Hardwicke's science-gossip : an illustrated medium of interchange and gossip for students and lovers of nature.

v.9=no.97-108 (1873)

Hardwicke's science-gossip : an illustrated medium of interchange and gossip for students and lovers of nature.

v.25=no.289-300 (1889)

Hardwicke's science-gossip : an illustrated medium of interchange and gossip for students and lovers of nature.

v.8=no.85-96 (1872)

Hardwicke's science-gossip : an illustrated medium of interchange and gossip for students and lovers of nature.

v.3=no.25-36 (1867)

Hardwicke's science-gossip : an illustrated medium of interchange and gossip for students and lovers of nature.

v.13=no.145-156 (1877)

Hardwicke's science-gossip : an illustrated medium of interchange and gossip for students and lovers of nature.

v.27=no.313-324 (1891)

Hardwicke's science-gossip : an illustrated medium of interchange and gossip for students and lovers of nature.

v.15=no.169-180 (1879)

Hardwicke's science-gossip : an illustrated medium of interchange and gossip for students and lovers of nature.

v.5=no.49-60 (1869)

Clinical Coronary In-Stent Restenosis Follow-Up after Treatment and Analyses of Clinical Outcomes

Background: Clinical in-stent restenosis (CISR) is the main limitation of coronary angioplasty with stent implantation. Objective: Describe the clinical and angiographic characteristics of CISR and the outcomes over a minimum follow-up of 12 months after its diagnosis and treatment. Methods: We analyzed in 110 consecutive patients with CISR the clinical presentation, angiographic characteristics, treatment and combined primary outcomes (cardiovascular death, nonfatal acute myocardial infarction [AMI]) and combined secondary (unstable angina with hospitalization, target vessel revascularization and target lesion revascularization) during a minimal follow-up of one year. Results: Mean age was 61 ± 11 years (68.2% males). Clinical presentations included acute coronary syndrome (ACS) in 62.7% and proliferative ISR in 34.5%. CISR was treated with implantation of drug-eluting stents (DES) in 36.4%, Bare Metal Stent (BMS) in 23.6%, myocardial revascularization surgery in 18.2%, balloon angioplasty in 15.5% and clinical treatment in 6.4%. During a median follow-up of 19.7 months, the primary outcome occurred in 18 patients, including 6 (5.5%) deaths and 13 (11.8%) AMI events. Twenty-four patients presented a secondary outcome. Predictors of the primary outcome were CISR with DES (HR = 4.36 [1.44–12.85]; p = 0.009) and clinical treatment for CISR (HR = 10.66 [2.53–44.87]; p = 0.001). Treatment of CISR with BMS (HR = 4.08 [1.75–9.48]; p = 0.001) and clinical therapy (HR = 6.29 [1.35–29.38]; p = 0.019) emerged as predictors of a secondary outcome. Conclusion: Patients with CISR present in most cases with ACS and with a high frequency of adverse events during a medium-term follow-up.

Hardwicke's science-gossip : an illustrated medium of interchange and gossip for students and lovers of nature.

v.4=no.37-48 (1868)

Hardwicke's science-gossip : an illustrated medium of interchange and gossip for students and lovers of nature.

v.6=no.61-72 (1870)

Hardwicke's science-gossip : an illustrated medium of interchange and gossip for students and lovers of nature.

v.21=no.241-252 (1885)

Hardwicke's science-gossip : an illustrated medium of interchange and gossip for students and lovers of nature.

v.16=no.181-192 (1880)

Hardwicke's science-gossip : an illustrated medium of interchange and gossip for students and lovers of nature.

v.12=no.133-144;Index v.1-12 (1865-1876)

Hardwicke's science-gossip : an illustrated medium of interchange and gossip for students and lovers of nature.

v.19=no.217-228 (1883)