Catalogue des peintures, aquarelles, dessins et lithographies de A. Raffet, des tableaux anciens et modernes... et des objets d'art formant la succession de feu M. Aug. Raffet fils... vente le 16 mars 1911, hôtel Drouot... / [experts] Mannheim, Delteil, Féral ; [notice de] François Courboin

[Vente. Estampes. 1911-03-16. Paris]

State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology.

Integrated approaches using different in vitro methods in combination with bioinformatics can (i) increase the success rate and speed of drug development; (ii) improve the accuracy of toxicological risk assessment; and (iii) increase our understanding of disease. Three-dimensional (3D) cell culture models are important building blocks of this strategy which has emerged during the last years. The majority of these models are organotypic, i.e., they aim to reproduce major functions of an organ or organ system. This implies in many cases that more than one cell type forms the 3D structure, and often matrix elements play an important role. This review summarizes the state of the art concerning commonalities of the different models. For instance, the theory of mass transport/metabolite exchange in 3D systems and the special analytical requirements for test endpoints in organotypic cultures are discussed in detail. In the next part, 3D model systems for selected organs--liver, lung, skin, brain--are presented and characterized in dedicated chapters. Also, 3D approaches to the modeling of tumors are presented and discussed. All chapters give a historical background, illustrate the large variety of approaches, and highlight up- and downsides as well as specific requirements. Moreover, they refer to the application in disease modeling, drug discovery and safety assessment. Finally, consensus recommendations indicate a roadmap for the successful implementation of 3D models in routine screening. It is expected that the use of such models will accelerate progress by reducing error rates and wrong predictions from compound testing.

State of Iowa Transportation Map, 2011

This document is the State Map of Iowa, both front and back of the year in the title. All maps were are in pdf format and can be used as a historical reference.

Vehicle Traffic Map, 2010

Vehicle Traffic Map produced by the Iowa Department of Transportation.

Truck Traffic Map, 2010

Vehicle Traffic Map produced by the Iowa Department of Transportation.

Iowa State Railroad Map, July 1, 2010

Iowa railroad map of Iowa trains.

2009 Iowa Transportation Map for Bicyclists, 2009

This online Adobe Portable Document Format (PDF) version of the 2009 Iowa Transportation Map for Bicyclists was developed using the same electronic files that were used to create the widely distributed paper version of the map. The files have been translated to allow access for the viewing customers while still maintaining the detail necessary to display the map content. The PDF conversion utility from Adobe compressed the 75MB main map image file down to a 4.2MB file. This 4.2MB file may still take time to download so please be patient. We believe the end result is well worth the wait. The city detail maps are much smaller and will download more quickly.

Interstate Highway Map Indicating Vertical Clearance, May 15, 2011

The State of Iowa [STATE] and the Iowa Department of Transportation [IDOT] hereby is claim any warranty of any kind, express or implied, in reference to the information contained herein. The STATE and the IDOT neither assume nor authorize any person to assume for the STATE or the IDOT any liability in connection with the information contained herein, and there are no oral agreements or warranties regarding the information contained herein. Each and every person is hereby notified that the vertical clearances specified herein are subject to change due to resurfacing, surface buckling, weather conditions, or any other event. It is the responsibility of each and every vehicle operator to ascertain whether sufficient ACTUAL vertical clearance exists to move his vehicle or motor vehicle between the roadway and the underpasses and bridges listed herein. The May 15 date on this map reflects the end of the update schedule for the previous calendar year. Any vertical clearance restrictions which could or may change AFTER this date will not be reflected on this map. For the latest information on vertical clearance restrictions call the Office of Motor Carrier Services in Ankeny, (515) 237-3264 or visit http://www.iowadot.gov/mvd/omcs.

[Illustrations de L'Art de raffiner le sucre] / Ludovic Simonneau, grav. ; Henri-Louis Duhamel du Monceau, aut. du texte

Comprend : [pl.I en reg. p.78 : moulin à sucre de canne employé en Amérique.] [Cote : V 3992/Microfilm R 122 218] ; [pl.II en reg. p.78 : cellier où l'on stocke les barils de sucre brut. Raffinage du sucre.] [Cote : V 3992/Microfilm R 122 218] ; [pl.III en reg. p.78 : la halle aux chaudières. Raffinage du sucre. Planche gravée d'après un dessin de M. Desfriches.] [Cote : V 3992/Microfilm R 122 218] ; [pl.IV en reg. p.78 : la halle aux chaudières. Raffinage du sucre.] [Cote : V 3992/Microfilm R 122 218] ; [pl.V en reg. p.78 : comment sont montée les chaudières pour le raffinage du sucre.] [Cote : V 3992/Microfilm R 122 218] ; [pl.VI en reg. p.78 : diverses formes pour monter les pains de sucre. Raffinage du sucre.] [Cote : V 3992/Microfilm R 122 218] ; [pl.VII en reg. p.78 : comment travailler au traitement et au raffinage du sucre.] [Cote : V 3992/Microfilm R 122 218] ; [pl.VIII en reg. p.78 : un grenier dit aux pièces. Raffinage et stockage du sucre.] [Cote : V 3992/Microfilm R 122 218] ; [pl.IX en reg. p.78 : préparation des pins de sucre avant de le mettre à l'étuve. Manière de les mettre en papier et en corde. La mise en tonne. Le travail des écumes.] [Cote : V 3992/Microfilm R 122 218] ; [pl.X en reg. p.78 : détail d'une étuve à sucre.] [Cote : V 3992/Microfilm R 122 218]