the children’s missions and publications has been well-documented by historians, the focus has tended to be on the connections that were established by encounters between the young western donors, missionaries overseas and the non-western ‘other’ constructed by their work. A full exploration of the European political, social and cultural concerns that produced the juvenile missionaries movement and the trans-European networks that sustained it are currently missing from historical accounts of the phenomenon. This article looks at the largest of these organizations, the Catholic mission for children, the French Holy Childhood Association (L’Œuvre de la sainte enfance), to understand how the principles this mission sought to impose abroad were above all an expression of anxieties at home about the role of religion in the family, childhood and in civil society as western polities were modernizing and secularizing in the nineteenth century.

Climate and carbon cycle changes from 1850 to 2100 in MPI-ESM simulations for the Coupled Model Intercomparison Project phase 5

The new Max-Planck-Institute Earth System Model (MPI-ESM) is used in the Coupled Model Intercomparison Project phase 5 (CMIP5) in a series of climate change experiments for either idealized CO2-only forcing or forcings based on observations and the Representative Concentration Pathway (RCP) scenarios. The paper gives an overview of the model configurations, experiments related forcings, and initialization procedures and presents results for the simulated changes in climate and carbon cycle. It is found that the climate feedback depends on the global warming and possibly the forcing history. The global warming from climatological 1850 conditions to 2080–2100 ranges from 1.5°C under the RCP2.6 scenario to 4.4°C under the RCP8.5 scenario. Over this range, the patterns of temperature and precipitation change are nearly independent of the global warming. The model shows a tendency to reduce the ocean heat uptake efficiency toward a warmer climate, and hence acceleration in warming in the later years. The precipitation sensitivity can be as high as 2.5% K−1 if the CO2 concentration is constant, or as small as 1.6% K−1, if the CO2 concentration is increasing. The oceanic uptake of anthropogenic carbon increases over time in all scenarios, being smallest in the experiment forced by RCP2.6 and largest in that for RCP8.5. The land also serves as a net carbon sink in all scenarios, predominantly in boreal regions. The strong tropical carbon sources found in the RCP2.6 and RCP8.5 experiments are almost absent in the RCP4.5 experiment, which can be explained by reforestation in the RCP4.5 scenario.

Franz Neumann, the rule of law and the unfulfilled promise of classical liberal thought

This thesis draws on the work of Franz Neumann, a critical theorist associated with the early Frankfurt School, to evaluate liberal arguments about political legitimacy and to develop an original account of the justification for the liberal state.

The only way is up: retail format saturation and the demise of the American five and dime store, 1914-1941

We examine a classic ‘wheel of retailing’ episode – the abandonment of the five and dime pricing formula by American variety chains. These switched from a conventional product lifecycle, focusing on cost reduction through standardisation, to a reverse path up the ‘service cost - unit value’ continuum. We show that, rather than reflecting deteriorating managerial acumen, this was a response to the continued imperative for growth following retail format saturation. Firm-specific (rather than format-specific) competitive advantages were too weak for any chain to be confident it could win a within-format price war, making inter-format competition through raising price points more attractive.

Spädbarnsdöd i Västsverige : en studie av spädbarnsdödligheten i Bollebygd, Morlanda och Karl Johans församling under två perioder på 1800-talet

Uppsatsen syfte var att studera spädbarnsdödlighet i tre olikartade västsvenska miljöer under två perioder på 1800-talet. Områdena är Bollebygd, Morlanda och Karl Johans församling i Göteborg och representerar alla olika miljöer (Bollebygd – landsbygd, Morlanda – kust och Karl Johan - stadsmiljö) där spädbarnsdödligheten enligt tidigare forskning har varit av olika omfattning och karaktär. Den primära frågeställningen är hur de yttre omständigheterna påverkar de allra minsta barnen. Ett sekundärt syfte var att försöka utröna vilka uppfödningsvanor som var dominerande. De primärkällor som används är dels födelse- och dopböcker samt provinsialläkarrapporter. Studiens tydliga mönster är att spädbarnsdödligheten var högre i staden (Karl Johan) men att den ändå inte var så hög som väntat i jämförelse med övriga städer i riket. I jämförelse med riks¬genomsnittet uppvisar både Morlanda och Bollebygd en låg spädbarnsdödlighet. Genom att se hur spädbarnsdödligheten fördelar sig över årstiderna och över det första levnadsåret samt vilka dödsorsaker som finns angivna kan med viss försiktighet antas att spädbarnen ofta ammades i alla fall upp till tre månaders ålder. Ett annat resultat av studien är att flickorna i alla undersöknings¬områden och perioder utom ett uppvisar en överdödlighet i jämförelse med pojkarna, vilket är anmärkningsvärt då pojkarna i de allra flesta fall brukar ha en överdödlighet.